ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	161/950	423/7206	6.61719099602e-41
ko04724	Glutamatergic synapse	72/950	152/7206	3.60356072104e-25
ko05033	Nicotine addiction	40/950	56/7206	1.53750226329e-23
ko05032	Morphine addiction	57/950	110/7206	1.35968596073e-22
ko04713	Circadian entrainment	59/950	136/7206	1.80215942411e-18
ko04727	GABAergic synapse	52/950	110/7206	2.03507206556e-18
ko04721	Synaptic vesicle cycle	43/950	80/7206	4.04128721438e-18
ko04728	Dopaminergic synapse	69/950	185/7206	3.95899661755e-17
ko04723	Retrograde endocannabinoid signaling	66/950	175/7206	1.02340180817e-16
ko04725	Cholinergic synapse	60/950	160/7206	3.64674068591e-15
ko04020	Calcium signaling pathway	80/950	265/7206	1.4386528734e-13
ko04911	Insulin secretion	47/950	117/7206	1.97057482613e-13
ko04921	Oxytocin signaling pathway	68/950	209/7206	2.70024489053e-13
ko04726	Serotonergic synapse	50/950	137/7206	2.57050857647e-12
ko04024	cAMP signaling pathway	80/950	279/7206	3.04259788197e-12
ko04742	Taste transduction	29/950	61/7206	6.56456220772e-11
ko04261	Adrenergic signaling in cardiomyocytes	59/950	205/7206	2.81213797332e-09
ko05031	Amphetamine addiction	34/950	91/7206	4.2581200696e-09
ko04970	Salivary secretion	33/950	95/7206	5.75890391229e-08
ko04060	Cytokine-cytokine receptor interaction	4/950	191/7206	9.5333787694e-08
ko04022	cGMP-PKG signaling pathway	57/950	216/7206	1.16455803369e-07
ko04720	Long-term potentiation	32/950	99/7206	5.99483335854e-07
ko03040	Spliceosome	2/950	145/7206	6.16285254393e-07
ko04925	Aldosterone synthesis and secretion	33/950	105/7206	1.14436159689e-06
ko05168	Herpes simplex infection	5/950	182/7206	1.90770269558e-06
ko05322	Systemic lupus erythematosus	3/950	151/7206	2.14386545388e-06
ko05030	Cocaine addiction	25/950	73/7206	3.14643494534e-06
ko04971	Gastric acid secretion	30/950	98/7206	5.62518695052e-06
ko04966	Collecting duct acid secretion	13/950	26/7206	6.62725132935e-06
ko05164	Influenza A	5/950	167/7206	7.87596183541e-06
ko04120	Ubiquitin mediated proteolysis	3/950	138/7206	9.83781359881e-06
ko04730	Long-term depression	25/950	78/7206	1.20107909482e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	24/950	74/7206	1.42933874913e-05
ko04260	Cardiac muscle contraction	29/950	98/7206	1.50822324911e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/950	79/7206	1.54121668689e-05
ko05203	Viral carcinogenesis	15/950	277/7206	2.60116380622e-05
ko04360	Axon guidance	54/950	233/7206	2.81147007739e-05
ko04972	Pancreatic secretion	31/950	111/7206	2.8518532019e-05
ko05110	Vibrio cholerae infection	21/950	63/7206	3.06383607525e-05
ko04371	Apelin signaling pathway	43/950	177/7206	4.27919938004e-05
ko04010	MAPK signaling pathway	68/950	321/7206	4.52431967969e-05
ko04514	Cell adhesion molecules (CAMs)	34/950	130/7206	6.16189575348e-05
ko04740	Olfactory transduction	24/950	80/7206	7.17921752626e-05
ko04540	Gap junction	33/950	128/7206	0.000101256971789
ko05414	Dilated cardiomyopathy	30/950	112/7206	0.000101727608225
ko04621	NOD-like receptor signaling pathway	6/950	157/7206	0.000110030139814
ko03013	RNA transport	7/950	166/7206	0.000167826059481
ko05410	Hypertrophic cardiomyopathy (HCM)	27/950	100/7206	0.000246926814807
ko04610	Complement and coagulation cascades	1/950	79/7206	0.000315737082158
ko03008	Ribosome biogenesis in eukaryotes	1/950	79/7206	0.000315737082158
