ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	173/1017	423/7206	7.30210364912e-45
ko04724	Glutamatergic synapse	78/1017	152/7206	3.82534227474e-28
ko05033	Nicotine addiction	43/1017	56/7206	3.70275769572e-26
ko05032	Morphine addiction	57/1017	110/7206	4.23904244751e-21
ko04728	Dopaminergic synapse	76/1017	185/7206	6.718018601e-20
ko04713	Circadian entrainment	61/1017	136/7206	1.94579304289e-18
ko04727	GABAergic synapse	53/1017	110/7206	7.18460557881e-18
ko04725	Cholinergic synapse	65/1017	160/7206	7.0989264036e-17
ko04024	cAMP signaling pathway	92/1017	279/7206	2.51061109561e-16
ko04721	Synaptic vesicle cycle	42/1017	80/7206	3.94420208076e-16
ko04020	Calcium signaling pathway	88/1017	265/7206	7.67269534422e-16
ko04723	Retrograde endocannabinoid signaling	65/1017	175/7206	1.30498830952e-14
ko04911	Insulin secretion	50/1017	117/7206	2.70275724776e-14
ko04726	Serotonergic synapse	54/1017	137/7206	1.43295079407e-13
ko04921	Oxytocin signaling pathway	68/1017	209/7206	5.16598255153e-12
ko04742	Taste transduction	30/1017	61/7206	5.92319089517e-11
ko05031	Amphetamine addiction	38/1017	91/7206	8.26118855781e-11
ko03040	Spliceosome	1/1017	145/7206	9.02806254298e-09
ko04720	Long-term potentiation	36/1017	99/7206	2.21767298329e-08
ko04261	Adrenergic signaling in cardiomyocytes	59/1017	205/7206	3.27482898405e-08
ko04744	Phototransduction	19/1017	36/7206	4.70043878408e-08
ko05322	Systemic lupus erythematosus	3/1017	151/7206	3.8562577679e-07
ko04925	Aldosterone synthesis and secretion	35/1017	105/7206	5.14436113745e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1017	74/7206	1.18664217479e-06
ko04970	Salivary secretion	32/1017	95/7206	1.46864457031e-06
ko04360	Axon guidance	60/1017	233/7206	1.9369990701e-06
ko03013	RNA transport	5/1017	166/7206	2.38598091295e-06
ko04120	Ubiquitin mediated proteolysis	3/1017	138/7206	2.81137970236e-06
ko04070	Phosphatidylinositol signaling system	35/1017	112/7206	2.97314524785e-06
ko05030	Cocaine addiction	26/1017	73/7206	3.15819343704e-06
ko04010	MAPK signaling pathway	75/1017	321/7206	5.30080112062e-06
ko04514	Cell adhesion molecules (CAMs)	38/1017	130/7206	5.73638791094e-06
ko04971	Gastric acid secretion	31/1017	98/7206	6.81993596415e-06
ko05168	Herpes simplex infection	7/1017	182/7206	7.0336807932e-06
ko05203	Viral carcinogenesis	16/1017	277/7206	1.30555986812e-05
ko04621	NOD-like receptor signaling pathway	6/1017	157/7206	3.67932696227e-05
ko04141	Protein processing in endoplasmic reticulum	9/1017	184/7206	9.06393248286e-05
ko04745	Phototransduction - fly	15/1017	38/7206	0.00010132012297
ko04730	Long-term depression	24/1017	78/7206	0.000122324384045
ko03008	Ribosome biogenesis in eukaryotes	1/1017	79/7206	0.000129450968021
ko04022	cGMP-PKG signaling pathway	51/1017	216/7206	0.000141556520333
ko05164	Influenza A	8/1017	167/7206	0.000168156335757
ko04750	Inflammatory mediator regulation of TRP channels	33/1017	122/7206	0.000179363527767
ko04612	Antigen processing and presentation	1/1017	77/7206	0.000197776840686
ko04014	Ras signaling pathway	62/1017	279/7206	0.000204948047239
ko04972	Pancreatic secretion	30/1017	111/7206	0.000288829997557
ko04964	Proximal tubule bicarbonate reclamation	12/1017	29/7206	0.000298129628428
ko04966	Collecting duct acid secretion	11/1017	26/7206	0.00042341270855
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1017	79/7206	0.000473778372852
