ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	201/1208	423/7206	1.67727950489e-52
ko05033	Nicotine addiction	49/1208	56/7206	2.9965119731e-31
ko04724	Glutamatergic synapse	88/1208	152/7206	3.91881016881e-31
ko05032	Morphine addiction	68/1208	110/7206	1.22667982699e-26
ko04727	GABAergic synapse	65/1208	110/7206	6.24356702193e-24
ko04713	Circadian entrainment	73/1208	136/7206	3.17636515628e-23
ko04728	Dopaminergic synapse	86/1208	185/7206	1.28314077127e-21
ko04721	Synaptic vesicle cycle	50/1208	80/7206	3.47775952477e-20
ko04725	Cholinergic synapse	75/1208	160/7206	3.02863322562e-19
ko04024	cAMP signaling pathway	106/1208	279/7206	4.02175713329e-18
ko04723	Retrograde endocannabinoid signaling	77/1208	175/7206	1.0110290175e-17
ko04020	Calcium signaling pathway	99/1208	265/7206	2.94804316036e-16
ko04742	Taste transduction	36/1208	61/7206	8.92803192958e-14
ko04921	Oxytocin signaling pathway	77/1208	209/7206	1.2611662428e-12
ko04744	Phototransduction	25/1208	36/7206	2.98131648874e-12
ko04261	Adrenergic signaling in cardiomyocytes	75/1208	205/7206	3.59502572811e-12
ko04911	Insulin secretion	51/1208	117/7206	5.864482871e-12
ko04360	Axon guidance	80/1208	233/7206	4.32064527988e-11
ko04726	Serotonergic synapse	55/1208	137/7206	5.40368417556e-11
ko03040	Spliceosome	1/1208	145/7206	1.17599884518e-10
ko05031	Amphetamine addiction	41/1208	91/7206	2.05555488279e-10
ko04720	Long-term potentiation	43/1208	99/7206	3.15222339287e-10
ko04970	Salivary secretion	40/1208	95/7206	3.98475564009e-09
ko05203	Viral carcinogenesis	15/1208	277/7206	9.5262943347e-09
ko05168	Herpes simplex infection	8/1208	182/7206	3.3419427278e-07
ko04022	cGMP-PKG signaling pathway	66/1208	216/7206	3.84544372651e-07
ko05322	Systemic lupus erythematosus	5/1208	151/7206	3.87613020235e-07
ko04060	Cytokine-cytokine receptor interaction	9/1208	191/7206	5.7495158935e-07
ko05030	Cocaine addiction	30/1208	73/7206	6.63649637034e-07
ko03013	RNA transport	7/1208	166/7206	8.51501970307e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	30/1208	74/7206	9.39770024958e-07
ko04925	Aldosterone synthesis and secretion	38/1208	105/7206	1.15591474657e-06
ko04740	Olfactory transduction	31/1208	80/7206	2.36491279772e-06
ko05164	Influenza A	8/1208	167/7206	2.91467709057e-06
ko04971	Gastric acid secretion	35/1208	98/7206	4.31258150981e-06
ko04010	MAPK signaling pathway	85/1208	321/7206	7.78438034909e-06
ko04141	Protein processing in endoplasmic reticulum	11/1208	184/7206	1.40254089297e-05
ko04070	Phosphatidylinositol signaling system	37/1208	112/7206	1.91727663976e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1208	79/7206	5.08522234656e-05
ko04924	Renin secretion	30/1208	86/7206	5.44051644065e-05
ko05169	Epstein-Barr virus infection	15/1208	206/7206	8.88764204004e-05
ko04966	Collecting duct acid secretion	13/1208	26/7206	9.33193986463e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1208	79/7206	0.000110379235287
ko04621	NOD-like receptor signaling pathway	10/1208	157/7206	0.000136640121894
ko05205	Proteoglycans in cancer	24/1208	271/7206	0.000178611839005
ko04745	Phototransduction - fly	16/1208	38/7206	0.0001955804876
ko05140	Leishmaniasis	2/1208	75/7206	0.000250303422299
ko04972	Pancreatic secretion	34/1208	111/7206	0.000270169070268
ko04540	Gap junction	38/1208	128/7206	0.000277033918366
ko05414	Dilated cardiomyopathy	34/1208	112/7206	0.000302573816546
ko04730	Long-term depression	26/1208	78/7206	0.000330985436595
ko04120	Ubiquitin mediated proteolysis	9/1208	138/7206	0.000495817667656
ko04014	Ras signaling pathway	69/1208	279/7206	0.000556560462937
ko04260	Cardiac muscle contraction	30/1208	98/7206	0.000575317895038
ko04072	Phospholipase D signaling pathway	52/1208	197/7206	0.000641869883896
