ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	27/532	56/7206	1.42837899212e-16
ko04360	Axon guidance	55/532	233/7206	2.40867205962e-15
ko04728	Dopaminergic synapse	45/532	185/7206	3.09617283628e-13
ko04080	Neuroactive ligand-receptor interaction	73/532	423/7206	2.10224377441e-12
ko04724	Glutamatergic synapse	37/532	152/7206	4.25286388424e-11
ko04727	GABAergic synapse	30/532	110/7206	1.55989673142e-10
ko04721	Synaptic vesicle cycle	25/532	80/7206	2.26607491702e-10
ko05032	Morphine addiction	29/532	110/7206	7.66180170244e-10
ko04024	cAMP signaling pathway	49/532	279/7206	6.77961579214e-09
ko04725	Cholinergic synapse	33/532	160/7206	4.24778048598e-08
ko04723	Retrograde endocannabinoid signaling	34/532	175/7206	1.23633141428e-07
ko04514	Cell adhesion molecules (CAMs)	26/532	130/7206	2.18651056574e-06
ko04911	Insulin secretion	23/532	117/7206	1.13944357329e-05
ko05030	Cocaine addiction	16/532	73/7206	6.29025488759e-05
ko04713	Circadian entrainment	24/532	136/7206	7.48013037281e-05
ko04391	Hippo signaling pathway - fly	18/532	90/7206	8.03232629752e-05
ko05203	Viral carcinogenesis	6/532	277/7206	0.000227308141917
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/532	14/7206	0.000283052759254
ko04010	MAPK signaling pathway	41/532	321/7206	0.000432755064657
ko03013	RNA transport	2/532	166/7206	0.000454595295997
ko04261	Adrenergic signaling in cardiomyocytes	29/532	205/7206	0.000593172859431
ko05031	Amphetamine addiction	16/532	91/7206	0.000897819607896
ko04744	Phototransduction	9/532	36/7206	0.000942279197646
ko04621	NOD-like receptor signaling pathway	2/532	157/7206	0.000961180356731
ko04217	Necroptosis	3/532	178/7206	0.00118828446387
ko04512	ECM-receptor interaction	14/532	79/7206	0.00171005671755
ko04726	Serotonergic synapse	20/532	137/7206	0.00271100887775
ko00240	Pyrimidine metabolism	1/532	110/7206	0.00472713809473
ko01200	Carbon metabolism	2/532	128/7206	0.00576212506633
ko04550	Signaling pathways regulating pluripotency of stem cells	22/532	165/7206	0.00609327099731
ko05322	Systemic lupus erythematosus	3/532	151/7206	0.0066792144534
ko00230	Purine metabolism	5/532	194/7206	0.00740117780677
ko04141	Protein processing in endoplasmic reticulum	5/532	184/7206	0.00970520328469
ko00564	Glycerophospholipid metabolism	1/532	99/7206	0.0100021296027
ko04146	Peroxisome	1/532	89/7206	0.0138218078488
ko04921	Oxytocin signaling pathway	25/532	209/7206	0.0150108267761
ko04390	Hippo signaling pathway	23/532	188/7206	0.0153751348505
ko05217	Basal cell carcinoma	11/532	68/7206	0.0157024607149
ko05205	Proteoglycans in cancer	10/532	271/7206	0.0170637738281
ko03018	RNA degradation	1/532	84/7206	0.020066623513
ko04915	Estrogen signaling pathway	17/532	131/7206	0.0260271800865
ko05168	Herpes simplex infection	6/532	182/7206	0.0303256524648
ko04962	Vasopressin-regulated water reabsorption	9/532	58/7206	0.0366195512056
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/532	59/7206	0.0384258944852
ko00010	Glycolysis / Gluconeogenesis	1/532	74/7206	0.0422258817552
ko04144	Endocytosis	35/532	342/7206	0.0438188238795
ko04612	Antigen processing and presentation	1/532	77/7206	0.0439872909462
ko04120	Ubiquitin mediated proteolysis	4/532	138/7206	0.046164060146
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11/532	79/7206	0.0462544007084
ko04151	PI3K-Akt signaling pathway	39/532	390/7206	0.046319100754
ko04064	NF-kappa B signaling pathway	2/532	96/7206	0.0467112654167
ko04060	Cytokine-cytokine receptor interaction	7/532	191/7206	0.0483265206177