ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	52/671	152/7206	9.05369601152e-18
ko05032	Morphine addiction	43/671	110/7206	2.34139072269e-17
ko05033	Nicotine addiction	30/671	56/7206	4.09848118383e-17
ko04727	GABAergic synapse	42/671	110/7206	1.53303336679e-16
ko04723	Retrograde endocannabinoid signaling	51/671	175/7206	3.31372173852e-14
ko04713	Circadian entrainment	44/671	136/7206	3.33211612784e-14
ko04721	Synaptic vesicle cycle	32/671	80/7206	1.47365018836e-13
ko04728	Dopaminergic synapse	51/671	185/7206	3.73559612218e-13
ko04725	Cholinergic synapse	45/671	160/7206	4.49641397941e-12
ko04024	cAMP signaling pathway	62/671	279/7206	3.3428332419e-11
ko04080	Neuroactive ligand-receptor interaction	82/671	423/7206	4.00626358667e-11
ko04744	Phototransduction	18/671	36/7206	4.04639268339e-10
ko04911	Insulin secretion	32/671	117/7206	1.26533960918e-08
ko04261	Adrenergic signaling in cardiomyocytes	45/671	205/7206	2.9032626142e-08
ko04921	Oxytocin signaling pathway	45/671	209/7206	7.37245320149e-08
ko04726	Serotonergic synapse	33/671	137/7206	2.116753031e-07
ko04010	MAPK signaling pathway	55/671	321/7206	7.20019393431e-06
ko04970	Salivary secretion	23/671	95/7206	1.35356758878e-05
ko03040	Spliceosome	1/671	145/7206	1.71559211267e-05
ko04360	Axon guidance	41/671	233/7206	4.97203075434e-05
ko05322	Systemic lupus erythematosus	2/671	151/7206	9.28537180249e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/671	14/7206	0.00011261709416
ko05203	Viral carcinogenesis	9/671	277/7206	0.000122323491001
ko04072	Phospholipase D signaling pathway	35/671	197/7206	0.000154670649167
ko04514	Cell adhesion molecules (CAMs)	26/671	130/7206	0.000169518143149
ko04260	Cardiac muscle contraction	21/671	98/7206	0.000274721423003
ko04742	Taste transduction	15/671	61/7206	0.000353444467932
ko04020	Calcium signaling pathway	42/671	265/7206	0.000508716544949
ko03013	RNA transport	4/671	166/7206	0.000625524180854
ko05164	Influenza A	4/671	167/7206	0.000630880248663
ko04730	Long-term depression	17/671	78/7206	0.00067187156844
ko04972	Pancreatic secretion	22/671	111/7206	0.000704562940248
ko05031	Amphetamine addiction	19/671	91/7206	0.00071552964169
ko04720	Long-term potentiation	20/671	99/7206	0.00072246929196
ko04070	Phosphatidylinositol signaling system	22/671	112/7206	0.000751510162609
ko05030	Cocaine addiction	16/671	73/7206	0.00089869329467
ko04964	Proximal tubule bicarbonate reclamation	9/671	29/7206	0.000904826033249
ko04022	cGMP-PKG signaling pathway	35/671	216/7206	0.00115586463092
ko04966	Collecting duct acid secretion	8/671	26/7206	0.001854106827
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/671	79/7206	0.00259400472667
ko05168	Herpes simplex infection	6/671	182/7206	0.00266857091052
ko04960	Aldosterone-regulated sodium reabsorption	10/671	41/7206	0.00357288085963
ko05414	Dilated cardiomyopathy	20/671	112/7206	0.00448344086463
ko04621	NOD-like receptor signaling pathway	5/671	157/7206	0.00496178621051
ko04014	Ras signaling pathway	40/671	279/7206	0.00593046087457
ko04141	Protein processing in endoplasmic reticulum	7/671	184/7206	0.00651326919429
ko05205	Proteoglycans in cancer	13/671	271/7206	0.00737505998544
ko05140	Leishmaniasis	1/671	75/7206	0.00888312708581
ko04925	Aldosterone synthesis and secretion	18/671	105/7206	0.0100408579283
ko05169	Epstein-Barr virus infection	9/671	206/7206	0.0102364376841
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/671	59/7206	0.010270437804
ko04060	Cytokine-cytokine receptor interaction	8/671	191/7206	0.0110127154023
ko00240	Pyrimidine metabolism	3/671	110/7206	0.0121403289766
ko04071	Sphingolipid signaling pathway	25/671	162/7206	0.0128129126078
ko04973	Carbohydrate digestion and absorption	9/671	42/7206	0.0134935225563
ko05110	Vibrio cholerae infection	12/671	63/7206	0.0142732837624
ko04930	Type II diabetes mellitus	11/671	54/7206	0.0147876143694
ko04146	Peroxisome	2/671	89/7206	0.0156972422978
ko04120	Ubiquitin mediated proteolysis	5/671	138/7206	0.0170104638489
ko04371	Apelin signaling pathway	26/671	177/7206	0.0177567688046
ko04976	Bile secretion	14/671	80/7206	0.0184348734545
ko04540	Gap junction	20/671	128/7206	0.0200423902759
ko04971	Gastric acid secretion	16/671	98/7206	0.0222291503935
ko05014	Amyotrophic lateral sclerosis (ALS)	13/671	74/7206	0.0240084955576
ko00562	Inositol phosphate metabolism	15/671	89/7206	0.0249063699338
ko04217	Necroptosis	8/671	178/7206	0.025273148012
ko04640	Hematopoietic cell lineage	1/671	64/7206	0.0280448433387
ko04923	Regulation of lipolysis in adipocytes	13/671	77/7206	0.0290661734792
ko04510	Focal adhesion	13/671	240/7206	0.0317104905632
ko05215	Prostate cancer	4/671	111/7206	0.0320154645852
ko04064	NF-kappa B signaling pathway	3/671	96/7206	0.0325358679224
ko05410	Hypertrophic cardiomyopathy (HCM)	16/671	100/7206	0.034813994913
ko04918	Thyroid hormone synthesis	14/671	86/7206	0.0371819773599
ko00330	Arginine and proline metabolism	1/671	61/7206	0.04198918089
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/671	15/7206	0.0443052891586
ko04612	Antigen processing and presentation	2/671	77/7206	0.0453547795146
ko00290	Valine, leucine and isoleucine biosynthesis	2/671	4/7206	0.0457449115194
ko04915	Estrogen signaling pathway	19/671	131/7206	0.0473757631412
ko00512	Mucin type O-glycan biosynthesis	6/671	29/7206	0.0474299202143
ko04062	Chemokine signaling pathway	27/671	201/7206	0.0482132509539