ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/923	423/7206	1.04758546992e-44
ko04724	Glutamatergic synapse	75/923	152/7206	1.80380256051e-28
ko05033	Nicotine addiction	43/923	56/7206	6.30691296368e-28
ko05032	Morphine addiction	55/923	110/7206	1.75106214213e-21
ko04721	Synaptic vesicle cycle	45/923	80/7206	1.74709925776e-20
ko04727	GABAergic synapse	53/923	110/7206	8.46027624572e-20
ko04728	Dopaminergic synapse	70/923	185/7206	1.87322608017e-18
ko04713	Circadian entrainment	57/923	136/7206	1.24811123941e-17
ko04725	Cholinergic synapse	61/923	160/7206	2.11756197133e-16
ko04723	Retrograde endocannabinoid signaling	63/923	175/7206	1.72539745361e-15
ko04742	Taste transduction	32/923	61/7206	9.05074860852e-14
ko04024	cAMP signaling pathway	80/923	279/7206	6.77306639374e-13
ko04726	Serotonergic synapse	49/923	137/7206	3.43194573253e-12
ko04911	Insulin secretion	42/923	117/7206	1.08738550608e-10
ko05031	Amphetamine addiction	33/923	91/7206	8.27023397551e-09
ko04020	Calcium signaling pathway	67/923	265/7206	1.80164895572e-08
ko04921	Oxytocin signaling pathway	55/923	209/7206	8.20966355732e-08
ko03040	Spliceosome	1/923	145/7206	9.38866922214e-08
ko05030	Cocaine addiction	27/923	73/7206	1.18127071214e-07
ko04360	Axon guidance	59/923	233/7206	1.28519054866e-07
ko05203	Viral carcinogenesis	10/923	277/7206	1.77900478538e-07
ko04720	Long-term potentiation	32/923	99/7206	3.09255363267e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/923	74/7206	6.52048033101e-07
ko04261	Adrenergic signaling in cardiomyocytes	52/923	205/7206	6.83462630576e-07
ko04060	Cytokine-cytokine receptor interaction	5/923	191/7206	8.9640980461e-07
ko04514	Cell adhesion molecules (CAMs)	37/923	130/7206	1.65450746923e-06
ko05168	Herpes simplex infection	5/923	182/7206	2.72529623581e-06
ko05164	Influenza A	4/923	167/7206	3.06044372211e-06
ko04970	Salivary secretion	28/923	95/7206	1.45491144686e-05
ko04120	Ubiquitin mediated proteolysis	3/923	138/7206	1.47414931012e-05
ko04744	Phototransduction	15/923	36/7206	1.48392570555e-05
ko04010	MAPK signaling pathway	68/923	321/7206	1.67264659171e-05
ko03013	RNA transport	5/923	166/7206	1.69244964589e-05
ko04621	NOD-like receptor signaling pathway	5/923	157/7206	5.02701793934e-05
ko04540	Gap junction	33/923	128/7206	7.45345456705e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/923	14/7206	0.000103491929273
ko04966	Collecting duct acid secretion	11/923	26/7206	0.000177194530625
ko04730	Long-term depression	22/923	78/7206	0.000235257501841
ko05322	Systemic lupus erythematosus	6/923	151/7206	0.000312984786923
ko04141	Protein processing in endoplasmic reticulum	9/923	184/7206	0.000470091100315
ko04610	Complement and coagulation cascades	1/923	79/7206	0.00049868390866
ko03008	Ribosome biogenesis in eukaryotes	1/923	79/7206	0.00049868390866
ko05205	Proteoglycans in cancer	17/923	271/7206	0.000557357138985
ko04971	Gastric acid secretion	25/923	98/7206	0.000613971656749
ko04014	Ras signaling pathway	55/923	279/7206	0.000928085436763
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/923	79/7206	0.000944758073268
ko04925	Aldosterone synthesis and secretion	26/923	105/7206	0.000958411850984
