ko pathway ratio_in_study ratio_in_pop p_value ko04727 GABAergic synapse 9/96 110/7206 1.38771109047e-05 ko05032 Morphine addiction 9/96 110/7206 1.38771109047e-05 ko04072 Phospholipase D signaling pathway 11/96 197/7206 5.58128577502e-05 ko05231 Choline metabolism in cancer 9/96 134/7206 6.70490478712e-05 ko04724 Glutamatergic synapse 9/96 152/7206 0.000176986971106 ko04914 Progesterone-mediated oocyte maturation 7/96 104/7206 0.000443137933459 ko04723 Retrograde endocannabinoid signaling 9/96 175/7206 0.00050525974806 ko04911 Insulin secretion 7/96 117/7206 0.000899106217409 ko04024 cAMP signaling pathway 11/96 279/7206 0.00113587488571 ko04666 Fc gamma R-mediated phagocytosis 7/96 122/7206 0.00115060723958 ko04742 Taste transduction 5/96 61/7206 0.00124718120534 ko04725 Cholinergic synapse 8/96 160/7206 0.00125522420963 ko01522 Endocrine resistance 7/96 124/7206 0.00126545480693 ko05213 Endometrial cancer 5/96 62/7206 0.00134246375595 ko04062 Chemokine signaling pathway 9/96 201/7206 0.00135996133454 ko04915 Estrogen signaling pathway 7/96 131/7206 0.00173983104107 ko04910 Insulin signaling pathway 8/96 172/7206 0.00199008108122 ko04925 Aldosterone synthesis and secretion 6/96 105/7206 0.00266379625782 ko01521 EGFR tyrosine kinase inhibitor resistance 6/96 106/7206 0.0027937740906 ko04012 ErbB signaling pathway 6/96 109/7206 0.00321236252967 ko04923 Regulation of lipolysis in adipocytes 5/96 77/7206 0.00350464917366 ko04070 Phosphatidylinositol signaling system 6/96 112/7206 0.00367616460183 ko05214 Glioma 5/96 79/7206 0.00391526119936 ko04270 Vascular smooth muscle contraction 7/96 154/7206 0.00432054390079 ko04011 MAPK signaling pathway - yeast 4/96 53/7206 0.0052597614178 ko04912 GnRH signaling pathway 6/96 122/7206 0.00558606288066 ko04213 Longevity regulating pathway - multiple species 5/96 86/7206 0.00562497226152 ko05210 Colorectal cancer 5/96 86/7206 0.00562497226152 ko00562 Inositol phosphate metabolism 5/96 89/7206 0.00649827415858 ko04320 Dorso-ventral axis formation 3/96 31/7206 0.0078616979322 ko04010 MAPK signaling pathway 10/96 321/7206 0.0100696568561 ko05223 Non-small cell lung cancer 4/96 66/7206 0.0113565354803 ko04139 Mitophagy - yeast 3/96 37/7206 0.0128319488553 ko05215 Prostate cancer 5/96 111/7206 0.0159756956251 ko05414 Dilated cardiomyopathy 5/96 112/7206 0.0165504400655 ko04973 Carbohydrate digestion and absorption 3/96 42/7206 0.0180767717985 ko04261 Adrenergic signaling in cardiomyocytes 7/96 205/7206 0.019195080404 ko04722 Neurotrophin signaling pathway 6/96 160/7206 0.0196091576406 ko04611 Platelet activation 6/96 163/7206 0.0212781551248 ko04211 Longevity regulating pathway 5/96 123/7206 0.0237991735119 ko05212 Pancreatic cancer 4/96 83/7206 0.0244232811495 ko04020 Calcium signaling pathway 8/96 265/7206 0.0245199692301 ko04022 cGMP-PKG signaling pathway 7/96 216/7206 0.0247459005484 ko05220 Chronic myeloid leukemia 4/96 85/7206 0.0263793495502 ko04924 Renin secretion 4/96 86/7206 0.0273917581982 ko05224 Breast cancer 6/96 174/7206 0.0282189069519 ko04917 Prolactin signaling pathway 4/96 87/7206 0.0284272054136 ko04015 Rap1 signaling pathway 8/96 278/7206 0.0314363911008 ko04713 Circadian entrainment 5/96 136/7206 0.0346898804669 ko04930 Type II diabetes mellitus 3/96 54/7206 0.034858103363 ko04360 Axon guidance 7/96 233/7206 0.0353575813045 ko04726 Serotonergic synapse 5/96 137/7206 0.0356368201633 ko04728 Dopaminergic synapse 6/96 185/7206 0.0365196816636 ko04970 Salivary secretion 4/96 95/7206 0.0375485641083 ko05033 Nicotine addiction 3/96 56/7206 0.038227818881 ko05211 Renal cell carcinoma 4/96 96/7206 0.0387942128056 ko04919 Thyroid hormone signaling pathway 5/96 143/7206 0.0416545702438 ko04720 Long-term potentiation 4/96 99/7206 0.042672468237 ko00564 Glycerophospholipid metabolism 4/96 99/7206 0.042672468237 ko04144 Endocytosis 9/96 342/7206 0.0469578952565