ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 16/141 167/7206 1.32095867594e-07 ko04621 NOD-like receptor signaling pathway 14/141 157/7206 2.01610169515e-06 ko04380 Osteoclast differentiation 12/141 134/7206 1.07781275113e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/141 191/7206 1.98017868411e-05 ko04660 T cell receptor signaling pathway 11/141 124/7206 2.78600805085e-05 ko05145 Toxoplasmosis 11/141 126/7206 3.23720103941e-05 ko05152 Tuberculosis 13/141 187/7206 6.89839788942e-05 ko05162 Measles 10/141 120/7206 0.00011088557175 ko04668 TNF signaling pathway 10/141 120/7206 0.00011088557175 ko05161 Hepatitis B 12/141 173/7206 0.000135402498369 ko04620 Toll-like receptor signaling pathway 9/141 100/7206 0.000136757398997 ko04064 NF-kappa B signaling pathway 8/141 96/7206 0.000547781994057 ko04650 Natural killer cell mediated cytotoxicity 8/141 97/7206 0.000587315354449 ko05168 Herpes simplex infection 11/141 182/7206 0.000837266133175 ko04060 Cytokine-cytokine receptor interaction 11/141 191/7206 0.00124410411779 ko05215 Prostate cancer 8/141 111/7206 0.00142680914637 ko04662 B cell receptor signaling pathway 7/141 88/7206 0.00160354304348 ko04217 Necroptosis 10/141 178/7206 0.00248382518456 ko05340 Primary immunodeficiency 4/141 30/7206 0.00259235787255 ko04210 Apoptosis 10/141 180/7206 0.00269493047424 ko05160 Hepatitis C 9/141 153/7206 0.00298829762537 ko05140 Leishmaniasis 6/141 75/7206 0.00335601061848 ko04612 Antigen processing and presentation 6/141 77/7206 0.00382788515732 ko04630 Jak-STAT signaling pathway 8/141 132/7206 0.00422382238584 ko05131 Shigellosis 6/141 82/7206 0.00522174830536 ko04931 Insulin resistance 8/141 137/7206 0.00528463545575 ko04672 Intestinal immune network for IgA production 4/141 37/7206 0.00562152953246 ko05169 Epstein-Barr virus infection 10/141 206/7206 0.00698608632524 ko05166 HTLV-I infection 13/141 292/7206 0.00733724693573 ko04623 Cytosolic DNA-sensing pathway 4/141 41/7206 0.00811679948512 ko00051 Fructose and mannose metabolism 4/141 42/7206 0.00883757796105 ko05330 Allograft rejection 3/141 24/7206 0.0109862063675 ko04722 Neurotrophin signaling pathway 8/141 160/7206 0.0129789981398 ko04215 Apoptosis - multiple species 4/141 47/7206 0.0130669227834 ko05142 Chagas disease (American trypanosomiasis) 7/141 130/7206 0.0135695319192 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/141 135/7206 0.0164150164902 ko04068 FoxO signaling pathway 8/141 167/7206 0.0164475465411 ko04062 Chemokine signaling pathway 9/141 201/7206 0.0168201876913 ko04080 Neuroactive ligand-receptor interaction 2/141 423/7206 0.0172790307196 ko05320 Autoimmune thyroid disease 3/141 29/7206 0.0184771095575 ko05212 Pancreatic cancer 5/141 83/7206 0.0229422116764 ko05203 Viral carcinogenesis 11/141 277/7206 0.0233529451525 ko05321 Inflammatory bowel disease (IBD) 4/141 56/7206 0.0235289435265 ko05220 Chronic myeloid leukemia 5/141 85/7206 0.0251353182254 ko04142 Lysosome 7/141 151/7206 0.0283331440289 ko04670 Leukocyte transendothelial migration 7/141 151/7206 0.0283331440289 ko05222 Small cell lung cancer 5/141 89/7206 0.0299154431619 ko04666 Fc gamma R-mediated phagocytosis 6/141 122/7206 0.0320924552047 ko04622 RIG-I-like receptor signaling pathway 4/141 62/7206 0.0326933288062 ko04211 Longevity regulating pathway 6/141 123/7206 0.0332148019928 ko04725 Cholinergic synapse 7/141 160/7206 0.0371270485793 ko04658 Th1 and Th2 cell differentiation 5/141 96/7206 0.0395843169736 ko05132 Salmonella infection 5/141 98/7206 0.0426588178519 ko05332 Graft-versus-host disease 2/141 18/7206 0.0474022551905