ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	148/921	423/7206	3.23888360215e-34
ko05033	Nicotine addiction	40/921	56/7206	4.65517853507e-24
ko04724	Glutamatergic synapse	66/921	152/7206	2.59391126829e-21
ko04713	Circadian entrainment	52/921	136/7206	2.98255554026e-14
ko05032	Morphine addiction	45/921	110/7206	9.58755261486e-14
ko04727	GABAergic synapse	44/921	110/7206	4.68084923504e-13
ko04728	Dopaminergic synapse	58/921	185/7206	2.45870761011e-11
ko04725	Cholinergic synapse	52/921	160/7206	4.47059987234e-11
ko04024	cAMP signaling pathway	76/921	279/7206	4.56738932542e-11
ko04723	Retrograde endocannabinoid signaling	55/921	175/7206	8.24574542147e-11
ko04911	Insulin secretion	41/921	117/7206	4.00308541745e-10
ko04020	Calcium signaling pathway	71/921	265/7206	4.03679151715e-10
ko04721	Synaptic vesicle cycle	32/921	80/7206	7.51492260036e-10
ko04261	Adrenergic signaling in cardiomyocytes	59/921	205/7206	7.56432555199e-10
ko04744	Phototransduction	20/921	36/7206	1.08158906698e-09
ko04726	Serotonergic synapse	44/921	137/7206	2.19104041481e-09
ko04976	Bile secretion	31/921	80/7206	3.48687586341e-09
ko04742	Taste transduction	26/921	61/7206	6.02894290464e-09
ko04974	Protein digestion and absorption	34/921	96/7206	9.35037970109e-09
ko04921	Oxytocin signaling pathway	57/921	209/7206	1.08647371432e-08
ko04972	Pancreatic secretion	37/921	111/7206	1.37655381794e-08
ko04970	Salivary secretion	33/921	95/7206	2.67827038907e-08
ko05203	Viral carcinogenesis	10/921	277/7206	1.75729712763e-07
ko04514	Cell adhesion molecules (CAMs)	38/921	130/7206	4.5149474272e-07
ko04964	Proximal tubule bicarbonate reclamation	15/921	29/7206	4.81603732589e-07
ko04978	Mineral absorption	18/921	40/7206	5.0399675606e-07
ko04260	Cardiac muscle contraction	31/921	98/7206	7.68876895837e-07
ko03040	Spliceosome	2/921	145/7206	9.19366484395e-07
ko04120	Ubiquitin mediated proteolysis	2/921	138/7206	2.02587907102e-06
ko04060	Cytokine-cytokine receptor interaction	6/921	191/7206	4.81116950361e-06
ko05030	Cocaine addiction	24/921	73/7206	6.41750677961e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/921	74/7206	8.36767484959e-06
ko04971	Gastric acid secretion	29/921	98/7206	9.10007604347e-06
ko05168	Herpes simplex infection	6/921	182/7206	1.40846052757e-05
ko05166	HTLV-I infection	15/921	292/7206	1.45797953755e-05
ko05164	Influenza A	5/921	167/7206	1.71492930487e-05
ko05031	Amphetamine addiction	27/921	91/7206	1.86204534751e-05
ko05161	Hepatitis B	6/921	173/7206	4.10546430031e-05
ko04022	cGMP-PKG signaling pathway	49/921	216/7206	4.37863001566e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/921	79/7206	4.78784493343e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/921	182/7206	6.44054816775e-05
ko03013	RNA transport	6/921	166/7206	8.12943067931e-05
ko05205	Proteoglycans in cancer	15/921	271/7206	8.77269757068e-05
ko04924	Renin secretion	24/921	86/7206	0.000137099158443
ko05162	Measles	3/921	120/7206	0.000144713019642
ko04730	Long-term depression	22/921	78/7206	0.000229137214556
ko04621	NOD-like receptor signaling pathway	6/921	157/7206	0.000231452354177
ko04550	Signaling pathways regulating pluripotency of stem cells	7/921	165/7206	0.000336719605479
ko05410	Hypertrophic cardiomyopathy (HCM)	26/921	100/7206	0.000375091472522
ko04141	Protein processing in endoplasmic reticulum	9/921	184/7206	0.000469815344246
ko03008	Ribosome biogenesis in eukaryotes	1/921	79/7206	0.000496141894743
ko04740	Olfactory transduction	22/921	80/7206	0.000522054717425
