ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	87/738	145/7206	4.46493850329e-50
ko04110	Cell cycle	61/738	145/7206	5.34577168152e-24
ko04111	Cell cycle - yeast	46/738	90/7206	1.05051939989e-22
ko03030	DNA replication	29/738	38/7206	7.99536601671e-22
ko04080	Neuroactive ligand-receptor interaction	1/738	423/7206	2.90599078587e-19
ko03013	RNA transport	58/738	166/7206	3.39479184496e-18
ko03008	Ribosome biogenesis in eukaryotes	38/738	79/7206	8.7357874904e-18
ko04113	Meiosis - yeast	31/738	70/7206	1.68098899484e-13
ko03460	Fanconi anemia pathway	25/738	51/7206	2.29342812404e-12
ko00240	Pyrimidine metabolism	38/738	110/7206	3.78053976035e-12
ko03410	Base excision repair	21/738	38/7206	6.70160191061e-12
ko03015	mRNA surveillance pathway	34/738	93/7206	8.53547977823e-12
ko03430	Mismatch repair	15/738	22/7206	1.07325606069e-10
ko04020	Calcium signaling pathway	2/738	265/7206	1.7358657257e-10
ko04144	Endocytosis	7/738	342/7206	2.50773290891e-09
ko03420	Nucleotide excision repair	20/738	46/7206	5.33919270155e-09
ko03020	RNA polymerase	14/738	29/7206	2.21432029775e-07
ko04060	Cytokine-cytokine receptor interaction	2/738	191/7206	3.67759382623e-07
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/738	182/7206	1.28239949483e-06
ko04724	Glutamatergic synapse	1/738	152/7206	2.14099802151e-06
ko04921	Oxytocin signaling pathway	4/738	209/7206	3.98999827116e-06
ko00230	Purine metabolism	41/738	194/7206	5.46241790457e-06
ko03440	Homologous recombination	15/738	41/7206	6.14705723151e-06
ko04062	Chemokine signaling pathway	4/738	201/7206	8.33857021805e-06
ko04022	cGMP-PKG signaling pathway	5/738	216/7206	1.04070613757e-05
ko04024	cAMP signaling pathway	9/738	279/7206	1.18246757015e-05
ko04723	Retrograde endocannabinoid signaling	3/738	175/7206	1.26629051164e-05
ko04725	Cholinergic synapse	3/738	160/7206	5.63469390417e-05
ko04072	Phospholipase D signaling pathway	5/738	197/7206	6.27413287555e-05
ko04726	Serotonergic synapse	2/738	137/7206	8.62355722222e-05
ko05217	Basal cell carcinoma	18/738	68/7206	0.000114016205705
ko04070	Phosphatidylinositol signaling system	1/738	112/7206	0.000116193491482
ko05414	Dilated cardiomyopathy	1/738	112/7206	0.000116193491482
ko04270	Vascular smooth muscle contraction	3/738	154/7206	0.000122271626743
ko04727	GABAergic synapse	1/738	110/7206	0.000178616234104
ko03010	Ribosome	2/738	129/7206	0.000184106802155
ko04915	Estrogen signaling pathway	2/738	131/7206	0.000194815262272
ko05169	Epstein-Barr virus infection	38/738	206/7206	0.00026306939879
ko04510	Focal adhesion	9/738	240/7206	0.000299968571582
ko03018	RNA degradation	20/738	84/7206	0.000343909520802
ko04014	Ras signaling pathway	12/738	279/7206	0.000375364488447
ko05410	Hypertrophic cardiomyopathy (HCM)	1/738	100/7206	0.00038045645537
ko04912	GnRH signaling pathway	2/738	122/7206	0.000399023435819
ko04621	NOD-like receptor signaling pathway	4/738	157/7206	0.00043207941611
ko04974	Protein digestion and absorption	1/738	96/7206	0.000563984277754
ko04260	Cardiac muscle contraction	1/738	98/7206	0.000578027481436
ko04971	Gastric acid secretion	1/738	98/7206	0.000578027481436
ko04630	Jak-STAT signaling pathway	3/738	132/7206	0.000721424462177
ko05166	HTLV-I infection	48/738	292/7206	0.00076071458517
ko03050	Proteasome	14/738	54/7206	0.000809949522583
ko04970	Salivary secretion	1/738	95/7206	0.000882004593921
ko04010	MAPK signaling pathway	16/738	321/7206	0.000898647141867
ko04371	Apelin signaling pathway	6/738	177/7206	0.000978267525472
ko05032	Morphine addiction	2/738	110/7206	0.00121917382122
ko00562	Inositol phosphate metabolism	1/738	89/7206	0.00123885691928
ko04340	Hedgehog signaling pathway	14/738	58/7206	0.00171978613752
ko04015	Rap1 signaling pathway	14/738	278/7206	0.00231920703019
ko04380	Osteoclast differentiation	4/738	134/7206	0.00233209910274
ko05231	Choline metabolism in cancer	4/738	134/7206	0.00233209910274
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/738	135/7206	0.00233867336869
