ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	206/1294	423/7206	8.48853698419e-51
ko04724	Glutamatergic synapse	89/1294	152/7206	1.22800417662e-29
ko05033	Nicotine addiction	48/1294	56/7206	2.46106471643e-28
ko05032	Morphine addiction	71/1294	110/7206	1.48243953014e-27
ko04713	Circadian entrainment	80/1294	136/7206	6.4465822229e-27
ko04727	GABAergic synapse	67/1294	110/7206	6.28597407231e-24
ko04725	Cholinergic synapse	80/1294	160/7206	9.58969563774e-21
ko04728	Dopaminergic synapse	86/1294	185/7206	1.42352489558e-19
ko04020	Calcium signaling pathway	107/1294	265/7206	2.50874426638e-18
ko04024	cAMP signaling pathway	110/1294	279/7206	9.07180738442e-18
ko04723	Retrograde endocannabinoid signaling	80/1294	175/7206	9.73487802282e-18
ko04721	Synaptic vesicle cycle	47/1294	80/7206	2.94344204622e-16
ko04911	Insulin secretion	59/1294	117/7206	8.02488856086e-16
ko04744	Phototransduction	28/1294	36/7206	7.0199336103e-15
ko04726	Serotonergic synapse	63/1294	137/7206	2.28538128904e-14
ko04921	Oxytocin signaling pathway	82/1294	209/7206	2.94252035957e-13
ko04742	Taste transduction	36/1294	61/7206	7.76279562521e-13
ko04970	Salivary secretion	46/1294	95/7206	8.16802254681e-12
ko03040	Spliceosome	2/1294	145/7206	2.22663268382e-10
ko03010	Ribosome	1/1294	129/7206	3.38704653681e-10
ko04261	Adrenergic signaling in cardiomyocytes	74/1294	205/7206	4.05627013572e-10
ko05031	Amphetamine addiction	42/1294	91/7206	4.50359199719e-10
ko04720	Long-term potentiation	44/1294	99/7206	7.81302042354e-10
ko05322	Systemic lupus erythematosus	5/1294	151/7206	4.44557503967e-08
ko04740	Olfactory transduction	35/1294	80/7206	6.95885514964e-08
ko04022	cGMP-PKG signaling pathway	71/1294	216/7206	7.27365920855e-08
ko04971	Gastric acid secretion	40/1294	98/7206	8.84664613243e-08
ko04925	Aldosterone synthesis and secretion	42/1294	105/7206	1.00042397552e-07
ko03013	RNA transport	7/1294	166/7206	1.70146669253e-07
ko04070	Phosphatidylinositol signaling system	42/1294	112/7206	7.23824850087e-07
ko04730	Long-term depression	32/1294	78/7206	1.63677846944e-06
ko04072	Phospholipase D signaling pathway	63/1294	197/7206	1.76676637912e-06
ko05203	Viral carcinogenesis	22/1294	277/7206	1.99134456808e-06
ko04360	Axon guidance	71/1294	233/7206	2.17046996594e-06
ko05168	Herpes simplex infection	11/1294	182/7206	3.19606163689e-06
ko04060	Cytokine-cytokine receptor interaction	13/1294	191/7206	9.14685677689e-06
ko05030	Cocaine addiction	29/1294	73/7206	1.00895653184e-05
ko04972	Pancreatic secretion	39/1294	111/7206	1.44608959782e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1294	74/7206	2.00937399531e-05
ko04976	Bile secretion	30/1294	80/7206	2.80144068394e-05
ko04745	Phototransduction - fly	18/1294	38/7206	2.94452344436e-05
ko04010	MAPK signaling pathway	87/1294	321/7206	3.80017772851e-05
ko04540	Gap junction	42/1294	128/7206	3.86769998163e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1294	79/7206	4.44054072934e-05
ko04110	Cell cycle	9/1294	145/7206	6.52721698604e-05
ko04514	Cell adhesion molecules (CAMs)	42/1294	130/7206	6.82977163628e-05
ko04141	Protein processing in endoplasmic reticulum	14/1294	184/7206	8.37682253221e-05
ko05164	Influenza A	12/1294	167/7206	8.85926725914e-05
ko04014	Ras signaling pathway	75/1294	279/7206	0.000168915395818
ko04924	Renin secretion	30/1294	86/7206	0.000170636345842
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1294	79/7206	0.000175052897192
ko04750	Inflammatory mediator regulation of TRP channels	39/1294	122/7206	0.000179370071149
ko04710	Circadian rhythm	18/1294	43/7206	0.000215133192353
ko04612	Antigen processing and presentation	3/1294	77/7206	0.000450316303352
ko00520	Amino sugar and nucleotide sugar metabolism	1/1294	55/7206	0.000543600375547
ko05414	Dilated cardiomyopathy	35/1294	112/7206	0.00067726855164
ko04621	NOD-like receptor signaling pathway	13/1294	157/7206	0.000716152642679
ko04923	Regulation of lipolysis in adipocytes	26/1294	77/7206	0.000817754297813
ko04966	Collecting duct acid secretion	12/1294	26/7206	0.000858779944689
