ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	82/450	423/7206	1.28153766013e-21
ko04724	Glutamatergic synapse	47/450	152/7206	2.77908157351e-21
ko05033	Nicotine addiction	23/450	56/7206	5.29140762141e-14
ko04728	Dopaminergic synapse	40/450	185/7206	1.76677625006e-12
ko04713	Circadian entrainment	33/450	136/7206	6.05500159083e-12
ko04727	GABAergic synapse	28/450	110/7206	7.56493365571e-11
ko04721	Synaptic vesicle cycle	22/450	80/7206	1.75107562271e-09
ko05032	Morphine addiction	26/450	110/7206	2.08345271291e-09
ko04723	Retrograde endocannabinoid signaling	33/450	175/7206	6.95822379013e-09
ko04972	Pancreatic secretion	24/450	111/7206	5.62817729559e-08
ko04024	cAMP signaling pathway	42/450	279/7206	7.39911125728e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	19/450	74/7206	7.74268609006e-08
ko05031	Amphetamine addiction	21/450	91/7206	1.18462109702e-07
ko04911	Insulin secretion	24/450	117/7206	1.62385259755e-07
ko05030	Cocaine addiction	18/450	73/7206	3.32009314245e-07
ko04725	Cholinergic synapse	28/450	160/7206	5.06883402376e-07
ko04970	Salivary secretion	20/450	95/7206	1.14754754329e-06
ko04976	Bile secretion	17/450	80/7206	6.41716120004e-06
ko04726	Serotonergic synapse	23/450	137/7206	1.09946445665e-05
ko04921	Oxytocin signaling pathway	30/450	209/7206	1.48996139386e-05
ko04514	Cell adhesion molecules (CAMs)	22/450	130/7206	1.49804860044e-05
ko04261	Adrenergic signaling in cardiomyocytes	29/450	205/7206	2.68711828014e-05
ko04964	Proximal tubule bicarbonate reclamation	9/450	29/7206	4.33707282173e-05
ko04924	Renin secretion	16/450	86/7206	6.80405101861e-05
ko04730	Long-term depression	15/450	78/7206	7.70606664035e-05
ko04971	Gastric acid secretion	17/450	98/7206	0.000101566641892
ko04060	Cytokine-cytokine receptor interaction	1/450	191/7206	0.000102113889988
ko04978	Mineral absorption	10/450	40/7206	0.000126406230634
ko04720	Long-term potentiation	16/450	99/7206	0.000375176058547
ko04974	Protein digestion and absorption	15/450	96/7206	0.000817977816308
ko05016	Huntington's disease	3/450	215/7206	0.000866536824279
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/450	59/7206	0.000907220641932
ko04742	Taste transduction	11/450	61/7206	0.00121057103159
ko03040	Spliceosome	1/450	145/7206	0.00149418618544
ko04540	Gap junction	17/450	128/7206	0.0026519334763
ko04925	Aldosterone synthesis and secretion	15/450	105/7206	0.00316617458496
ko04010	MAPK signaling pathway	33/450	321/7206	0.00428893513357
ko05168	Herpes simplex infection	3/450	182/7206	0.00484536721501
ko05322	Systemic lupus erythematosus	2/450	151/7206	0.0059720375597
ko05162	Measles	1/450	120/7206	0.00680024800472
ko04217	Necroptosis	3/450	178/7206	0.00687498697481
ko04260	Cardiac muscle contraction	13/450	98/7206	0.00932337823597
ko04510	Focal adhesion	6/450	240/7206	0.00977601941747
ko04120	Ubiquitin mediated proteolysis	2/450	138/7206	0.0120453308354
ko04960	Aldosterone-regulated sodium reabsorption	7/450	41/7206	0.0124854540639
ko04020	Calcium signaling pathway	27/450	265/7206	0.0130446177243
ko05164	Influenza A	3/450	167/7206	0.0137086423525
ko04022	cGMP-PKG signaling pathway	23/450	216/7206	0.0140299170478
ko04973	Carbohydrate digestion and absorption	7/450	42/7206	0.0142019474328
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11/450	79/7206	0.0154840054888
ko05203	Viral carcinogenesis	8/450	277/7206	0.0155053593442
ko04141	Protein processing in endoplasmic reticulum	4/450	184/7206	0.0190708503729
ko04918	Thyroid hormone synthesis	11/450	86/7206	0.0212331364938
ko04614	Renin-angiotensin system	4/450	18/7206	0.0227960373004
ko05410	Hypertrophic cardiomyopathy (HCM)	12/450	100/7206	0.0330579357475
ko03013	RNA transport	4/450	166/7206	0.0342404592158
ko04550	Signaling pathways regulating pluripotency of stem cells	4/450	165/7206	0.0342446409119
ko05205	Proteoglycans in cancer	9/450	271/7206	0.0402306684796
ko05169	Epstein-Barr virus infection	6/450	206/7206	0.0407218830768
ko04915	Estrogen signaling pathway	14/450	131/7206	0.0431966395741
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/450	182/7206	0.043715631411
ko05166	HTLV-I infection	10/450	292/7206	0.0468505197303
ko04140	Autophagy - animal	4/450	164/7206	0.0474892837498