ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 19/339 79/7206 2.42401030254e-09 ko04974 Protein digestion and absorption 19/339 96/7206 7.38525205606e-08 ko04514 Cell adhesion molecules (CAMs) 21/339 130/7206 5.71618111601e-07 ko04721 Synaptic vesicle cycle 16/339 80/7206 6.96063921148e-07 ko04151 PI3K-Akt signaling pathway 37/339 390/7206 3.60392207559e-05 ko04727 GABAergic synapse 16/339 110/7206 4.96152678352e-05 ko04724 Glutamatergic synapse 18/339 152/7206 0.000259765700473 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/339 79/7206 0.000286933361924 ko04964 Proximal tubule bicarbonate reclamation 7/339 29/7206 0.000304770744505 ko04911 Insulin secretion 15/339 117/7206 0.000356962307822 ko04360 Axon guidance 24/339 233/7206 0.00037351360652 ko04510 Focal adhesion 24/339 240/7206 0.00046416691478 ko04728 Dopaminergic synapse 20/339 185/7206 0.000528352343926 ko05033 Nicotine addiction 9/339 56/7206 0.00108313480508 ko04725 Cholinergic synapse 17/339 160/7206 0.00174153288098 ko04261 Adrenergic signaling in cardiomyocytes 20/339 205/7206 0.00200643616433 ko04910 Insulin signaling pathway 1/339 172/7206 0.00510741158299 ko05203 Viral carcinogenesis 4/339 277/7206 0.00541431791325 ko04611 Platelet activation 1/339 163/7206 0.00735794970591 ko04060 Cytokine-cytokine receptor interaction 2/339 191/7206 0.00879545792749 ko04723 Retrograde endocannabinoid signaling 16/339 175/7206 0.0100002782354 ko05322 Systemic lupus erythematosus 1/339 151/7206 0.0103058790282 ko03015 mRNA surveillance pathway 10/339 93/7206 0.0116568666826 ko04976 Bile secretion 9/339 80/7206 0.0123625592325 ko05168 Herpes simplex infection 2/339 182/7206 0.0124496220866 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/339 182/7206 0.0124496220866 ko00350 Tyrosine metabolism 5/339 33/7206 0.0179336798909 ko04961 Endocrine and other factor-regulated calcium reabsorption 7/339 59/7206 0.0199513247065 ko04915 Estrogen signaling pathway 1/339 131/7206 0.0214198925597 ko04010 MAPK signaling pathway 24/339 321/7206 0.02144515926 ko05014 Amyotrophic lateral sclerosis (ALS) 8/339 74/7206 0.0222576270614 ko04080 Neuroactive ligand-receptor interaction 30/339 423/7206 0.0236389050121 ko04140 Autophagy - animal 2/339 164/7206 0.0247287943047 ko03013 RNA transport 2/339 166/7206 0.0247756916053 ko05164 Influenza A 2/339 167/7206 0.0248639024235 ko04260 Cardiac muscle contraction 10/339 98/7206 0.0250583631968 ko05410 Hypertrophic cardiomyopathy (HCM) 10/339 100/7206 0.026536064024 ko05012 Parkinson's disease 2/339 155/7206 0.034683043535 ko04391 Hippo signaling pathway - fly 9/339 90/7206 0.0377852111222 ko05032 Morphine addiction 10/339 110/7206 0.038494781569 ko05414 Dilated cardiomyopathy 10/339 112/7206 0.0418334961293 ko04916 Melanogenesis 12/339 142/7206 0.0430076900111 ko04970 Salivary secretion 9/339 95/7206 0.0440227202133 ko00830 Retinol metabolism 5/339 42/7206 0.0457083203522 ko04668 TNF signaling pathway 1/339 120/7206 0.045892281114 ko05016 Huntington's disease 4/339 215/7206 0.0476477051865