ko04110	Cell cycle	10/1208	145/7206	0.000668084168137
ko00240	Pyrimidine metabolism	6/1208	110/7206	0.000685946496943
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1208	14/7206	0.000705688610028
ko04514	Cell adhesion molecules (CAMs)	37/1208	130/7206	0.000789156329143
ko04146	Peroxisome	4/1208	89/7206	0.000828572292127
ko00480	Glutathione metabolism	1/1208	55/7206	0.000836836875662
ko04915	Estrogen signaling pathway	37/1208	131/7206	0.000852999845137
ko04612	Antigen processing and presentation	3/1208	77/7206	0.00102679994967
ko05110	Vibrio cholerae infection	21/1208	63/7206	0.00108932583069
ko04640	Hematopoietic cell lineage	2/1208	64/7206	0.00118677589023
ko00590	Arachidonic acid metabolism	1/1208	52/7206	0.00125966945622
ko04064	NF-kappa B signaling pathway	5/1208	96/7206	0.00130667079826
ko00330	Arginine and proline metabolism	2/1208	61/7206	0.00176085459718
ko04923	Regulation of lipolysis in adipocytes	24/1208	77/7206	0.00177981802345
ko05161	Hepatitis B	15/1208	173/7206	0.00268057599954
ko00260	Glycine, serine and threonine metabolism	1/1208	48/7206	0.00291085979099
ko04976	Bile secretion	24/1208	80/7206	0.00364540954313
ko05321	Inflammatory bowel disease (IBD)	2/1208	56/7206	0.00381392100168
ko05162	Measles	9/1208	120/7206	0.00431415368694
ko05144	Malaria	1/1208	45/7206	0.00432948338251
ko00071	Fatty acid degradation	1/1208	45/7206	0.00432948338251
ko03420	Nucleotide excision repair	1/1208	46/7206	0.00447158380103
ko03018	RNA degradation	5/1208	84/7206	0.00487866857032
ko04964	Proximal tubule bicarbonate reclamation	11/1208	29/7206	0.00516123305349
ko04626	Plant-pathogen interaction	8/1208	18/7206	0.00547787646202
ko04371	Apelin signaling pathway	44/1208	177/7206	0.00565950010844
ko04214	Apoptosis - fly	4/1208	72/7206	0.00670501326658
ko00310	Lysine degradation	4/1208	73/7206	0.00675107092717
ko03022	Basal transcription factors	1/1208	44/7206	0.00690860323486
ko04750	Inflammatory mediator regulation of TRP channels	32/1208	122/7206	0.0069486476547
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1208	59/7206	0.00791605192791
ko04657	IL-17 signaling pathway	6/1208	87/7206	0.00922831967408
ko05133	Pertussis	6/1208	87/7206	0.00922831967408
ko04622	RIG-I-like receptor signaling pathway	3/1208	62/7206	0.00928786039781
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1208	100/7206	0.00971820087476
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1208	40/7206	0.00977067208741
ko04015	Rap1 signaling pathway	63/1208	278/7206	0.0108649949596
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1208	182/7206	0.0115659481317
ko00380	Tryptophan metabolism	2/1208	50/7206	0.0120767824023
ko00562	Inositol phosphate metabolism	24/1208	89/7206	0.0143905077919
ko00982	Drug metabolism - cytochrome P450	1/1208	37/7206	0.0146398614266
ko00630	Glyoxylate and dicarboxylate metabolism	1/1208	38/7206	0.0147758287821
ko05131	Shigellosis	6/1208	82/7206	0.0171763202793
ko04115	p53 signaling pathway	5/1208	74/7206	0.0180837520751
ko04670	Leukocyte transendothelial migration	15/1208	151/7206	0.0206533028136
ko04140	Autophagy - animal	17/1208	164/7206	0.0259660227568
ko04658	Th1 and Th2 cell differentiation	8/1208	96/7206	0.0266999480197
ko05145	Toxoplasmosis	12/1208	126/7206	0.0295115527105
ko04722	Neurotrophin signaling pathway	37/1208	160/7206	0.0324836664196
ko03320	PPAR signaling pathway	5/1208	69/7206	0.0339863313478
ko04916	Melanogenesis	33/1208	142/7206	0.0411169264917
ko04620	Toll-like receptor signaling pathway	9/1208	100/7206	0.0418156147908
ko04930	Type II diabetes mellitus	15/1208	54/7206	0.0418963963096
ko01200	Carbon metabolism	13/1208	128/7206	0.0423490565157
ko04136	Autophagy - other	1/1208	31/7206	0.0498338747937