ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	37/591	56/7206	2.17038221315e-27
ko04724	Glutamatergic synapse	58/591	152/7206	2.72206996318e-25
ko04080	Neuroactive ligand-receptor interaction	102/591	423/7206	3.77489605925e-25
ko04728	Dopaminergic synapse	54/591	185/7206	1.93802857028e-17
ko04727	GABAergic synapse	39/591	110/7206	4.75786240179e-16
ko05032	Morphine addiction	39/591	110/7206	4.75786240179e-16
ko04721	Synaptic vesicle cycle	33/591	80/7206	4.93956060797e-16
ko04723	Retrograde endocannabinoid signaling	48/591	175/7206	1.88215633874e-14
ko04713	Circadian entrainment	40/591	136/7206	2.55669941111e-13
ko04024	cAMP signaling pathway	61/591	279/7206	3.92946195459e-13
ko04725	Cholinergic synapse	43/591	160/7206	9.90660800695e-13
ko04911	Insulin secretion	33/591	117/7206	1.15913636468e-10
ko05030	Cocaine addiction	24/591	73/7206	1.3846335268e-09
ko04261	Adrenergic signaling in cardiomyocytes	43/591	205/7206	5.36280274573e-09
ko04514	Cell adhesion molecules (CAMs)	32/591	130/7206	9.2893325336e-09
ko04726	Serotonergic synapse	32/591	137/7206	3.61423001594e-08
ko05031	Amphetamine addiction	25/591	91/7206	3.87017500877e-08
ko04921	Oxytocin signaling pathway	41/591	209/7206	1.03445331991e-07
ko04020	Calcium signaling pathway	48/591	265/7206	1.25596700481e-07
ko04010	MAPK signaling pathway	53/591	321/7206	6.04727465738e-07
ko04260	Cardiac muscle contraction	22/591	98/7206	1.00229170348e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/591	79/7206	1.4184725987e-05
ko04970	Salivary secretion	21/591	95/7206	2.04468802095e-05
ko05203	Viral carcinogenesis	6/591	277/7206	2.79688289945e-05
ko05205	Proteoglycans in cancer	6/591	271/7206	3.92713096985e-05
ko04720	Long-term potentiation	21/591	99/7206	3.94721383725e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	17/591	74/7206	7.46061802468e-05
ko04742	Taste transduction	15/591	61/7206	8.59961111548e-05
ko03040	Spliceosome	1/591	145/7206	9.04135865436e-05
ko04060	Cytokine-cytokine receptor interaction	3/591	191/7206	0.000136289796876
ko04730	Long-term depression	17/591	78/7206	0.000149588352933
ko04744	Phototransduction	10/591	36/7206	0.000456522037645
ko04972	Pancreatic secretion	20/591	111/7206	0.000675571551258
ko05168	Herpes simplex infection	4/591	182/7206	0.000928715964244
ko04930	Type II diabetes mellitus	12/591	54/7206	0.00115298580795
ko04120	Ubiquitin mediated proteolysis	2/591	138/7206	0.00137575585864
ko04621	NOD-like receptor signaling pathway	3/591	157/7206	0.00167170292595
ko04964	Proximal tubule bicarbonate reclamation	8/591	29/7206	0.00177818240512
ko04072	Phospholipase D signaling pathway	29/591	197/7206	0.0021255522648
ko04360	Axon guidance	33/591	233/7206	0.002134862224
ko04022	cGMP-PKG signaling pathway	31/591	216/7206	0.0022077685987
ko05164	Influenza A	4/591	167/7206	0.00254435489364
ko04350	TGF-beta signaling pathway	1/591	103/7206	0.00304918602506
ko04915	Estrogen signaling pathway	21/591	131/7206	0.00313040614248
ko05414	Dilated cardiomyopathy	18/591	112/7206	0.00486789359878
ko04973	Carbohydrate digestion and absorption	9/591	42/7206	0.0060379100182
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/591	59/7206	0.00764263287528
ko05410	Hypertrophic cardiomyopathy (HCM)	16/591	100/7206	0.00880251240377
ko04141	Protein processing in endoplasmic reticulum	6/591	184/7206	0.00931358956362
ko03013	RNA transport	5/591	166/7206	0.00949011774108
ko05322	Systemic lupus erythematosus	4/591	151/7206	0.00977177054802
ko05034	Alcoholism	31/591	238/7206	0.0109336821736
ko04540	Gap junction	19/591	128/7206	0.0132266395184
ko04110	Cell cycle	4/591	145/7206	0.0132359649084
ko04971	Gastric acid secretion	15/591	98/7206	0.0152853649709
ko04966	Collecting duct acid secretion	6/591	26/7206	0.0165241335623
ko04925	Aldosterone synthesis and secretion	16/591	105/7206	0.0175852703846
ko05010	Alzheimer's disease	26/591	202/7206	0.0188049354764
ko04071	Sphingolipid signaling pathway	22/591	162/7206	0.0191297231564
ko05169	Epstein-Barr virus infection	8/591	206/7206	0.0196244163359
ko04612	Antigen processing and presentation	1/591	77/7206	0.0197518758378
ko03008	Ribosome biogenesis in eukaryotes	1/591	79/7206	0.0204483707608
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/591	14/7206	0.02307200528
ko04630	Jak-STAT signaling pathway	4/591	132/7206	0.0241991063229
ko04214	Apoptosis - fly	1/591	72/7206	0.0286793192331
ko05166	HTLV-I infection	14/591	292/7206	0.0289426351255
ko04146	Peroxisome	2/591	89/7206	0.032245199643
ko04014	Ras signaling pathway	33/591	279/7206	0.0334948391947
ko00240	Pyrimidine metabolism	3/591	110/7206	0.0336880774141
ko04217	Necroptosis	7/591	178/7206	0.0366582399715
ko04978	Mineral absorption	7/591	40/7206	0.0417581328414
ko03018	RNA degradation	2/591	84/7206	0.0453495902948
ko05161	Hepatitis B	7/591	173/7206	0.0479622294948