ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	69/620	152/7206	2.23362059792e-34
ko04080	Neuroactive ligand-receptor interaction	109/620	423/7206	1.01864083264e-27
ko05033	Nicotine addiction	36/620	56/7206	2.59846259975e-25
ko04728	Dopaminergic synapse	59/620	185/7206	4.81722813182e-20
ko04723	Retrograde endocannabinoid signaling	56/620	175/7206	3.8004956036e-19
ko04727	GABAergic synapse	43/620	110/7206	1.15818760623e-18
ko04713	Circadian entrainment	48/620	136/7206	1.56518749683e-18
ko05032	Morphine addiction	41/620	110/7206	5.73308616547e-17
ko04024	cAMP signaling pathway	68/620	279/7206	5.19877170106e-16
ko04911	Insulin secretion	38/620	117/7206	1.4155909698e-13
ko04726	Serotonergic synapse	40/620	137/7206	1.59732742382e-12
ko04720	Long-term potentiation	33/620	99/7206	2.62742813912e-12
ko04020	Calcium signaling pathway	58/620	265/7206	1.11904905326e-11
ko05031	Amphetamine addiction	30/620	91/7206	3.63550194828e-11
ko04261	Adrenergic signaling in cardiomyocytes	48/620	205/7206	6.21236346594e-11
ko04725	Cholinergic synapse	41/620	160/7206	8.32647555171e-11
ko04742	Taste transduction	23/620	61/7206	3.46278798251e-10
ko04721	Synaptic vesicle cycle	26/620	80/7206	1.07084809531e-09
ko04921	Oxytocin signaling pathway	46/620	209/7206	1.40375273764e-09
ko05030	Cocaine addiction	23/620	73/7206	1.94072978954e-08
ko04010	MAPK signaling pathway	57/620	321/7206	1.09170067002e-07
ko04072	Phospholipase D signaling pathway	38/620	197/7206	1.72671582076e-06
ko04925	Aldosterone synthesis and secretion	25/620	105/7206	1.90143684377e-06
ko05203	Viral carcinogenesis	5/620	277/7206	2.86398266903e-06
ko04970	Salivary secretion	23/620	95/7206	3.61059953563e-06
ko04514	Cell adhesion molecules (CAMs)	28/620	130/7206	3.90988493914e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	19/620	74/7206	1.02054612931e-05
ko04022	cGMP-PKG signaling pathway	38/620	216/7206	1.84921526765e-05
ko03040	Spliceosome	1/620	145/7206	6.21426847237e-05
ko04260	Cardiac muscle contraction	21/620	98/7206	6.81104906422e-05
ko04730	Long-term depression	18/620	78/7206	8.11197497473e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/620	79/7206	9.68122155315e-05
ko04070	Phosphatidylinositol signaling system	23/620	112/7206	0.000101710872584
ko05168	Herpes simplex infection	3/620	182/7206	0.000132845800604
ko04972	Pancreatic secretion	22/620	111/7206	0.00019921093371
ko04014	Ras signaling pathway	41/620	279/7206	0.000643628492927
ko04744	Phototransduction	10/620	36/7206	0.000668656527345
ko04915	Estrogen signaling pathway	23/620	131/7206	0.000797886190264
ko00240	Pyrimidine metabolism	1/620	110/7206	0.000913296874563
ko04745	Phototransduction - fly	10/620	38/7206	0.00106251973345
ko05010	Alzheimer's disease	31/620	202/7206	0.00131150496118
ko04971	Gastric acid secretion	18/620	98/7206	0.00167809644692
ko05414	Dilated cardiomyopathy	20/620	112/7206	0.00169607938072
ko04740	Olfactory transduction	15/620	80/7206	0.00372062537579
ko00562	Inositol phosphate metabolism	16/620	89/7206	0.00376264161321
ko05205	Proteoglycans in cancer	11/620	271/7206	0.0040017803429
ko04360	Axon guidance	33/620	233/7206	0.00404284915651
ko04750	Inflammatory mediator regulation of TRP channels	20/620	122/7206	0.00480652527187
ko05322	Systemic lupus erythematosus	4/620	151/7206	0.00486661571249
ko05164	Influenza A	5/620	167/7206	0.00501718119826
ko05410	Hypertrophic cardiomyopathy (HCM)	17/620	100/7206	0.00597940259008
ko04110	Cell cycle	4/620	145/7206	0.00671544322872
ko04550	Signaling pathways regulating pluripotency of stem cells	5/620	165/7206	0.00696772341116
ko04621	NOD-like receptor signaling pathway	5/620	157/7206	0.00936917442285
ko05034	Alcoholism	32/620	238/7206	0.00954156820848
ko04540	Gap junction	20/620	128/7206	0.00967209669791
ko00512	Mucin type O-glycan biosynthesis	7/620	29/7206	0.00984728455567
ko04924	Renin secretion	15/620	86/7206	0.0099193552949
ko05169	Epstein-Barr virus infection	8/620	206/7206	0.0111912693385
ko04610	Complement and coagulation cascades	1/620	79/7206	0.0135705311728
ko03008	Ribosome biogenesis in eukaryotes	1/620	79/7206	0.0135705311728
ko04141	Protein processing in endoplasmic reticulum	7/620	184/7206	0.0157961549048
ko03013	RNA transport	6/620	166/7206	0.0166258808939
ko04630	Jak-STAT signaling pathway	4/620	132/7206	0.0176549554805
ko05140	Leishmaniasis	1/620	75/7206	0.0200559861671
ko04930	Type II diabetes mellitus	10/620	54/7206	0.0230630377328
ko00513	Various types of N-glycan biosynthesis	8/620	42/7206	0.0246795950907
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/620	14/7206	0.0270375173423
ko05231	Choline metabolism in cancer	19/620	134/7206	0.0280992093824
ko04371	Apelin signaling pathway	24/620	177/7206	0.0284265857539
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	6/620	28/7206	0.0290259644103
ko04722	Neurotrophin signaling pathway	22/620	160/7206	0.0307635638287
ko05162	Measles	4/620	120/7206	0.0325715653238
ko04150	mTOR signaling pathway	8/620	184/7206	0.0329919700989
ko04146	Peroxisome	2/620	89/7206	0.0333020503852
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/620	15/7206	0.0344265260484
ko00510	N-Glycan biosynthesis	9/620	50/7206	0.0359713835323
ko04012	ErbB signaling pathway	16/620	109/7206	0.0361431679297
ko04330	Notch signaling pathway	1/620	62/7206	0.0409357583719
ko04640	Hematopoietic cell lineage	1/620	64/7206	0.0412204033109
ko04912	GnRH signaling pathway	17/620	122/7206	0.0481379619672