ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 22/151 191/7206 4.86932855572e-11 ko04380 Osteoclast differentiation 17/151 134/7206 2.02838140421e-09 ko05164 Influenza A 18/151 167/7206 9.40114119109e-09 ko04621 NOD-like receptor signaling pathway 17/151 157/7206 2.33145947014e-08 ko05162 Measles 15/151 120/7206 2.34545627902e-08 ko04610 Complement and coagulation cascades 12/151 79/7206 7.07925685157e-08 ko04620 Toll-like receptor signaling pathway 13/151 100/7206 1.32566068628e-07 ko04668 TNF signaling pathway 14/151 120/7206 1.70439311819e-07 ko04630 Jak-STAT signaling pathway 14/151 132/7206 5.61634903247e-07 ko05150 Staphylococcus aureus infection 8/151 36/7206 5.68303646588e-07 ko05131 Shigellosis 11/151 82/7206 9.26505542841e-07 ko05168 Herpes simplex infection 16/151 182/7206 1.10648537108e-06 ko05321 Inflammatory bowel disease (IBD) 9/151 56/7206 2.00656227257e-06 ko05160 Hepatitis C 14/151 153/7206 3.3623751677e-06 ko04064 NF-kappa B signaling pathway 11/151 96/7206 4.53675781474e-06 ko04622 RIG-I-like receptor signaling pathway 9/151 62/7206 4.82728719116e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/151 191/7206 9.86261911683e-06 ko05133 Pertussis 10/151 87/7206 1.21686073199e-05 ko05161 Hepatitis B 14/151 173/7206 1.40816670228e-05 ko04623 Cytosolic DNA-sensing pathway 7/151 41/7206 1.90900104651e-05 ko04210 Apoptosis 14/151 180/7206 2.20991285542e-05 ko05140 Leishmaniasis 9/151 75/7206 2.3700811721e-05 ko05132 Salmonella infection 10/151 98/7206 3.4982673991e-05 ko04062 Chemokine signaling pathway 14/151 201/7206 7.49787104213e-05 ko05142 Chagas disease (American trypanosomiasis) 11/151 130/7206 8.11781814882e-05 ko04672 Intestinal immune network for IgA production 6/151 37/7206 0.000104182914993 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/151 135/7206 0.000114275841235 ko05134 Legionellosis 8/151 74/7206 0.000144368929502 ko04660 T cell receptor signaling pathway 10/151 124/7206 0.000256026837859 ko05145 Toxoplasmosis 10/151 126/7206 0.00029167254944 ko05144 Malaria 6/151 45/7206 0.000317963510087 ko05340 Primary immunodeficiency 5/151 30/7206 0.000352902776809 ko04659 Th17 cell differentiation 9/151 106/7206 0.000356934181055 ko05323 Rheumatoid arthritis 8/151 89/7206 0.000519187016241 ko05152 Tuberculosis 12/151 187/7206 0.000527051729396 ko04658 Th1 and Th2 cell differentiation 8/151 96/7206 0.000861720928068 ko04666 Fc gamma R-mediated phagocytosis 9/151 122/7206 0.000998017491864 ko04217 Necroptosis 11/151 178/7206 0.00122768238295 ko04932 Non-alcoholic fatty liver disease (NAFLD) 11/151 182/7206 0.0014697622593 ko05212 Pancreatic cancer 7/151 83/7206 0.00169245194213 ko04662 B cell receptor signaling pathway 7/151 88/7206 0.00237245028958 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/151 92/7206 0.00305435672655 ko05169 Epstein-Barr virus infection 11/151 206/7206 0.00387846873893 ko04670 Leukocyte transendothelial migration 9/151 151/7206 0.00432142446078 ko05130 Pathogenic Escherichia coli infection 6/151 77/7206 0.00534829925945 ko04931 Insulin resistance 8/151 137/7206 0.00791568187942 ko04917 Prolactin signaling pathway 6/151 87/7206 0.00960918193982 ko05166 HTLV-I infection 13/151 292/7206 0.00989835111153 ko04920 Adipocytokine signaling pathway 6/151 89/7206 0.0106886779162 ko04650 Natural killer cell mediated cytotoxicity 6/151 97/7206 0.0158724562291 ko05100 Bacterial invasion of epithelial cells 6/151 99/7206 0.0174000352981 ko05219 Bladder cancer 4/151 48/7206 0.0176524689316 ko04611 Platelet activation 8/151 163/7206 0.020913122907 ko04612 Antigen processing and presentation 5/151 77/7206 0.0223305500846 ko04810 Regulation of actin cytoskeleton 11/151 264/7206 0.0258510490691 ko05220 Chronic myeloid leukemia 5/151 85/7206 0.0325002248279 ko04657 IL-17 signaling pathway 5/151 87/7206 0.0354285734958 ko00254 Aflatoxin biosynthesis 1/151 2/7206 0.0414732653005 ko00660 C5-Branched dibasic acid metabolism 1/151 2/7206 0.0414732653005