ko04710	Circadian rhythm	15/1017	43/7206	0.000498355967764
ko04740	Olfactory transduction	23/1017	80/7206	0.000550010350907
ko04072	Phospholipase D signaling pathway	45/1017	197/7206	0.000814463810252
ko04260	Cardiac muscle contraction	26/1017	98/7206	0.00108326882131
ko04110	Cell cycle	8/1017	145/7206	0.0015437269899
ko04146	Peroxisome	3/1017	89/7206	0.00178910401834
ko04626	Plant-pathogen interaction	8/1017	18/7206	0.00179781107604
ko04540	Gap junction	31/1017	128/7206	0.00191922392565
ko04060	Cytokine-cytokine receptor interaction	13/1017	191/7206	0.00211103836112
ko00562	Inositol phosphate metabolism	23/1017	89/7206	0.00312864085666
ko04915	Estrogen signaling pathway	31/1017	131/7206	0.00322748561655
ko04924	Renin secretion	22/1017	86/7206	0.00443740996532
ko04960	Aldosterone-regulated sodium reabsorption	13/1017	41/7206	0.00503109375208
ko05205	Proteoglycans in cancer	23/1017	271/7206	0.00563982070652
ko05110	Vibrio cholerae infection	17/1017	63/7206	0.00596453468867
ko05169	Epstein-Barr virus infection	16/1017	206/7206	0.00596871534868
ko05140	Leishmaniasis	3/1017	75/7206	0.00712718568965
ko05162	Measles	7/1017	120/7206	0.0075184747663
ko04064	NF-kappa B signaling pathway	5/1017	96/7206	0.00763840267462
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1017	14/7206	0.00849259167578
ko05414	Dilated cardiomyopathy	26/1017	112/7206	0.00874973959483
ko04976	Bile secretion	20/1017	80/7206	0.00886178514926
ko00330	Arginine and proline metabolism	2/1017	61/7206	0.00912656547538
ko04330	Notch signaling pathway	2/1017	62/7206	0.00921808341811
ko04214	Apoptosis - fly	3/1017	72/7206	0.0101189191096
ko00260	Glycine, serine and threonine metabolism	1/1017	48/7206	0.0110062583361
ko05219	Bladder cancer	1/1017	48/7206	0.0110062583361
ko04630	Jak-STAT signaling pathway	9/1017	132/7206	0.011480659673
ko04217	Necroptosis	14/1017	178/7206	0.0121314721733
ko04973	Carbohydrate digestion and absorption	12/1017	42/7206	0.012665422766
ko05166	HTLV-I infection	27/1017	292/7206	0.0127464845304
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1017	100/7206	0.0137850730989
ko03022	Basal transcription factors	1/1017	44/7206	0.0161493553751
ko05144	Malaria	1/1017	45/7206	0.0162987214394
ko00071	Fatty acid degradation	1/1017	45/7206	0.0162987214394
ko05231	Choline metabolism in cancer	29/1017	134/7206	0.0166203145233
ko03420	Nucleotide excision repair	1/1017	46/7206	0.0168426024777
ko04930	Type II diabetes mellitus	14/1017	54/7206	0.0179564928489
ko05161	Hepatitis B	14/1017	173/7206	0.0198328182577
ko05145	Toxoplasmosis	9/1017	126/7206	0.0199200766906
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1017	59/7206	0.0218215500942
ko05016	Huntington's disease	19/1017	215/7206	0.0220036653441
ko00590	Arachidonic acid metabolism	2/1017	52/7206	0.0273062430698
ko04015	Rap1 signaling pathway	52/1017	278/7206	0.0280308672503
ko04115	p53 signaling pathway	4/1017	74/7206	0.0280892005917
ko00280	Valine, leucine and isoleucine degradation	2/1017	54/7206	0.0282314643921
ko04922	Glucagon signaling pathway	27/1017	128/7206	0.02864996155
ko04640	Hematopoietic cell lineage	3/1017	64/7206	0.0286714704951
ko03410	Base excision repair	1/1017	38/7206	0.0353525319178
ko04962	Vasopressin-regulated water reabsorption	14/1017	58/7206	0.0359891252398
ko04622	RIG-I-like receptor signaling pathway	3/1017	62/7206	0.041083457125
ko04610	Complement and coagulation cascades	5/1017	79/7206	0.0495730618311