ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 26/246 79/7206 2.05709189771e-19 ko04510 Focal adhesion 37/246 240/7206 4.17399273445e-15 ko04974 Protein digestion and absorption 22/246 96/7206 5.96202903743e-13 ko04151 PI3K-Akt signaling pathway 39/246 390/7206 7.99016485901e-10 ko05410 Hypertrophic cardiomyopathy (HCM) 17/246 100/7206 3.53340531843e-08 ko05205 Proteoglycans in cancer 28/246 271/7206 1.24483572467e-07 ko04810 Regulation of actin cytoskeleton 27/246 264/7206 2.62035366886e-07 ko04668 TNF signaling pathway 17/246 120/7206 5.47196021533e-07 ko05414 Dilated cardiomyopathy 16/246 112/7206 1.06163781144e-06 ko05146 Amoebiasis 14/246 99/7206 5.75030337328e-06 ko04933 AGE-RAGE signaling pathway in diabetic complications 16/246 135/7206 1.27401566163e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/246 79/7206 1.28531875475e-05 ko05200 Pathways in cancer 36/246 492/7206 1.31533386945e-05 ko04060 Cytokine-cytokine receptor interaction 19/246 191/7206 2.51963131343e-05 ko05131 Shigellosis 11/246 82/7206 9.61901575047e-05 ko05144 Malaria 8/246 45/7206 0.000118662297465 ko05133 Pertussis 11/246 87/7206 0.000165495120575 ko05120 Epithelial cell signaling in Helicobacter pylori infection 10/246 92/7206 0.00110169879363 ko04670 Leukocyte transendothelial migration 13/246 151/7206 0.00188928305969 ko05100 Bacterial invasion of epithelial cells 10/246 99/7206 0.00193254130094 ko05224 Breast cancer 14/246 174/7206 0.00242376182711 ko04912 GnRH signaling pathway 11/246 122/7206 0.00290318150083 ko04666 Fc gamma R-mediated phagocytosis 11/246 122/7206 0.00290318150083 ko05222 Small cell lung cancer 9/246 89/7206 0.00319555251853 ko04916 Melanogenesis 12/246 142/7206 0.0032643720775 ko05034 Alcoholism 1/246 238/7206 0.00526228588348 ko05219 Bladder cancer 6/246 48/7206 0.00549291158789 ko04640 Hematopoietic cell lineage 7/246 64/7206 0.00586741073195 ko04380 Osteoclast differentiation 11/246 134/7206 0.00594554796562 ko05132 Salmonella infection 9/246 98/7206 0.00607107880574 ko05166 HTLV-I infection 19/246 292/7206 0.00727187232733 ko05206 MicroRNAs in cancer 13/246 177/7206 0.00935877283994 ko04657 IL-17 signaling pathway 8/246 87/7206 0.00940829806832 ko05145 Toxoplasmosis 10/246 126/7206 0.0107400833904 ko05134 Legionellosis 7/246 74/7206 0.0127613704201 ko05142 Chagas disease (American trypanosomiasis) 10/246 130/7206 0.0131994117149 ko04390 Hippo signaling pathway 13/246 188/7206 0.0132752388004 ko05140 Leishmaniasis 7/246 75/7206 0.0136786008105 ko04064 NF-kappa B signaling pathway 8/246 96/7206 0.0164534787117 ko04010 MAPK signaling pathway 19/246 321/7206 0.017341773865 ko04015 Rap1 signaling pathway 17/246 278/7206 0.0173799464756 ko04144 Endocytosis 20/246 342/7206 0.0203589489106 ko04210 Apoptosis 12/246 180/7206 0.0217977784295 ko04611 Platelet activation 11/246 163/7206 0.0266936574375 ko00760 Nicotinate and nicotinamide metabolism 4/246 34/7206 0.0275247569742 ko05217 Basal cell carcinoma 6/246 68/7206 0.0279372278858 ko05164 Influenza A 11/246 167/7206 0.0302496605895 ko05323 Rheumatoid arthritis 7/246 89/7206 0.0318893407409 ko04310 Wnt signaling pathway 12/246 181/7206 0.0337932756771 ko04660 T cell receptor signaling pathway 9/246 124/7206 0.0385817677239 ko05160 Hepatitis C 10/246 153/7206 0.0408466921558 ko05321 Inflammatory bowel disease (IBD) 5/246 56/7206 0.0414132077032 ko04514 Cell adhesion molecules (CAMs) 9/246 130/7206 0.0438792231263 ko04658 Th1 and Th2 cell differentiation 7/246 96/7206 0.0452680597459 ko03013 RNA transport 1/246 166/7206 0.046895569163 ko05130 Pathogenic Escherichia coli infection 6/246 77/7206 0.0471332272905