ko pathway ratio_in_study ratio_in_pop p_value ko04137 Mitophagy - animal 21/628 82/7206 4.49549907492e-06 ko04710 Circadian rhythm 14/628 43/7206 9.09350030209e-06 ko04070 Phosphatidylinositol signaling system 24/628 112/7206 2.58809256928e-05 ko03040 Spliceosome 1/628 145/7206 3.95366806044e-05 ko04136 Autophagy - other 10/628 31/7206 0.000192553229298 ko03010 Ribosome 1/628 129/7206 0.000197417536173 ko04966 Collecting duct acid secretion 9/628 26/7206 0.000220482087176 ko04138 Autophagy - yeast 17/628 81/7206 0.000496595750929 ko00051 Fructose and mannose metabolism 11/628 42/7206 0.000702472902115 ko05321 Inflammatory bowel disease (IBD) 13/628 56/7206 0.000829007422224 ko05323 Rheumatoid arthritis 18/628 89/7206 0.000833833437007 ko01040 Biosynthesis of unsaturated fatty acids 8/628 25/7206 0.000901928571158 ko04145 Phagosome 27/628 162/7206 0.000974477670601 ko04060 Cytokine-cytokine receptor interaction 30/628 191/7206 0.00154510322092 ko04110 Cell cycle 3/628 145/7206 0.00157773204488 ko04921 Oxytocin signaling pathway 32/628 209/7206 0.00162650616632 ko04650 Natural killer cell mediated cytotoxicity 18/628 97/7206 0.00171147659243 ko04020 Calcium signaling pathway 38/628 265/7206 0.00180403801851 ko04922 Glucagon signaling pathway 22/628 128/7206 0.00213780453431 ko04068 FoxO signaling pathway 26/628 167/7206 0.0032084802624 ko04371 Apelin signaling pathway 27/628 177/7206 0.00409713199801 ko04146 Peroxisome 16/628 89/7206 0.00419645612894 ko04745 Phototransduction - fly 9/628 38/7206 0.00446015488371 ko04022 cGMP-PKG signaling pathway 31/628 216/7206 0.00470721738519 ko05322 Systemic lupus erythematosus 4/628 151/7206 0.00496082062186 ko03013 RNA transport 5/628 166/7206 0.00500189649322 ko00120 Primary bile acid biosynthesis 6/628 20/7206 0.00572708576041 ko04630 Jak-STAT signaling pathway 21/628 132/7206 0.0071017331874 ko00680 Methane metabolism 8/628 34/7206 0.00751771454188 ko04380 Osteoclast differentiation 21/628 134/7206 0.00771869705923 ko04610 Complement and coagulation cascades 14/628 79/7206 0.00838169770391 ko05224 Breast cancer 6/628 174/7206 0.00919925720261 ko00190 Oxidative phosphorylation 20/628 127/7206 0.00983993818158 ko05110 Vibrio cholerae infection 12/628 63/7206 0.0104825433372 ko04611 Platelet activation 24/628 163/7206 0.0105726685972 ko00010 Glycolysis / Gluconeogenesis 13/628 74/7206 0.0118796286016 ko04390 Hippo signaling pathway 7/628 188/7206 0.0119947363749 ko00562 Inositol phosphate metabolism 15/628 89/7206 0.0121350556421 ko05203 Viral carcinogenesis 13/628 277/7206 0.0122887402716 ko05167 Kaposi's sarcoma-associated herpesvirus infection 27/628 191/7206 0.0126005431288 ko03008 Ribosome biogenesis in eukaryotes 1/628 79/7206 0.0138314795433 ko04621 NOD-like receptor signaling pathway 23/628 157/7206 0.0138549958408 ko00071 Fatty acid degradation 9/628 45/7206 0.0140353538046 ko04626 Plant-pathogen interaction 5/628 18/7206 0.0162664836469 ko04550 Signaling pathways regulating pluripotency of stem cells 6/628 165/7206 0.0166889493298 ko05152 Tuberculosis 26/628 187/7206 0.0170578363206 ko05034 Alcoholism 11/628 238/7206 0.0191921712803 ko04713 Circadian entrainment 20/628 136/7206 0.0198566688027 ko00592 alpha-Linolenic acid metabolism 5/628 19/7206 0.0205324106249 ko04726 Serotonergic synapse 20/628 137/7206 0.0205449539864 ko04925 Aldosterone synthesis and secretion 16/628 105/7206 0.0229648586414 ko00140 Steroid hormone biosynthesis 8/628 41/7206 0.023091885256 ko04730 Long-term depression 13/628 78/7206 0.0231244234472 ko04640 Hematopoietic cell lineage 11/628 64/7206 0.0240301362082 ko04072 Phospholipase D signaling pathway 26/628 197/7206 0.0290425452039 ko00564 Glycerophospholipid metabolism 15/628 99/7206 0.0300130789291 ko00750 Vitamin B6 metabolism 3/628 9/7206 0.0371475937976 ko01212 Fatty acid metabolism 10/628 60/7206 0.0372023622536 ko04672 Intestinal immune network for IgA production 7/628 37/7206 0.0379972563868 ko00982 Drug metabolism - cytochrome P450 7/628 37/7206 0.0379972563868 ko05340 Primary immunodeficiency 6/628 30/7206 0.0417403769934 ko04930 Type II diabetes mellitus 9/628 54/7206 0.0491489450529 ko00950 Isoquinoline alkaloid biosynthesis 3/628 10/7206 0.0497120840343