ko04740	Olfactory transduction	21/923	80/7206	0.00105513696399
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/923	59/7206	0.00113294541466
ko04260	Cardiac muscle contraction	24/923	98/7206	0.00125462419035
ko05169	Epstein-Barr virus infection	12/923	206/7206	0.00138437698358
ko03018	RNA degradation	2/923	84/7206	0.00150781720563
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/923	182/7206	0.00153235616544
ko05162	Measles	5/923	120/7206	0.00219632330181
ko04972	Pancreatic secretion	26/923	111/7206	0.00223921252501
ko04022	cGMP-PKG signaling pathway	43/923	216/7206	0.00259664015224
ko01200	Carbon metabolism	6/923	128/7206	0.00310036883966
ko04612	Antigen processing and presentation	2/923	77/7206	0.00317800767167
ko05161	Hepatitis B	10/923	173/7206	0.0036939912468
ko05140	Leishmaniasis	2/923	75/7206	0.00468122377654
ko04110	Cell cycle	8/923	145/7206	0.00544473897273
ko00240	Pyrimidine metabolism	5/923	110/7206	0.00585665466809
ko05110	Vibrio cholerae infection	16/923	63/7206	0.00659346530609
ko04214	Apoptosis - fly	2/923	72/7206	0.00681020135314
ko00480	Glutathione metabolism	1/923	55/7206	0.00773871755212
ko04064	NF-kappa B signaling pathway	4/923	96/7206	0.00810199008398
ko04964	Proximal tubule bicarbonate reclamation	9/923	29/7206	0.00819359513606
ko04924	Renin secretion	20/923	86/7206	0.00823634067913
ko04072	Phospholipase D signaling pathway	38/923	197/7206	0.00905170131462
ko04915	Estrogen signaling pathway	27/923	131/7206	0.0114377098947
ko00590	Arachidonic acid metabolism	1/923	52/7206	0.0114552346791
ko04640	Hematopoietic cell lineage	2/923	64/7206	0.01384431209
ko05146	Amoebiasis	5/923	99/7206	0.0151314447165
ko05166	HTLV-I infection	24/923	292/7206	0.0155030518312
ko04146	Peroxisome	4/923	89/7206	0.015513980577
ko05418	Fluid shear stress and atherosclerosis	12/923	173/7206	0.0155715414091
ko04976	Bile secretion	18/923	80/7206	0.0167661185873
ko04630	Jak-STAT signaling pathway	8/923	132/7206	0.0172460130831
ko00330	Arginine and proline metabolism	2/923	61/7206	0.0198870368785
ko00561	Glycerolipid metabolism	2/923	63/7206	0.0207231019444
ko00310	Lysine degradation	3/923	73/7206	0.0211087228621
ko05414	Dilated cardiomyopathy	23/923	112/7206	0.0213246069808
ko00071	Fatty acid degradation	1/923	45/7206	0.0249484558256
ko00620	Pyruvate metabolism	1/923	46/7206	0.0250297344689
ko03420	Nucleotide excision repair	1/923	46/7206	0.0250297344689
ko05219	Bladder cancer	1/923	48/7206	0.0265849819138
ko04750	Inflammatory mediator regulation of TRP channels	24/923	122/7206	0.0281567347762
ko05034	Alcoholism	42/923	238/7206	0.0294339652934
ko04140	Autophagy - animal	12/923	164/7206	0.0327823510444
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/923	15/7206	0.0339887104245
ko00983	Drug metabolism - other enzymes	1/923	42/7206	0.0366632583516
ko03022	Basal transcription factors	1/923	44/7206	0.0378473671353
ko04668	TNF signaling pathway	8/923	120/7206	0.0389337746065
ko00280	Valine, leucine and isoleucine degradation	2/923	54/7206	0.0404914132922
ko05321	Inflammatory bowel disease (IBD)	2/923	56/7206	0.0415758698933
ko04015	Rap1 signaling pathway	47/923	278/7206	0.0435748496573
ko05016	Huntington's disease	18/923	215/7206	0.0487209139557