ko05169	Epstein-Barr virus infection	11/921	206/7206	0.000621012856319
ko04720	Long-term potentiation	25/921	99/7206	0.000663463624597
ko04630	Jak-STAT signaling pathway	5/921	132/7206	0.000834571279117
ko05414	Dilated cardiomyopathy	27/921	112/7206	0.000868752106082
ko05322	Systemic lupus erythematosus	7/921	151/7206	0.00121094359641
ko05215	Prostate cancer	4/921	111/7206	0.00145787187418
ko05220	Chronic myeloid leukemia	2/921	85/7206	0.00153522105781
ko04150	mTOR signaling pathway	10/921	184/7206	0.00156486463371
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/921	135/7206	0.00163435665918
ko05016	Huntington's disease	13/921	215/7206	0.00172101292549
ko04512	ECM-receptor interaction	20/921	79/7206	0.00199764272589
ko04110	Cell cycle	7/921	145/7206	0.00229562831293
ko05200	Pathways in cancer	42/921	492/7206	0.00260000033169
ko04142	Lysosome	8/921	151/7206	0.00300733797352
ko04010	MAPK signaling pathway	59/921	321/7206	0.00348886733718
ko04330	Notch signaling pathway	1/921	62/7206	0.00353372069442
ko04925	Aldosterone synthesis and secretion	24/921	105/7206	0.00448983720242
ko04210	Apoptosis	11/921	180/7206	0.00451517953039
ko04218	Cellular senescence	11/921	177/7206	0.00594982376517
ko04214	Apoptosis - fly	2/921	72/7206	0.00679145645613
ko04540	Gap junction	27/921	128/7206	0.00718633183495
ko00290	Valine, leucine and isoleucine biosynthesis	3/921	4/7206	0.00753162497367
ko04137	Mitophagy - animal	3/921	82/7206	0.0075539992332
ko01521	EGFR tyrosine kinase inhibitor resistance	5/921	106/7206	0.0080631375678
ko04064	NF-kappa B signaling pathway	4/921	96/7206	0.00807731706382
ko04668	TNF signaling pathway	6/921	120/7206	0.00809797032729
ko00830	Retinol metabolism	12/921	42/7206	0.00815171808155
ko04140	Autophagy - animal	10/921	164/7206	0.00868003015361
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/921	59/7206	0.00900969313109
ko00190	Oxidative phosphorylation	7/921	127/7206	0.0103386924275
ko04350	TGF-beta signaling pathway	5/921	103/7206	0.0110686891671
ko04011	MAPK signaling pathway - yeast	1/921	53/7206	0.011605677908
ko04217	Necroptosis	12/921	178/7206	0.012061400839
ko05206	MicroRNAs in cancer	12/921	177/7206	0.0120630023621
ko04066	HIF-1 signaling pathway	7/921	123/7206	0.0138311813998
ko00564	Glycerophospholipid metabolism	5/921	99/7206	0.0151580740424
ko05224	Breast cancer	12/921	174/7206	0.0155662555628
ko00240	Pyrimidine metabolism	6/921	110/7206	0.0200754331099
ko04614	Renin-angiotensin system	6/921	18/7206	0.0204188849908
ko05211	Renal cell carcinoma	5/921	96/7206	0.0206306429052
ko00310	Lysine degradation	3/921	73/7206	0.0211081286465
ko04657	IL-17 signaling pathway	4/921	87/7206	0.0219696761981
ko00250	Alanine, aspartate and glutamate metabolism	10/921	38/7206	0.0236349802228
ko03420	Nucleotide excision repair	1/921	46/7206	0.0250227573154
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/921	14/7206	0.0250382148843
ko05202	Transcriptional misregulation in cancer	14/921	188/7206	0.0262234938226
ko04931	Insulin resistance	9/921	137/7206	0.0272357740749
ko04660	T cell receptor signaling pathway	8/921	124/7206	0.0297725090833
ko04146	Peroxisome	5/921	89/7206	0.037822490401
ko05321	Inflammatory bowel disease (IBD)	2/921	56/7206	0.04147929809
ko05217	Basal cell carcinoma	3/921	68/7206	0.0420834751262
ko05152	Tuberculosis	15/921	187/7206	0.0459832112416
ko04650	Natural killer cell mediated cytotoxicity	6/921	97/7206	0.046911175183
ko04620	Toll-like receptor signaling pathway	6/921	100/7206	0.0479405895425
ko00230	Purine metabolism	34/921	194/7206	0.0495793735248