ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	128/739	423/7206	2.23455278528e-32
ko04724	Glutamatergic synapse	63/739	152/7206	2.69220491442e-24
ko05033	Nicotine addiction	36/739	56/7206	1.20172782276e-22
ko04727	GABAergic synapse	45/739	110/7206	2.21779967201e-17
ko05032	Morphine addiction	45/739	110/7206	2.21779967201e-17
ko04723	Retrograde endocannabinoid signaling	58/739	175/7206	6.16673684897e-17
ko04728	Dopaminergic synapse	59/739	185/7206	2.52457776865e-16
ko04721	Synaptic vesicle cycle	36/739	80/7206	9.94080602559e-16
ko04713	Circadian entrainment	48/739	136/7206	2.02117894207e-15
ko04725	Cholinergic synapse	49/739	160/7206	5.43682463051e-13
ko04024	cAMP signaling pathway	68/739	279/7206	4.69717672235e-12
ko04020	Calcium signaling pathway	65/739	265/7206	7.73196633788e-12
ko04911	Insulin secretion	37/739	117/7206	1.45906138188e-10
ko04921	Oxytocin signaling pathway	51/739	209/7206	1.95012912736e-09
ko04726	Serotonergic synapse	38/739	137/7206	5.40595910856e-09
ko04261	Adrenergic signaling in cardiomyocytes	49/739	205/7206	1.22684550962e-08
ko05031	Amphetamine addiction	28/739	91/7206	5.06791026589e-08
ko04720	Long-term potentiation	29/739	99/7206	9.77703954468e-08
ko04970	Salivary secretion	28/739	95/7206	1.40907287263e-07
ko05322	Systemic lupus erythematosus	1/739	151/7206	2.11211483299e-06
ko04966	Collecting duct acid secretion	12/739	26/7206	3.07593888446e-06
ko04022	cGMP-PKG signaling pathway	45/739	216/7206	3.19110219274e-06
ko03040	Spliceosome	1/739	145/7206	4.93373137294e-06
ko04730	Long-term depression	22/739	78/7206	6.8588972155e-06
ko05030	Cocaine addiction	21/739	73/7206	7.88763228884e-06
ko04120	Ubiquitin mediated proteolysis	1/739	138/7206	1.13990687332e-05
ko04971	Gastric acid secretion	25/739	98/7206	1.1700185546e-05
ko04972	Pancreatic secretion	27/739	111/7206	1.91709607539e-05
ko04742	Taste transduction	18/739	61/7206	2.38531695093e-05
ko03013	RNA transport	3/739	166/7206	4.07510361818e-05
ko05203	Viral carcinogenesis	10/739	277/7206	4.50183428651e-05
ko04925	Aldosterone synthesis and secretion	25/739	105/7206	5.23483105927e-05
ko04964	Proximal tubule bicarbonate reclamation	11/739	29/7206	7.47817896551e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/739	74/7206	0.000117902342729
ko05110	Vibrio cholerae infection	17/739	63/7206	0.000138160842291
ko05164	Influenza A	4/739	167/7206	0.000146234335764
ko04070	Phosphatidylinositol signaling system	25/739	112/7206	0.000197887802549
ko04626	Plant-pathogen interaction	8/739	18/7206	0.000201940850808
ko04010	MAPK signaling pathway	54/739	321/7206	0.000214179190694
ko04072	Phospholipase D signaling pathway	37/739	197/7206	0.000286224823495
ko04514	Cell adhesion molecules (CAMs)	26/739	130/7206	0.000689273942065
ko05168	Herpes simplex infection	6/739	182/7206	0.000714966190117
ko04924	Renin secretion	19/739	86/7206	0.00100723922837
ko04745	Phototransduction - fly	11/739	38/7206	0.00109870880763
ko04621	NOD-like receptor signaling pathway	5/739	157/7206	0.00128584545172
ko04540	Gap junction	25/739	128/7206	0.00165291678978
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/739	14/7206	0.00166093816759
ko04141	Protein processing in endoplasmic reticulum	7/739	184/7206	0.00188123077668
ko04360	Axon guidance	39/739	233/7206	0.00193830751153
ko05162	Measles	3/739	120/7206	0.00209379264344
ko05169	Epstein-Barr virus infection	9/739	206/7206	0.00327822100801
ko04060	Cytokine-cytokine receptor interaction	8/739	191/7206	0.00339966644989
ko04110	Cell cycle	5/739	145/7206	0.00342225351191
ko04612	Antigen processing and presentation	1/739	77/7206	0.00397327071622
ko04976	Bile secretion	17/739	80/7206	0.00431778728856
ko04260	Cardiac muscle contraction	19/739	98/7206	0.00626145764248
ko04014	Ras signaling pathway	43/739	279/7206	0.00626415888719
ko05414	Dilated cardiomyopathy	21/739	112/7206	0.00664035473686
ko04740	Olfactory transduction	16/739	80/7206	0.00814380378266
ko04915	Estrogen signaling pathway	23/739	131/7206	0.00857350283993
ko04630	Jak-STAT signaling pathway	5/739	132/7206	0.00886486506503
ko04510	Focal adhesion	13/739	240/7206	0.00919497478663
ko04750	Inflammatory mediator regulation of TRP channels	22/739	122/7206	0.00942761076245
ko05161	Hepatitis B	8/739	173/7206	0.0106652523026
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/739	92/7206	0.0143618646921
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/739	79/7206	0.0150858992472
ko04064	NF-kappa B signaling pathway	3/739	96/7206	0.0164864424479
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/739	59/7206	0.016673353805
ko04217	Necroptosis	9/739	178/7206	0.0170994336564
ko05166	HTLV-I infection	18/739	292/7206	0.0176666931879
ko04330	Notch signaling pathway	1/739	62/7206	0.0186510780044
ko05140	Leishmaniasis	2/739	75/7206	0.021563462419
ko04930	Type II diabetes mellitus	11/739	54/7206	0.0220897573155
ko04610	Complement and coagulation cascades	2/739	79/7206	0.0226848766196
ko05205	Proteoglycans in cancer	17/739	271/7206	0.0246615176256
ko04015	Rap1 signaling pathway	40/739	278/7206	0.026031780123
ko04744	Phototransduction	8/739	36/7206	0.0265774973418
ko04214	Apoptosis - fly	2/739	72/7206	0.0305936774529
ko04960	Aldosterone-regulated sodium reabsorption	9/739	41/7206	0.0324203406273
ko04114	Oocyte meiosis	22/739	139/7206	0.0340246500609
ko04071	Sphingolipid signaling pathway	25/739	162/7206	0.0352306527637
ko04711	Circadian rhythm - fly	4/739	13/7206	0.0369193817129
ko01040	Biosynthesis of unsaturated fatty acids	6/739	25/7206	0.0369296182147
ko04710	Circadian rhythm	9/739	43/7206	0.0371719397747
ko05016	Huntington's disease	13/739	215/7206	0.0392952317511
ko00590	Arachidonic acid metabolism	1/739	52/7206	0.0393009117455
ko04011	MAPK signaling pathway - yeast	1/739	53/7206	0.039304383766
ko05215	Prostate cancer	5/739	111/7206	0.0402880804955
ko00520	Amino sugar and nucleotide sugar metabolism	1/739	55/7206	0.0405713065494
ko00650	Butanoate metabolism	6/739	26/7206	0.0439962724464
ko05202	Transcriptional misregulation in cancer	11/739	188/7206	0.0499842678904