ko03420	Nucleotide excision repair	1/1294	46/7206	0.00177928263025
ko04930	Type II diabetes mellitus	19/1294	54/7206	0.00213551257896
ko05140	Leishmaniasis	4/1294	75/7206	0.0021995610885
ko05169	Epstein-Barr virus infection	21/1294	206/7206	0.00228322872881
ko03022	Basal transcription factors	1/1294	44/7206	0.00268585996483
ko04964	Proximal tubule bicarbonate reclamation	12/1294	29/7206	0.00272193586614
ko05144	Malaria	1/1294	45/7206	0.00273694988397
ko00071	Fatty acid degradation	1/1294	45/7206	0.00273694988397
ko05110	Vibrio cholerae infection	21/1294	63/7206	0.00276393753505
ko04120	Ubiquitin mediated proteolysis	12/1294	138/7206	0.00332929060481
ko04915	Estrogen signaling pathway	37/1294	131/7206	0.00376379192692
ko05162	Measles	10/1294	120/7206	0.00380465121316
ko04622	RIG-I-like receptor signaling pathway	3/1294	62/7206	0.00416586240005
ko05133	Pertussis	6/1294	87/7206	0.00458817874458
ko04260	Cardiac muscle contraction	29/1294	98/7206	0.00489482362173
ko00590	Arachidonic acid metabolism	2/1294	52/7206	0.00548052094715
ko05231	Choline metabolism in cancer	37/1294	134/7206	0.00599022387356
ko03018	RNA degradation	6/1294	84/7206	0.00634410318931
ko05161	Hepatitis B	18/1294	173/7206	0.00672912865024
ko04973	Carbohydrate digestion and absorption	15/1294	42/7206	0.00707171609064
ko04371	Apelin signaling pathway	46/1294	177/7206	0.00714987517718
ko04270	Vascular smooth muscle contraction	41/1294	154/7206	0.00758368586002
ko04626	Plant-pathogen interaction	8/1294	18/7206	0.00841722953726
ko05131	Shigellosis	6/1294	82/7206	0.00874791594001
ko04115	p53 signaling pathway	5/1294	74/7206	0.00900707087794
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1294	59/7206	0.00933331481098
ko03410	Base excision repair	1/1294	38/7206	0.009415253369
ko05205	Proteoglycans in cancer	33/1294	271/7206	0.00980624289856
ko02010	ABC transporters	14/1294	39/7206	0.00998285259599
ko04658	Th1 and Th2 cell differentiation	8/1294	96/7206	0.0106338749307
ko04146	Peroxisome	7/1294	89/7206	0.0115640988076
ko00240	Pyrimidine metabolism	10/1294	110/7206	0.012018392017
ko04610	Complement and coagulation cascades	6/1294	79/7206	0.0120198658618
ko05410	Hypertrophic cardiomyopathy (HCM)	28/1294	100/7206	0.0121553691935
ko00280	Valine, leucine and isoleucine degradation	3/1294	54/7206	0.0123390854632
ko04960	Aldosterone-regulated sodium reabsorption	14/1294	41/7206	0.0124795164624
ko04922	Glucagon signaling pathway	34/1294	128/7206	0.0142601723241
ko04657	IL-17 signaling pathway	7/1294	87/7206	0.015850737142
ko04217	Necroptosis	20/1294	178/7206	0.0172846362268
ko04113	Meiosis - yeast	5/1294	70/7206	0.0176296613447
ko00330	Arginine and proline metabolism	4/1294	61/7206	0.0178576496842
ko04711	Circadian rhythm - fly	6/1294	13/7206	0.018037885335
ko00860	Porphyrin and chlorophyll metabolism	1/1294	34/7206	0.0219749021215
ko04912	GnRH signaling pathway	32/1294	122/7206	0.0230014947086
ko05166	HTLV-I infection	38/1294	292/7206	0.0238756603462
ko05145	Toxoplasmosis	13/1294	126/7206	0.0253406748588
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1294	14/7206	0.026863168275
ko00230	Purine metabolism	47/1294	194/7206	0.0286182170149
ko04214	Apoptosis - fly	6/1294	72/7206	0.0303075720403
ko00310	Lysine degradation	6/1294	73/7206	0.0305984852333
ko04064	NF-kappa B signaling pathway	9/1294	96/7206	0.0309953039215
ko04015	Rap1 signaling pathway	64/1294	278/7206	0.0310455195422
ko04142	Lysosome	17/1294	151/7206	0.0315250675926
ko05321	Inflammatory bowel disease (IBD)	4/1294	56/7206	0.0346146452003
ko00562	Inositol phosphate metabolism	24/1294	89/7206	0.0358051920441
ko05219	Bladder cancer	3/1294	48/7206	0.0359203703937
ko04932	Non-alcoholic fatty liver disease (NAFLD)	22/1294	182/7206	0.0394234912903
ko03015	mRNA surveillance pathway	9/1294	93/7206	0.040197225888
ko03320	PPAR signaling pathway	6/1294	69/7206	0.0409291535928
ko04666	Fc gamma R-mediated phagocytosis	31/1294	122/7206	0.0420625877512
ko05012	Parkinson's disease	18/1294	155/7206	0.0436076025893
ko05132	Salmonella infection	10/1294	98/7206	0.0461685997761