ko pathway ratio_in_study ratio_in_pop p_value ko05410 Hypertrophic cardiomyopathy (HCM) 21/196 100/7206 1.43344872183e-13 ko05414 Dilated cardiomyopathy 21/196 112/7206 1.51033282265e-12 ko04260 Cardiac muscle contraction 19/196 98/7206 9.97141520106e-12 ko04512 ECM-receptor interaction 17/196 79/7206 2.22045627701e-11 ko00020 Citrate cycle (TCA cycle) 11/196 35/7206 1.07469499751e-09 ko04510 Focal adhesion 25/196 240/7206 5.68943216814e-09 ko04261 Adrenergic signaling in cardiomyocytes 23/196 205/7206 5.85299848461e-09 ko05416 Viral myocarditis 12/196 55/7206 1.84397138886e-08 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/196 79/7206 2.00797986543e-08 ko04020 Calcium signaling pathway 25/196 265/7206 4.25545063689e-08 ko01200 Carbon metabolism 17/196 128/7206 5.29805205769e-08 ko04974 Protein digestion and absorption 14/196 96/7206 2.57164121201e-07 ko00620 Pyruvate metabolism 9/196 46/7206 3.12611757219e-06 ko04921 Oxytocin signaling pathway 19/196 209/7206 3.48215532451e-06 ko00010 Glycolysis / Gluconeogenesis 11/196 74/7206 4.25658107e-06 ko04022 cGMP-PKG signaling pathway 18/196 216/7206 2.12451537811e-05 ko04922 Glucagon signaling pathway 13/196 128/7206 4.07278999021e-05 ko00500 Starch and sucrose metabolism 6/196 35/7206 0.000315136362542 ko04151 PI3K-Akt signaling pathway 22/196 390/7206 0.00106004663741 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/196 135/7206 0.00107471544832 ko05144 Malaria 6/196 45/7206 0.00126188970801 ko05146 Amoebiasis 9/196 99/7206 0.00141864710648 ko05230 Central carbon metabolism in cancer 8/196 81/7206 0.00152605781821 ko04010 MAPK signaling pathway 18/196 321/7206 0.00394921230841 ko00710 Carbon fixation in photosynthetic organisms 4/196 27/7206 0.00570362646681 ko04371 Apelin signaling pathway 11/196 177/7206 0.00871838261743 ko04911 Insulin secretion 8/196 117/7206 0.0141501434413 ko04930 Type II diabetes mellitus 5/196 54/7206 0.0152116499935 ko05211 Renal cell carcinoma 7/196 96/7206 0.0153577866955 ko04912 GnRH signaling pathway 8/196 122/7206 0.0178264591607 ko00630 Glyoxylate and dicarboxylate metabolism 4/196 38/7206 0.0190342023406 ko05205 Proteoglycans in cancer 14/196 271/7206 0.0199703589883 ko05034 Alcoholism 1/196 238/7206 0.0227298643018 ko05010 Alzheimer's disease 11/196 202/7206 0.0251554295511 ko00051 Fructose and mannose metabolism 4/196 42/7206 0.026550027759 ko01230 Biosynthesis of amino acids 6/196 85/7206 0.0277850515622 ko04924 Renin secretion 6/196 86/7206 0.0292180759121 ko05203 Viral carcinogenesis 2/196 277/7206 0.035609765845 ko04062 Chemokine signaling pathway 1/196 201/7206 0.0454804820048