ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/371 191/7206 2.10162260323e-09 ko04610 Complement and coagulation cascades 19/371 79/7206 1.0803413118e-08 ko05150 Staphylococcus aureus infection 13/371 36/7206 1.13762386174e-08 ko04380 Osteoclast differentiation 25/371 134/7206 1.4071172593e-08 ko05340 Primary immunodeficiency 11/371 30/7206 1.31093172607e-07 ko04650 Natural killer cell mediated cytotoxicity 17/371 97/7206 7.42627905966e-06 ko05144 Malaria 11/371 45/7206 1.20993822494e-05 ko04064 NF-kappa B signaling pathway 16/371 96/7206 2.65336622388e-05 ko04660 T cell receptor signaling pathway 18/371 124/7206 5.75701018113e-05 ko04137 Mitophagy - animal 14/371 82/7206 6.42877690994e-05 ko04640 Hematopoietic cell lineage 12/371 64/7206 8.37279628763e-05 ko05323 Rheumatoid arthritis 14/371 89/7206 0.000160658555331 ko04514 Cell adhesion molecules (CAMs) 17/371 130/7206 0.000336095546909 ko05167 Kaposi's sarcoma-associated herpesvirus infection 22/371 191/7206 0.000341182332052 ko00120 Primary bile acid biosynthesis 6/371 20/7206 0.000374245252161 ko05140 Leishmaniasis 12/371 75/7206 0.000399098467104 ko04672 Intestinal immune network for IgA production 8/371 37/7206 0.000473561120383 ko04146 Peroxisome 13/371 89/7206 0.000575671120343 ko04621 NOD-like receptor signaling pathway 19/371 157/7206 0.000645362050116 ko04659 Th17 cell differentiation 14/371 106/7206 0.00100380448573 ko04670 Leukocyte transendothelial migration 18/371 151/7206 0.00102178264564 ko04658 Th1 and Th2 cell differentiation 13/371 96/7206 0.00119280690548 ko05418 Fluid shear stress and atherosclerosis 19/371 173/7206 0.00148012066783 ko04620 Toll-like receptor signaling pathway 13/371 100/7206 0.00174464250591 ko00071 Fatty acid degradation 8/371 45/7206 0.00184412917415 ko04611 Platelet activation 18/371 163/7206 0.00189035815138 ko05321 Inflammatory bowel disease (IBD) 9/371 56/7206 0.00203176688004 ko00592 alpha-Linolenic acid metabolism 5/371 19/7206 0.00224750707408 ko05034 Alcoholism 3/371 238/7206 0.00252805945387 ko05168 Herpes simplex infection 19/371 182/7206 0.00315342634005 ko04550 Signaling pathways regulating pluripotency of stem cells 1/371 165/7206 0.00347704628446 ko05164 Influenza A 18/371 167/7206 0.00362399373967 ko05152 Tuberculosis 19/371 187/7206 0.00390675845369 ko04622 RIG-I-like receptor signaling pathway 9/371 62/7206 0.004146808515 ko05162 Measles 14/371 120/7206 0.00497491836465 ko04612 Antigen processing and presentation 10/371 77/7206 0.00580853651757 ko04728 Dopaminergic synapse 2/371 185/7206 0.00619914637382 ko04110 Cell cycle 1/371 145/7206 0.00700239411537 ko04630 Jak-STAT signaling pathway 14/371 132/7206 0.00862443321379 ko04723 Retrograde endocannabinoid signaling 2/371 175/7206 0.00872398147321 ko00982 Drug metabolism - cytochrome P450 6/371 37/7206 0.0107149875024 ko04666 Fc gamma R-mediated phagocytosis 13/371 122/7206 0.0112279564881 ko00950 Isoquinoline alkaloid biosynthesis 3/371 10/7206 0.0123892132721 ko05133 Pertussis 10/371 87/7206 0.0134632127677 ko05145 Toxoplasmosis 13/371 126/7206 0.0137885276482 ko03010 Ribosome 1/371 129/7206 0.0146979051157 ko05020 Prion diseases 6/371 40/7206 0.0155492708878 ko05132 Salmonella infection 11/371 98/7206 0.0170317905864 ko04722 Neurotrophin signaling pathway 2/371 160/7206 0.0174870767184 ko04390 Hippo signaling pathway 3/371 188/7206 0.0186712239644 ko00051 Fructose and mannose metabolism 6/371 42/7206 0.0195038478568 ko00480 Glutathione metabolism 7/371 55/7206 0.0218073427251 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/371 5/7206 0.0238330090882 ko03320 PPAR signaling pathway 8/371 69/7206 0.0245797977781 ko00350 Tyrosine metabolism 5/371 33/7206 0.0254347690617 ko04310 Wnt signaling pathway 3/371 181/7206 0.0258011465647 ko04145 Phagosome 15/371 162/7206 0.0280994623219 ko00620 Pyruvate metabolism 6/371 46/7206 0.0293544867033 ko00270 Cysteine and methionine metabolism 6/371 47/7206 0.0322471014372 ko01212 Fatty acid metabolism 7/371 60/7206 0.0334024166876 ko04360 Axon guidance 5/371 233/7206 0.0335098426438 ko04916 Melanogenesis 2/371 142/7206 0.0344270087259 ko04910 Insulin signaling pathway 3/371 172/7206 0.0354335352635 ko05224 Breast cancer 3/371 174/7206 0.035593005857 ko01040 Biosynthesis of unsaturated fatty acids 4/371 25/7206 0.0371003300337 ko04012 ErbB signaling pathway 1/371 109/7206 0.0452039199232 ko04662 B cell receptor signaling pathway 9/371 88/7206 0.0457292030277 ko04972 Pancreatic secretion 1/371 111/7206 0.0464108087932 ko00710 Carbon fixation in photosynthetic organisms 4/371 27/7206 0.0475191458428 ko04713 Circadian entrainment 2/371 136/7206 0.0482862242907 ko03013 RNA transport 3/371 166/7206 0.0487589249681 ko00590 Arachidonic acid metabolism 6/371 52/7206 0.0494546280322