ko05162	Measles	4/950	120/7206	0.000348961171994
ko04630	Jak-STAT signaling pathway	5/950	132/7206	0.00039452300977
ko04270	Vascular smooth muscle contraction	36/950	154/7206	0.000427450036067
ko04924	Renin secretion	23/950	86/7206	0.000623250903117
ko04745	Phototransduction - fly	13/950	38/7206	0.000750233465405
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/950	59/7206	0.00139165745311
ko04930	Type II diabetes mellitus	16/950	54/7206	0.00162749265946
ko04141	Protein processing in endoplasmic reticulum	11/950	184/7206	0.00190689082751
ko04750	Inflammatory mediator regulation of TRP channels	28/950	122/7206	0.00269704855268
ko04146	Peroxisome	3/950	89/7206	0.00386045066516
ko04110	Cell cycle	8/950	145/7206	0.00401033404778
ko05169	Epstein-Barr virus infection	14/950	206/7206	0.004542545855
ko00310	Lysine degradation	2/950	73/7206	0.00461355304458
ko05166	HTLV-I infection	23/950	292/7206	0.00463233876961
ko04922	Glucagon signaling pathway	28/950	128/7206	0.00542511488315
ko04626	Plant-pathogen interaction	7/950	18/7206	0.00574734847973
ko04070	Phosphatidylinositol signaling system	25/950	112/7206	0.0069310163054
ko00280	Valine, leucine and isoleucine degradation	1/950	54/7206	0.00764510133441
ko00520	Amino sugar and nucleotide sugar metabolism	1/950	55/7206	0.00782686125295
ko04916	Melanogenesis	30/950	142/7206	0.00797737050113
ko04915	Estrogen signaling pathway	28/950	131/7206	0.00857210368135
ko04964	Proximal tubule bicarbonate reclamation	9/950	29/7206	0.00987568251713
ko05205	Proteoglycans in cancer	22/950	271/7206	0.0102051737387
ko04612	Antigen processing and presentation	3/950	77/7206	0.0104945326666
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/950	92/7206	0.0118351410015
ko05161	Hepatitis B	12/950	173/7206	0.0119195830052
ko04330	Notch signaling pathway	2/950	62/7206	0.013655789486
ko00561	Glycerolipid metabolism	2/950	63/7206	0.0137519042148
ko04014	Ras signaling pathway	51/950	279/7206	0.0144304473263
ko00240	Pyrimidine metabolism	6/950	110/7206	0.0147194737433
ko04064	NF-kappa B signaling pathway	5/950	96/7206	0.0149482480166
ko05140	Leishmaniasis	3/950	75/7206	0.0149965920754
ko01524	Platinum drug resistance	3/950	76/7206	0.0153820020554
ko05204	Chemical carcinogenesis	1/950	48/7206	0.0168030708813
ko04217	Necroptosis	13/950	178/7206	0.0179028983786
ko05016	Huntington's disease	17/950	215/7206	0.018294191476
ko00330	Arginine and proline metabolism	2/950	61/7206	0.0203172960202
ko04214	Apoptosis - fly	3/950	72/7206	0.0211662449493
ko00010	Glycolysis / Gluconeogenesis	17/950	74/7206	0.0226036148135
ko03420	Nucleotide excision repair	1/950	46/7206	0.0255637157998
ko05321	Inflammatory bowel disease (IBD)	2/950	56/7206	0.0281137381785
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/950	14/7206	0.0283042408497
ko00140	Steroid hormone biosynthesis	1/950	41/7206	0.0362832749418
ko04657	IL-17 signaling pathway	5/950	87/7206	0.0374406348643
ko00590	Arachidonic acid metabolism	2/950	52/7206	0.040150172227
ko04640	Hematopoietic cell lineage	3/950	64/7206	0.0406631127423
ko04976	Bile secretion	17/950	80/7206	0.043982586383
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/950	182/7206	0.0455496315067
ko04071	Sphingolipid signaling pathway	30/950	162/7206	0.0460406840925
ko04962	Vasopressin-regulated water reabsorption	13/950	58/7206	0.0488101844637