ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	59/496	152/7206	2.32193060974e-30
ko05033	Nicotine addiction	33/496	56/7206	1.14810531828e-24
ko04080	Neuroactive ligand-receptor interaction	87/496	423/7206	8.60536004432e-22
ko04723	Retrograde endocannabinoid signaling	52/496	175/7206	1.3235804955e-20
ko05032	Morphine addiction	41/496	110/7206	1.5115431349e-20
ko04728	Dopaminergic synapse	51/496	185/7206	1.20873772804e-18
ko04727	GABAergic synapse	38/496	110/7206	8.4258407725e-18
ko04713	Circadian entrainment	42/496	136/7206	1.66665481503e-17
ko05031	Amphetamine addiction	28/496	91/7206	5.14737175125e-12
ko04024	cAMP signaling pathway	51/496	279/7206	5.69106996933e-11
ko05030	Cocaine addiction	23/496	73/7206	2.50329911668e-10
ko04020	Calcium signaling pathway	48/496	265/7206	3.02732843241e-10
ko04725	Cholinergic synapse	35/496	160/7206	4.88638428575e-10
ko04720	Long-term potentiation	26/496	99/7206	1.44583053994e-09
ko04742	Taste transduction	20/496	61/7206	1.71427468459e-09
ko04911	Insulin secretion	28/496	117/7206	3.33103375128e-09
ko04721	Synaptic vesicle cycle	22/496	80/7206	1.07440986195e-08
ko04261	Adrenergic signaling in cardiomyocytes	37/496	205/7206	4.02898980606e-08
ko04921	Oxytocin signaling pathway	37/496	209/7206	6.8104095556e-08
ko04726	Serotonergic synapse	28/496	137/7206	1.30457847518e-07
ko04915	Estrogen signaling pathway	26/496	131/7206	6.73267974965e-07
ko04925	Aldosterone synthesis and secretion	22/496	105/7206	1.90098669063e-06
ko04010	MAPK signaling pathway	45/496	321/7206	4.04291709697e-06
ko04072	Phospholipase D signaling pathway	31/496	197/7206	1.11243775837e-05
ko04740	Olfactory transduction	17/496	80/7206	2.31509100032e-05
ko05203	Viral carcinogenesis	4/496	277/7206	3.0022043646e-05
ko04060	Cytokine-cytokine receptor interaction	1/496	191/7206	3.07199943248e-05
ko05414	Dilated cardiomyopathy	20/496	112/7206	6.55074639516e-05
ko04514	Cell adhesion molecules (CAMs)	22/496	130/7206	6.67750393471e-05
ko04970	Salivary secretion	18/496	95/7206	6.78385688538e-05
ko04745	Phototransduction - fly	10/496	38/7206	0.000177849438601
ko04022	cGMP-PKG signaling pathway	30/496	216/7206	0.000183330767199
ko04360	Axon guidance	30/496	233/7206	0.000835084922284
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/496	79/7206	0.000869420084137
ko03013	RNA transport	2/496	166/7206	0.000968144320411
ko04971	Gastric acid secretion	16/496	98/7206	0.000969440699229
ko04371	Apelin signaling pathway	24/496	177/7206	0.00129497631082
ko04972	Pancreatic secretion	17/496	111/7206	0.00176284641771
ko04912	GnRH signaling pathway	18/496	122/7206	0.00176541526886
ko04211	Longevity regulating pathway	18/496	123/7206	0.0019136892913
ko04730	Long-term depression	13/496	78/7206	0.00234412031989
ko05034	Alcoholism	29/496	238/7206	0.00244005917283
ko04744	Phototransduction	8/496	36/7206	0.00258443529809
ko04670	Leukocyte transendothelial migration	2/496	151/7206	0.00291822438463
ko04930	Type II diabetes mellitus	10/496	54/7206	0.00333080213673
ko05014	Amyotrophic lateral sclerosis (ALS)	12/496	74/7206	0.00429497862201
ko04923	Regulation of lipolysis in adipocytes	12/496	77/7206	0.00596383908042
ko00513	Various types of N-glycan biosynthesis	8/496	42/7206	0.00700969440547
ko05168	Herpes simplex infection	4/496	182/7206	0.00709808864954
ko04540	Gap junction	17/496	128/7206	0.00754212284283
ko04213	Longevity regulating pathway - multiple species	13/496	86/7206	0.00768530545785
ko04630	Jak-STAT signaling pathway	2/496	132/7206	0.00837084287058
ko05410	Hypertrophic cardiomyopathy (HCM)	14/496	100/7206	0.00895155801437
ko04350	TGF-beta signaling pathway	1/496	103/7206	0.00969042413418
ko04070	Phosphatidylinositol signaling system	15/496	112/7206	0.0124763385665
ko00512	Mucin type O-glycan biosynthesis	6/496	29/7206	0.0125756572842
ko04110	Cell cycle	3/496	145/7206	0.0185772576915
ko04012	ErbB signaling pathway	14/496	109/7206	0.0205405603374
ko04976	Bile secretion	11/496	80/7206	0.0236102186409
ko04260	Cardiac muscle contraction	13/496	98/7206	0.0236469443761
ko04621	NOD-like receptor signaling pathway	4/496	157/7206	0.0249435458831
ko00515	Mannose type O-glycan biosynthesis	5/496	25/7206	0.0255043474807
ko04750	Inflammatory mediator regulation of TRP channels	15/496	122/7206	0.0278219225625
ko04062	Chemokine signaling pathway	22/496	201/7206	0.0323041103944
ko05322	Systemic lupus erythematosus	4/496	151/7206	0.0338495763066
ko00240	Pyrimidine metabolism	2/496	110/7206	0.0340418514404
ko05205	Proteoglycans in cancer	10/496	271/7206	0.0364326558122
ko04114	Oocyte meiosis	16/496	139/7206	0.0401541451538
ko03008	Ribosome biogenesis in eukaryotes	1/496	79/7206	0.042620988325
ko04918	Thyroid hormone synthesis	11/496	86/7206	0.0484964228969
ko05169	Epstein-Barr virus infection	7/496	206/7206	0.0489897568634