ko04713	Circadian entrainment	4/738	136/7206	0.00236548815067
ko04620	Toll-like receptor signaling pathway	2/738	100/7206	0.0024861089745
ko04810	Regulation of actin cytoskeleton	13/738	264/7206	0.0025212589897
ko04911	Insulin secretion	3/738	117/7206	0.00300998952312
ko04261	Adrenergic signaling in cardiomyocytes	9/738	205/7206	0.0032340430825
ko04722	Neurotrophin signaling pathway	6/738	160/7206	0.00347616440951
ko05211	Renal cell carcinoma	2/738	96/7206	0.00358433153108
ko04720	Long-term potentiation	2/738	99/7206	0.00377359493024
ko00564	Glycerophospholipid metabolism	2/738	99/7206	0.00377359493024
ko05146	Amoebiasis	2/738	99/7206	0.00377359493024
ko04730	Long-term depression	1/738	78/7206	0.00402639662655
ko04610	Complement and coagulation cascades	1/738	79/7206	0.00413470937462
ko04972	Pancreatic secretion	3/738	111/7206	0.00418882058182
ko04330	Notch signaling pathway	14/738	62/7206	0.00454907319714
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/738	92/7206	0.00515657946968
ko04750	Inflammatory mediator regulation of TRP channels	4/738	122/7206	0.00632675650599
ko04670	Leukocyte transendothelial migration	6/738	151/7206	0.00644142796134
ko04931	Insulin resistance	5/738	137/7206	0.00648120509976
ko04611	Platelet activation	7/738	163/7206	0.00845698918326
ko04925	Aldosterone synthesis and secretion	3/738	105/7206	0.00849046255605
ko04659	Th17 cell differentiation	3/738	106/7206	0.00868164634937
ko04151	PI3K-Akt signaling pathway	25/738	390/7206	0.00970350488632
ko04530	Tight junction	12/738	228/7206	0.0101999013039
ko04910	Insulin signaling pathway	8/738	172/7206	0.0106316048476
ko04924	Renin secretion	2/738	86/7206	0.0108481233074
ko04540	Gap junction	5/738	128/7206	0.0120993706003
ko04612	Antigen processing and presentation	15/738	77/7206	0.0126540003673
ko04728	Dopaminergic synapse	9/738	185/7206	0.0132774572306
ko05202	Transcriptional misregulation in cancer	30/738	188/7206	0.0140182317605
ko05160	Hepatitis C	7/738	153/7206	0.0150130812016
ko04740	Olfactory transduction	2/738	80/7206	0.0151339012941
ko04138	Autophagy - yeast	2/738	81/7206	0.0152416535438
ko05145	Toxoplasmosis	5/738	126/7206	0.0166340077214
ko05110	Vibrio cholerae infection	1/738	63/7206	0.0190475453223
ko00561	Glycerolipid metabolism	1/738	63/7206	0.0190475453223
ko00600	Sphingolipid metabolism	1/738	63/7206	0.0190475453223
ko04640	Hematopoietic cell lineage	1/738	64/7206	0.0196824239568
ko04370	VEGF signaling pathway	2/738	77/7206	0.0217116778556
ko04664	Fc epsilon RI signaling pathway	2/738	77/7206	0.0217116778556
ko04120	Ubiquitin mediated proteolysis	23/738	138/7206	0.0219304128078
ko04668	TNF signaling pathway	5/738	120/7206	0.0222646564101
ko04114	Oocyte meiosis	23/738	139/7206	0.0223858190233
ko05031	Amphetamine addiction	3/738	91/7206	0.0228162955439
ko04961	Endocrine and other factor-regulated calcium reabsorption	1/738	59/7206	0.0278030299382
ko05142	Chagas disease (American trypanosomiasis)	6/738	130/7206	0.0283036872622
ko04514	Cell adhesion molecules (CAMs)	6/738	130/7206	0.0283036872622
ko05030	Cocaine addiction	2/738	73/7206	0.0308344266617
ko04213	Longevity regulating pathway - multiple species	3/738	86/7206	0.0316756427098
ko04917	Prolactin signaling pathway	3/738	87/7206	0.0317084105319
ko04922	Glucagon signaling pathway	6/738	128/7206	0.0379806135656
ko03022	Basal transcription factors	9/738	44/7206	0.040100938088
ko05168	Herpes simplex infection	27/738	182/7206	0.0466157088128
ko00670	One carbon pool by folate	5/738	20/7206	0.0468968509498
ko04350	TGF-beta signaling pathway	17/738	103/7206	0.0472046544069
ko04071	Sphingolipid signaling pathway	9/738	162/7206	0.0483776083522
ko04666	Fc gamma R-mediated phagocytosis	6/738	122/7206	0.0497124322718
ko04550	Signaling pathways regulating pluripotency of stem cells	25/738	165/7206	0.0497501745186
ko04066	HIF-1 signaling pathway	6/738	123/7206	0.0499070043748