ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/908	423/7206	7.60265631543e-39
ko04724	Glutamatergic synapse	77/908	152/7206	1.06601969759e-30
ko05033	Nicotine addiction	41/908	56/7206	1.44244928369e-25
ko05032	Morphine addiction	57/908	110/7206	1.34927032351e-23
ko04728	Dopaminergic synapse	76/908	185/7206	5.61460850256e-23
ko04727	GABAergic synapse	55/908	110/7206	7.86642956501e-22
ko04713	Circadian entrainment	62/908	136/7206	9.14254132165e-22
ko04725	Cholinergic synapse	64/908	160/7206	8.89177969721e-19
ko04723	Retrograde endocannabinoid signaling	67/908	175/7206	2.09325385748e-18
ko04024	cAMP signaling pathway	86/908	279/7206	2.33510528237e-16
ko04721	Synaptic vesicle cycle	40/908	80/7206	3.37837237538e-16
ko04020	Calcium signaling pathway	81/908	265/7206	3.04485667091e-15
ko04921	Oxytocin signaling pathway	69/908	209/7206	5.13317156186e-15
ko04911	Insulin secretion	48/908	117/7206	7.03240313343e-15
ko05031	Amphetamine addiction	38/908	91/7206	2.50065277582e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/908	205/7206	3.84018899651e-12
ko04726	Serotonergic synapse	47/908	137/7206	2.8853222607e-11
ko04720	Long-term potentiation	38/908	99/7206	5.30285734049e-11
ko04742	Taste transduction	28/908	61/7206	1.34759072522e-10
ko04925	Aldosterone synthesis and secretion	37/908	105/7206	1.62590411568e-09
ko04970	Salivary secretion	33/908	95/7206	1.87902600784e-08
ko04971	Gastric acid secretion	33/908	98/7206	4.48513035067e-08
ko03040	Spliceosome	1/908	145/7206	9.1187545625e-08
ko04514	Cell adhesion molecules (CAMs)	38/908	130/7206	3.22408115792e-07
ko05030	Cocaine addiction	26/908	73/7206	3.46969493729e-07
ko04010	MAPK signaling pathway	72/908	321/7206	6.65447539474e-07
ko03010	Ribosome	1/908	129/7206	7.23446802287e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/908	74/7206	1.80773572675e-06
ko05203	Viral carcinogenesis	12/908	277/7206	3.02590182026e-06
ko05168	Herpes simplex infection	5/908	182/7206	4.03385661688e-06
ko04070	Phosphatidylinositol signaling system	32/908	112/7206	4.6977869692e-06
ko05322	Systemic lupus erythematosus	3/908	151/7206	4.87382398853e-06
ko04745	Phototransduction - fly	16/908	38/7206	5.26705745063e-06
ko04022	cGMP-PKG signaling pathway	51/908	216/7206	5.57013020246e-06
ko04060	Cytokine-cytokine receptor interaction	6/908	191/7206	7.02318761508e-06
ko04740	Olfactory transduction	25/908	80/7206	8.85431325483e-06
ko04972	Pancreatic secretion	31/908	111/7206	1.53637722368e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/908	79/7206	2.26772551509e-05
ko04072	Phospholipase D signaling pathway	46/908	197/7206	2.61684906067e-05
ko04360	Axon guidance	52/908	233/7206	3.04466759569e-05
ko04744	Phototransduction	14/908	36/7206	5.95931551768e-05
ko04621	NOD-like receptor signaling pathway	5/908	157/7206	7.445025392e-05
ko04915	Estrogen signaling pathway	33/908	131/7206	8.08245361054e-05
ko05164	Influenza A	6/908	167/7206	8.1407577075e-05
ko04750	Inflammatory mediator regulation of TRP channels	31/908	122/7206	8.9279096647e-05
ko04260	Cardiac muscle contraction	26/908	98/7206	0.000161778183121
ko05110	Vibrio cholerae infection	19/908	63/7206	0.000177372752938
ko04730	Long-term depression	22/908	78/7206	0.000194023221004
ko05414	Dilated cardiomyopathy	28/908	112/7206	0.000267557304458
ko03013	RNA transport	7/908	166/7206	0.000335281493326
ko03008	Ribosome biogenesis in eukaryotes	1/908	79/7206	0.000487987318292
ko04540	Gap junction	30/908	128/7206	0.000638161994392
ko04612	Antigen processing and presentation	1/908	77/7206	0.000751608641475
