ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	95/495	423/7206	5.7163801245e-27
ko05033	Nicotine addiction	32/495	56/7206	2.14379948669e-23
ko04724	Glutamatergic synapse	51/495	152/7206	6.07217453128e-23
ko04728	Dopaminergic synapse	48/495	185/7206	1.79556246416e-16
ko04721	Synaptic vesicle cycle	31/495	80/7206	2.14928538996e-16
ko04727	GABAergic synapse	35/495	110/7206	3.0300548046e-15
ko05032	Morphine addiction	34/495	110/7206	2.02366251711e-14
ko04723	Retrograde endocannabinoid signaling	43/495	175/7206	5.94204960348e-14
ko04713	Circadian entrainment	36/495	136/7206	6.58707319847e-13
ko04725	Cholinergic synapse	34/495	160/7206	1.85766548408e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	22/495	74/7206	2.059292739e-09
ko05030	Cocaine addiction	21/495	73/7206	9.29486519326e-09
ko05031	Amphetamine addiction	23/495	91/7206	2.76658399061e-08
ko04726	Serotonergic synapse	29/495	137/7206	3.27330167853e-08
ko04024	cAMP signaling pathway	45/495	279/7206	4.58460123589e-08
ko04911	Insulin secretion	25/495	117/7206	2.4405099576e-07
ko04261	Adrenergic signaling in cardiomyocytes	34/495	205/7206	1.46622654429e-06
ko04514	Cell adhesion molecules (CAMs)	24/495	130/7206	6.62719653902e-06
ko04010	MAPK signaling pathway	44/495	321/7206	7.58226920542e-06
ko04742	Taste transduction	15/495	61/7206	1.06983604778e-05
ko04921	Oxytocin signaling pathway	32/495	209/7206	1.76092324439e-05
ko04060	Cytokine-cytokine receptor interaction	1/495	191/7206	3.05609239567e-05
ko04966	Collecting duct acid secretion	9/495	26/7206	3.44049618228e-05
ko04720	Long-term potentiation	19/495	99/7206	3.45474164562e-05
ko04730	Long-term depression	16/495	78/7206	6.18064847531e-05
ko05164	Influenza A	1/495	167/7206	0.000144441842133
ko04970	Salivary secretion	17/495	95/7206	0.000217533333082
ko05110	Vibrio cholerae infection	13/495	63/7206	0.000281602565663
ko03040	Spliceosome	1/495	145/7206	0.000686616393316
ko04145	Phagosome	23/495	162/7206	0.000763827077069
ko04120	Ubiquitin mediated proteolysis	1/495	138/7206	0.000995378257487
ko04540	Gap junction	19/495	128/7206	0.00119691560827
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/495	14/7206	0.00178319781747
ko05322	Systemic lupus erythematosus	2/495	151/7206	0.00290879488833
ko05205	Proteoglycans in cancer	7/495	271/7206	0.00296163565495
ko04972	Pancreatic secretion	16/495	111/7206	0.00392069059447
ko03013	RNA transport	3/495	166/7206	0.00476135439928
ko05203	Viral carcinogenesis	8/495	277/7206	0.0050051513644
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/495	92/7206	0.00517027502956
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/495	59/7206	0.00633481293648
ko05168	Herpes simplex infection	4/495	182/7206	0.00709381592513
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/495	182/7206	0.00709381592513
ko04260	Cardiac muscle contraction	14/495	98/7206	0.00763242658283
ko01200	Carbon metabolism	2/495	128/7206	0.0120959793248
ko04360	Axon guidance	26/495	233/7206	0.0121030401967
ko04964	Proximal tubule bicarbonate reclamation	6/495	29/7206	0.0124585237523
ko00564	Glycerophospholipid metabolism	1/495	99/7206	0.0143444275269
ko04924	Renin secretion	12/495	86/7206	0.016083376938
ko05034	Alcoholism	26/495	238/7206	0.0180348764256
ko05323	Rheumatoid arthritis	12/495	89/7206	0.0197164313534
ko04915	Estrogen signaling pathway	16/495	131/7206	0.0219546770915
ko04976	Bile secretion	11/495	80/7206	0.0233767666689
ko04971	Gastric acid secretion	13/495	98/7206	0.023493508598
ko04621	NOD-like receptor signaling pathway	4/495	157/7206	0.0249416229918
ko05016	Huntington's disease	7/495	215/7206	0.0284164525597
ko03018	RNA degradation	1/495	84/7206	0.0294625311852
ko04146	Peroxisome	1/495	89/7206	0.0310576174157
ko04020	Calcium signaling pathway	27/495	265/7206	0.0349948732746
ko04022	cGMP-PKG signaling pathway	23/495	216/7206	0.0387377874069
ko04071	Sphingolipid signaling pathway	18/495	162/7206	0.0396300443178
ko03008	Ribosome biogenesis in eukaryotes	1/495	79/7206	0.0426090526802
ko04110	Cell cycle	4/495	145/7206	0.0457254537123
ko04350	TGF-beta signaling pathway	2/495	103/7206	0.0471334022525