ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04070	Phosphatidylinositol signaling system	32/512	112/7206	3.42456134091e-12
ko04720	Long-term potentiation	26/512	99/7206	2.8535651792e-09
ko04724	Glutamatergic synapse	33/512	152/7206	4.28936853e-09
ko04713	Circadian entrainment	30/512	136/7206	1.49755028605e-08
ko04921	Oxytocin signaling pathway	38/512	209/7206	5.01658891397e-08
ko04020	Calcium signaling pathway	44/512	265/7206	7.32440228123e-08
ko04080	Neuroactive ligand-receptor interaction	60/512	423/7206	1.39410318004e-07
ko04710	Circadian rhythm	14/512	43/7206	8.03338027651e-07
ko04925	Aldosterone synthesis and secretion	22/512	105/7206	3.21732642098e-06
ko05031	Amphetamine addiction	20/512	91/7206	4.1660893846e-06
ko05032	Morphine addiction	22/512	110/7206	7.18204876964e-06
ko04970	Salivary secretion	20/512	95/7206	8.34420982011e-06
ko00562	Inositol phosphate metabolism	19/512	89/7206	1.13335944381e-05
ko00051	Fructose and mannose metabolism	12/512	42/7206	2.24060728794e-05
ko04911	Insulin secretion	21/512	117/7206	6.35640916077e-05
ko04922	Glucagon signaling pathway	22/512	128/7206	8.42614341288e-05
ko04730	Long-term depression	16/512	78/7206	9.25141393073e-05
ko05033	Nicotine addiction	13/512	56/7206	0.000111876259391
ko04728	Dopaminergic synapse	28/512	185/7206	0.000116219359235
ko04727	GABAergic synapse	19/512	110/7206	0.000237458647885
ko04726	Serotonergic synapse	22/512	137/7206	0.000272080462167
ko00680	Methane metabolism	9/512	34/7206	0.000452249271261
ko03040	Spliceosome	1/512	145/7206	0.000457385599579
ko04072	Phospholipase D signaling pathway	27/512	197/7206	0.000983494480443
ko04750	Inflammatory mediator regulation of TRP channels	19/512	122/7206	0.00102139657614
ko04022	cGMP-PKG signaling pathway	29/512	216/7206	0.00103174124938
ko04745	Phototransduction - fly	9/512	38/7206	0.00108892885837
ko03010	Ribosome	1/512	129/7206	0.00146243668174
ko04261	Adrenergic signaling in cardiomyocytes	27/512	205/7206	0.00204438049589
ko01230	Biosynthesis of amino acids	14/512	85/7206	0.002442452279
ko04971	Gastric acid secretion	15/512	98/7206	0.00431436329462
ko00561	Glycerolipid metabolism	11/512	63/7206	0.00437207455849
ko00564	Glycerophospholipid metabolism	15/512	99/7206	0.00464039271455
ko05168	Herpes simplex infection	4/512	182/7206	0.00510199507066
ko00010	Glycolysis / Gluconeogenesis	12/512	74/7206	0.0055340276973
ko05230	Central carbon metabolism in cancer	13/512	81/7206	0.00680468679674
ko04152	AMPK signaling pathway	21/512	161/7206	0.00730925755637
ko04213	Longevity regulating pathway - multiple species	13/512	86/7206	0.00897037513569
ko04924	Renin secretion	13/512	86/7206	0.00897037513569
ko05322	Systemic lupus erythematosus	3/512	151/7206	0.00940879354886
ko05231	Choline metabolism in cancer	18/512	134/7206	0.00941782718154
ko04520	Adherens junction	1/512	103/7206	0.0101272819041
ko04723	Retrograde endocannabinoid signaling	22/512	175/7206	0.0102153084585
ko05200	Pathways in cancer	21/512	492/7206	0.0105599587272
ko04711	Circadian rhythm - fly	4/512	13/7206	0.0107432605728
ko00120	Primary bile acid biosynthesis	5/512	20/7206	0.0112601840965
ko04725	Cholinergic synapse	20/512	160/7206	0.0119336243764
ko05169	Epstein-Barr virus infection	6/512	206/7206	0.0128676388825
ko04721	Synaptic vesicle cycle	12/512	80/7206	0.0129814571217
ko04110	Cell cycle	3/512	145/7206	0.0130850571662
ko04138	Autophagy - yeast	12/512	81/7206	0.0138314462582
ko04915	Estrogen signaling pathway	17/512	131/7206	0.0146946739587
ko05203	Viral carcinogenesis	10/512	277/7206	0.0168681551651
ko02010	ABC transporters	7/512	39/7206	0.0184425690308
ko05014	Amyotrophic lateral sclerosis (ALS)	11/512	74/7206	0.0188371467522
ko04211	Longevity regulating pathway	16/512	123/7206	0.019104093886
ko04918	Thyroid hormone synthesis	12/512	86/7206	0.0195278310526
ko04960	Aldosterone-regulated sodium reabsorption	7/512	41/7206	0.0238637788005
ko00220	Arginine biosynthesis	5/512	24/7206	0.0244229337443
ko05214	Glioma	11/512	79/7206	0.025958036788
ko04260	Cardiac muscle contraction	13/512	98/7206	0.026663831489
ko00471	D-Glutamine and D-glutamate metabolism	2/512	4/7206	0.0274569317196
ko01040	Biosynthesis of unsaturated fatty acids	5/512	25/7206	0.0288015035876
ko05202	Transcriptional misregulation in cancer	6/512	188/7206	0.0304113958763
ko04060	Cytokine-cytokine receptor interaction	6/512	191/7206	0.0308161953811
ko04919	Thyroid hormone signaling pathway	17/512	143/7206	0.0316399052088
ko04350	TGF-beta signaling pathway	2/512	103/7206	0.0330866864123
ko04626	Plant-pathogen interaction	4/512	18/7206	0.0346785855716
ko04270	Vascular smooth muscle contraction	18/512	154/7206	0.037046445955
ko05030	Cocaine addiction	10/512	73/7206	0.0371163694357
ko04972	Pancreatic secretion	14/512	111/7206	0.0371459052185
ko04742	Taste transduction	9/512	61/7206	0.0381194688426
ko00592	alpha-Linolenic acid metabolism	4/512	19/7206	0.0415375935036
ko04024	cAMP signaling pathway	29/512	279/7206	0.0420292697588
ko04512	ECM-receptor interaction	1/512	79/7206	0.0434692234582
ko04137	Mitophagy - animal	11/512	82/7206	0.0464170554619
ko05162	Measles	3/512	120/7206	0.0470956053416
ko00250	Alanine, aspartate and glutamate metabolism	6/512	38/7206	0.0494771904945