ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 15/309 79/7206 9.71062098693e-07 ko04380 Osteoclast differentiation 18/309 134/7206 1.4554950283e-05 ko05150 Staphylococcus aureus infection 9/309 36/7206 1.47441970441e-05 ko04022 cGMP-PKG signaling pathway 24/309 216/7206 1.56686771679e-05 ko04060 Cytokine-cytokine receptor interaction 22/309 191/7206 2.03046225786e-05 ko05144 Malaria 9/309 45/7206 9.87065976588e-05 ko05034 Alcoholism 1/309 238/7206 0.000503426155188 ko04611 Platelet activation 17/309 163/7206 0.000584765865996 ko04261 Adrenergic signaling in cardiomyocytes 19/309 205/7206 0.00132550248495 ko04512 ECM-receptor interaction 10/309 79/7206 0.00188862805542 ko05416 Viral myocarditis 8/309 55/7206 0.00218716332809 ko04020 Calcium signaling pathway 22/309 265/7206 0.00281148802269 ko04260 Cardiac muscle contraction 11/309 98/7206 0.00301861041989 ko01200 Carbon metabolism 13/309 128/7206 0.0032115034705 ko04922 Glucagon signaling pathway 13/309 128/7206 0.0032115034705 ko04672 Intestinal immune network for IgA production 6/309 37/7206 0.00447177622272 ko04921 Oxytocin signaling pathway 18/309 209/7206 0.00461606250099 ko00710 Carbon fixation in photosynthetic organisms 5/309 27/7206 0.00520275763318 ko04659 Th17 cell differentiation 11/309 106/7206 0.00553214986103 ko04270 Vascular smooth muscle contraction 14/309 154/7206 0.00726649966957 ko04974 Protein digestion and absorption 10/309 96/7206 0.00779982662557 ko04658 Th1 and Th2 cell differentiation 10/309 96/7206 0.00779982662557 ko04064 NF-kappa B signaling pathway 10/309 96/7206 0.00779982662557 ko05340 Primary immunodeficiency 5/309 30/7206 0.00826954445686 ko04510 Focal adhesion 19/309 240/7206 0.00875048632717 ko05321 Inflammatory bowel disease (IBD) 7/309 56/7206 0.00949955216691 ko05410 Hypertrophic cardiomyopathy (HCM) 10/309 100/7206 0.0103041959079 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/309 4/7206 0.0103834878705 ko00620 Pyruvate metabolism 6/309 46/7206 0.0130622147404 ko00010 Glycolysis / Gluconeogenesis 8/309 74/7206 0.013434130679 ko05134 Legionellosis 8/309 74/7206 0.013434130679 ko05323 Rheumatoid arthritis 9/309 89/7206 0.013631028404 ko00330 Arginine and proline metabolism 7/309 61/7206 0.0149095249355 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/309 135/7206 0.0153925522486 ko00020 Citrate cycle (TCA cycle) 5/309 35/7206 0.0158300921737 ko00500 Starch and sucrose metabolism 5/309 35/7206 0.0158300921737 ko04640 Hematopoietic cell lineage 7/309 64/7206 0.0190503280308 ko03040 Spliceosome 1/309 145/7206 0.0215853372572 ko04110 Cell cycle 1/309 145/7206 0.0215853372572 ko05145 Toxoplasmosis 11/309 126/7206 0.0228396185411 ko00362 Benzoate degradation 2/309 6/7206 0.0245174832698 ko05414 Dilated cardiomyopathy 10/309 112/7206 0.0286277456571 ko01230 Biosynthesis of amino acids 8/309 85/7206 0.0287023570203 ko04723 Retrograde endocannabinoid signaling 2/309 175/7206 0.0352974216797 ko05166 HTLV-I infection 20/309 292/7206 0.037254581305 ko00071 Fatty acid degradation 5/309 45/7206 0.0422070579462 ko04660 T cell receptor signaling pathway 10/309 124/7206 0.0439347202928 ko03010 Ribosome 1/309 129/7206 0.045193482858 ko04622 RIG-I-like receptor signaling pathway 6/309 62/7206 0.0487362425227