ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 17/224 152/7206 4.24697799766e-06 ko04020 Calcium signaling pathway 23/224 265/7206 7.05223417852e-06 ko04070 Phosphatidylinositol signaling system 14/224 112/7206 8.44256799297e-06 ko05031 Amphetamine addiction 12/224 91/7206 2.18427375939e-05 ko04720 Long-term potentiation 12/224 99/7206 5.13901280328e-05 ko04911 Insulin secretion 13/224 117/7206 6.31545981102e-05 ko04725 Cholinergic synapse 15/224 160/7206 0.000125352565768 ko04745 Phototransduction - fly 7/224 38/7206 0.000141592129564 ko04713 Circadian entrainment 13/224 136/7206 0.000292938581439 ko04022 cGMP-PKG signaling pathway 17/224 216/7206 0.000377348114207 ko04925 Aldosterone synthesis and secretion 11/224 105/7206 0.000390322853955 ko05110 Vibrio cholerae infection 8/224 63/7206 0.000682144143915 ko04921 Oxytocin signaling pathway 16/224 209/7206 0.000758481449269 ko04726 Serotonergic synapse 12/224 137/7206 0.00109327440204 ko04924 Renin secretion 9/224 86/7206 0.00132531860192 ko05010 Alzheimer's disease 15/224 202/7206 0.00150313186618 ko04728 Dopaminergic synapse 14/224 185/7206 0.00179763882502 ko05014 Amyotrophic lateral sclerosis (ALS) 8/224 74/7206 0.00198146662065 ko04080 Neuroactive ligand-receptor interaction 25/224 423/7206 0.00201910575873 ko04922 Glucagon signaling pathway 11/224 128/7206 0.00204097036628 ko04727 GABAergic synapse 10/224 110/7206 0.00213364043199 ko04740 Olfactory transduction 8/224 80/7206 0.00325067694985 ko04750 Inflammatory mediator regulation of TRP channels 10/224 122/7206 0.00453976934407 ko00562 Inositol phosphate metabolism 8/224 89/7206 0.00624328964727 ko05032 Morphine addiction 9/224 110/7206 0.00704809880021 ko04710 Circadian rhythm 5/224 43/7206 0.0102102285301 ko04971 Gastric acid secretion 8/224 98/7206 0.0109756012634 ko04114 Oocyte meiosis 10/224 139/7206 0.0111241266318 ko04721 Synaptic vesicle cycle 7/224 80/7206 0.0118547641524 ko04626 Plant-pathogen interaction 3/224 18/7206 0.0171256551093 ko04540 Gap junction 9/224 128/7206 0.0179487458775 ko04514 Cell adhesion molecules (CAMs) 9/224 130/7206 0.0196626161258 ko00680 Methane metabolism 4/224 34/7206 0.0203001456424 ko00010 Glycolysis / Gluconeogenesis 6/224 74/7206 0.0270074859797 ko04970 Salivary secretion 7/224 95/7206 0.0279855353335 ko05033 Nicotine addiction 5/224 56/7206 0.029334154348 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/224 1/7206 0.0310852067722 ko04360 Axon guidance 13/224 233/7206 0.0342829087868 ko05230 Central carbon metabolism in cancer 6/224 81/7206 0.0396498686779 ko00051 Fructose and mannose metabolism 4/224 42/7206 0.0404764745421 ko04916 Melanogenesis 9/224 142/7206 0.0432949939369 ko04966 Collecting duct acid secretion 3/224 26/7206 0.045538370179