ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 32/309 79/7206 7.55741893983e-24 ko00980 Metabolism of xenobiotics by cytochrome P450 14/309 40/7206 4.49299878604e-10 ko05204 Chemical carcinogenesis 14/309 48/7206 6.83723457869e-09 ko00983 Drug metabolism - other enzymes 13/309 42/7206 1.07091630553e-08 ko00982 Drug metabolism - cytochrome P450 12/309 37/7206 2.20661182272e-08 ko04974 Protein digestion and absorption 18/309 96/7206 9.58420045624e-08 ko05150 Staphylococcus aureus infection 11/309 36/7206 1.73519748969e-07 ko00260 Glycine, serine and threonine metabolism 12/309 48/7206 5.421462821e-07 ko00380 Tryptophan metabolism 12/309 50/7206 8.74409126084e-07 ko00053 Ascorbate and aldarate metabolism 8/309 22/7206 1.97342117684e-06 ko00630 Glyoxylate and dicarboxylate metabolism 10/309 38/7206 2.94603061202e-06 ko04614 Renin-angiotensin system 7/309 18/7206 5.27159036537e-06 ko00830 Retinol metabolism 10/309 42/7206 7.8693089722e-06 ko00040 Pentose and glucuronate interconversions 8/309 26/7206 8.29343108175e-06 ko00620 Pyruvate metabolism 10/309 46/7206 1.87115765587e-05 ko00360 Phenylalanine metabolism 6/309 17/7206 4.90862155207e-05 ko00350 Tyrosine metabolism 8/309 33/7206 5.66641406315e-05 ko00340 Histidine metabolism 7/309 25/7206 6.14046029344e-05 ko00410 beta-Alanine metabolism 8/309 35/7206 8.9116661586e-05 ko04975 Fat digestion and absorption 8/309 35/7206 8.9116661586e-05 ko01200 Carbon metabolism 16/309 128/7206 0.000105533488092 ko00140 Steroid hormone biosynthesis 8/309 41/7206 0.000289040029402 ko00643 Styrene degradation 3/309 4/7206 0.000302512278102 ko00561 Glycerolipid metabolism 10/309 63/7206 0.000307088413566 ko05133 Pertussis 12/309 87/7206 0.000307140435788 ko00280 Valine, leucine and isoleucine degradation 9/309 54/7206 0.000421774232729 ko00480 Glutathione metabolism 9/309 55/7206 0.000485656651877 ko00640 Propanoate metabolism 7/309 34/7206 0.000492768463466 ko04976 Bile secretion 11/309 80/7206 0.000559726972921 ko00071 Fatty acid degradation 8/309 45/7206 0.000561631902042 ko03320 PPAR signaling pathway 10/309 69/7206 0.000650702141928 ko00330 Arginine and proline metabolism 9/309 61/7206 0.00105702585995 ko00100 Steroid biosynthesis 5/309 21/7206 0.00161923800618 ko04973 Carbohydrate digestion and absorption 7/309 42/7206 0.00184161226119 ko04977 Vitamin digestion and absorption 5/309 22/7206 0.00202292845503 ko04972 Pancreatic secretion 12/309 111/7206 0.0027265619869 ko04010 MAPK signaling pathway 4/309 321/7206 0.00280136247522 ko00860 Porphyrin and chlorophyll metabolism 6/309 34/7206 0.00288137467064 ko05034 Alcoholism 2/309 238/7206 0.00307075772517 ko00020 Citrate cycle (TCA cycle) 6/309 35/7206 0.00335469051681 ko04146 Peroxisome 10/309 89/7206 0.00457320581625 ko01524 Platinum drug resistance 9/309 76/7206 0.00495319889455 ko00720 Carbon fixation pathways in prokaryotes 4/309 17/7206 0.0050651023567 ko02010 ABC transporters 6/309 39/7206 0.00584152250162 ko04978 Mineral absorption 6/309 40/7206 0.00663069478383 ko04723 Retrograde endocannabinoid signaling 1/309 175/7206 0.0071672056344 ko00950 Isoquinoline alkaloid biosynthesis 3/309 10/7206 0.00748380643623 ko00120 Primary bile acid biosynthesis 4/309 20/7206 0.00931771886074 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/309 4/7206 0.0103834878705 ko00591 Linoleic acid metabolism 4/309 22/7206 0.0131527256019 ko00270 Cysteine and methionine metabolism 6/309 47/7206 0.0144505560926 ko04725 Cholinergic synapse 1/309 160/7206 0.0155150030365 ko00232 Caffeine metabolism 2/309 5/7206 0.0168176567785 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/309 5/7206 0.0168176567785 ko00281 Geraniol degradation 2/309 5/7206 0.0168176567785 ko04512 ECM-receptor interaction 8/309 79/7206 0.0193653121853 ko04360 Axon guidance 3/309 233/7206 0.0195184019682 ko00770 Pantothenate and CoA biosynthesis 3/309 14/7206 0.019991080271 ko03040 Spliceosome 1/309 145/7206 0.0215853372572 ko00250 Alanine, aspartate and glutamate metabolism 5/309 38/7206 0.0220614890476 ko00590 Arachidonic acid metabolism 6/309 52/7206 0.0229467490861 ko00650 Butanoate metabolism 4/309 26/7206 0.0235124996448 ko00362 Benzoate degradation 2/309 6/7206 0.0245174832698 ko04310 Wnt signaling pathway 2/309 181/7206 0.0248777550127 ko05166 HTLV-I infection 5/309 292/7206 0.0254625184396 ko01230 Biosynthesis of amino acids 8/309 85/7206 0.0287023570203 ko04713 Circadian entrainment 1/309 136/7206 0.0311262245878 ko04014 Ras signaling pathway 5/309 279/7206 0.0336397789057 ko05169 Epstein-Barr virus infection 3/309 206/7206 0.035804640866 ko05200 Pathways in cancer 12/309 492/7206 0.0370761358976 ko04260 Cardiac muscle contraction 9/309 98/7206 0.0374360032594 ko00010 Glycolysis / Gluconeogenesis 7/309 74/7206 0.0385347376473 ko05134 Legionellosis 7/309 74/7206 0.0385347376473 ko04144 Endocytosis 7/309 342/7206 0.0386480276248 ko04270 Vascular smooth muscle contraction 12/309 154/7206 0.0412481440019 ko00401 Novobiocin biosynthesis 1/309 1/7206 0.0428809325564 ko00740 Riboflavin metabolism 2/309 8/7206 0.0432433212421 ko04062 Chemokine signaling pathway 3/309 201/7206 0.0495854301959