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/908	14/7206	0.00075685930445
ko04966	Collecting duct acid secretion	10/908	26/7206	0.000759376383893
ko04626	Plant-pathogen interaction	8/908	18/7206	0.000840432763818
ko04924	Renin secretion	22/908	86/7206	0.000867274516009
ko04110	Cell cycle	6/908	145/7206	0.000871348733859
ko04120	Ubiquitin mediated proteolysis	6/908	138/7206	0.00166489859587
ko04114	Oocyte meiosis	30/908	139/7206	0.00269681642281
ko04064	NF-kappa B signaling pathway	3/908	96/7206	0.00274757760398
ko05162	Measles	5/908	120/7206	0.00315529362789
ko05410	Hypertrophic cardiomyopathy (HCM)	23/908	100/7206	0.00347705148388
ko04371	Apelin signaling pathway	36/908	177/7206	0.0038086843163
ko05169	Epstein-Barr virus infection	13/908	206/7206	0.00388192684965
ko05140	Leishmaniasis	2/908	75/7206	0.00465260898281
ko05161	Hepatitis B	10/908	173/7206	0.00499386724014
ko04014	Ras signaling pathway	51/908	279/7206	0.00555143235867
ko04930	Type II diabetes mellitus	14/908	54/7206	0.00646095031486
ko04922	Glucagon signaling pathway	27/908	128/7206	0.00658558975717
ko05205	Proteoglycans in cancer	20/908	271/7206	0.00663802371784
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/908	15/7206	0.0071813013866
ko04630	Jak-STAT signaling pathway	7/908	132/7206	0.00772706936255
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/908	59/7206	0.00858883047937
ko00562	Inositol phosphate metabolism	20/908	89/7206	0.00907281684525
ko04141	Protein processing in endoplasmic reticulum	12/908	184/7206	0.00936277961667
ko04916	Melanogenesis	28/908	142/7206	0.0145614758019
ko04146	Peroxisome	4/908	89/7206	0.0154449161204
ko04610	Complement and coagulation cascades	3/908	79/7206	0.0154861387504
ko04217	Necroptosis	12/908	178/7206	0.0157500385713
ko04330	Notch signaling pathway	2/908	62/7206	0.0200235219284
ko04923	Regulation of lipolysis in adipocytes	17/908	77/7206	0.022644476421
ko00512	Mucin type O-glycan biosynthesis	8/908	29/7206	0.0233588776922
ko04964	Proximal tubule bicarbonate reclamation	8/908	29/7206	0.0233588776922
ko05231	Choline metabolism in cancer	26/908	134/7206	0.0243775390793
ko03420	Nucleotide excision repair	1/908	46/7206	0.0250871554163
ko05219	Bladder cancer	1/908	48/7206	0.0259261099105
ko04912	GnRH signaling pathway	24/908	122/7206	0.0263795230245
ko04976	Bile secretion	17/908	80/7206	0.0264004232502
ko04510	Focal adhesion	19/908	240/7206	0.0288440437082
ko04214	Apoptosis - fly	3/908	72/7206	0.0301682578405
ko05010	Alzheimer's disease	36/908	202/7206	0.030729461602
ko04918	Thyroid hormone synthesis	18/908	86/7206	0.0314058525649
ko00680	Methane metabolism	9/908	34/7206	0.031818408633
ko04015	Rap1 signaling pathway	47/908	278/7206	0.0335210463143
ko00513	Various types of N-glycan biosynthesis	10/908	42/7206	0.0359011802889
ko04973	Carbohydrate digestion and absorption	10/908	42/7206	0.0359011802889
ko05016	Huntington's disease	17/908	215/7206	0.0363227887771
ko00071	Fatty acid degradation	1/908	45/7206	0.0384238521152
ko04722	Neurotrophin signaling pathway	29/908	160/7206	0.0399105157071
ko00480	Glutathione metabolism	2/908	55/7206	0.0407193346027
ko05321	Inflammatory bowel disease (IBD)	2/908	56/7206	0.0410422009229
ko03320	PPAR signaling pathway	3/908	69/7206	0.0423067300248
ko04550	Signaling pathways regulating pluripotency of stem cells	12/908	165/7206	0.0424855631384
ko05215	Prostate cancer	7/908	111/7206	0.0430633690514
ko04270	Vascular smooth muscle contraction	28/908	154/7206	0.0481963174866