ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/522	56/7206	6.0076578893e-24
ko05032	Morphine addiction	44/522	110/7206	1.53398319828e-22
ko04724	Glutamatergic synapse	50/522	152/7206	4.93641150221e-21
ko04080	Neuroactive ligand-receptor interaction	88/522	423/7206	7.81766094651e-21
ko04744	Phototransduction	24/522	36/7206	1.45006762828e-19
ko04727	GABAergic synapse	39/522	110/7206	6.46889018166e-18
ko04723	Retrograde endocannabinoid signaling	48/522	175/7206	1.3564640707e-16
ko04713	Circadian entrainment	39/522	136/7206	2.22195147613e-14
ko04728	Dopaminergic synapse	44/522	185/7206	6.87202191914e-13
ko04024	cAMP signaling pathway	54/522	279/7206	1.08148091503e-11
ko04721	Synaptic vesicle cycle	24/522	80/7206	9.06659096958e-10
ko04725	Cholinergic synapse	34/522	160/7206	7.34756352987e-09
ko04911	Insulin secretion	28/522	117/7206	1.03975744685e-08
ko05030	Cocaine addiction	21/522	73/7206	2.3783302748e-08
ko04742	Taste transduction	19/522	61/7206	2.66288187931e-08
ko04921	Oxytocin signaling pathway	36/522	209/7206	8.54600236487e-07
ko04020	Calcium signaling pathway	41/522	265/7206	2.67934128028e-06
ko04726	Serotonergic synapse	26/522	137/7206	4.27921159953e-06
ko05031	Amphetamine addiction	20/522	91/7206	5.59251159832e-06
ko04261	Adrenergic signaling in cardiomyocytes	33/522	205/7206	1.25858100053e-05
ko05203	Viral carcinogenesis	4/522	277/7206	1.45700178728e-05
ko04010	MAPK signaling pathway	44/522	321/7206	3.44833313153e-05
ko04970	Salivary secretion	19/522	95/7206	3.94244136922e-05
ko04720	Long-term potentiation	19/522	99/7206	7.14252236275e-05
ko04060	Cytokine-cytokine receptor interaction	2/522	191/7206	0.000103383571071
ko04072	Phospholipase D signaling pathway	30/522	197/7206	0.000114874185579
ko03040	Spliceosome	1/522	145/7206	0.000478987939033
ko04740	Olfactory transduction	15/522	80/7206	0.000527450684057
ko05205	Proteoglycans in cancer	7/522	271/7206	0.00113471747993
ko04730	Long-term depression	14/522	78/7206	0.00125548096615
ko05162	Measles	1/522	120/7206	0.00210603525215
ko04260	Cardiac muscle contraction	16/522	98/7206	0.00225904743464
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/522	14/7206	0.00226053383769
ko05414	Dilated cardiomyopathy	17/522	112/7206	0.00291190302596
ko04022	cGMP-PKG signaling pathway	28/522	216/7206	0.00294573530535
ko04110	Cell cycle	2/522	145/7206	0.00295628068175
ko03013	RNA transport	3/522	166/7206	0.00344010602608
ko05164	Influenza A	3/522	167/7206	0.0035033616863
ko04141	Protein processing in endoplasmic reticulum	4/522	184/7206	0.00366290456537
ko04925	Aldosterone synthesis and secretion	16/522	105/7206	0.00377804732947
ko05169	Epstein-Barr virus infection	5/522	206/7206	0.00383851554174
ko00230	Purine metabolism	25/522	194/7206	0.00447961811823
ko04218	Cellular senescence	4/522	177/7206	0.00508173709766
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/522	182/7206	0.00524770234135
ko04630	Jak-STAT signaling pathway	2/522	132/7206	0.00586202505257
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/522	79/7206	0.00664283383631
ko04144	Endocytosis	38/522	342/7206	0.00725265509987
ko05145	Toxoplasmosis	2/522	126/7206	0.00831669646692
ko04070	Phosphatidylinositol signaling system	16/522	112/7206	0.00854982433744
ko00562	Inositol phosphate metabolism	13/522	89/7206	0.0124626588687
ko04550	Signaling pathways regulating pluripotency of stem cells	4/522	165/7206	0.0137530583563
ko04930	Type II diabetes mellitus	9/522	54/7206	0.014524519841
ko04972	Pancreatic secretion	15/522	111/7206	0.015766510012
ko04915	Estrogen signaling pathway	17/522	131/7206	0.0163110844664
ko04621	NOD-like receptor signaling pathway	4/522	157/7206	0.0183311292923
ko04146	Peroxisome	1/522	89/7206	0.0208310911607
ko05034	Alcoholism	27/522	238/7206	0.0209598767078
ko05215	Prostate cancer	2/522	111/7206	0.0242858700008
ko05418	Fluid shear stress and atherosclerosis	5/522	173/7206	0.0244642276719
ko04670	Leukocyte transendothelial migration	4/522	151/7206	0.0249476264488
ko05322	Systemic lupus erythematosus	4/522	151/7206	0.0249476264488
ko04062	Chemokine signaling pathway	23/522	201/7206	0.0263628699926
ko05231	Choline metabolism in cancer	17/522	134/7206	0.0263687107065
ko04971	Gastric acid secretion	13/522	98/7206	0.0290969989965
ko04138	Autophagy - yeast	1/522	81/7206	0.0292871986388
ko05131	Shigellosis	1/522	82/7206	0.0295393190914
ko03018	RNA degradation	1/522	84/7206	0.030508889175
ko04510	Focal adhesion	9/522	240/7206	0.0308432615255
ko04140	Autophagy - animal	5/522	164/7206	0.0322096870724
ko05410	Hypertrophic cardiomyopathy (HCM)	13/522	100/7206	0.0322723083993
ko04966	Collecting duct acid secretion	5/522	26/7206	0.0361701979133
ko05166	HTLV-I infection	12/522	292/7206	0.0370250404397
ko04514	Cell adhesion molecules (CAMs)	16/522	130/7206	0.0377223584624
ko04310	Wnt signaling pathway	6/522	181/7206	0.0404723657754
ko05168	Herpes simplex infection	6/522	182/7206	0.0407878922968
ko01524	Platinum drug resistance	1/522	76/7206	0.0425416718076
ko04151	PI3K-Akt signaling pathway	18/522	390/7206	0.0437196310385
ko04120	Ubiquitin mediated proteolysis	4/522	138/7206	0.0454651937053
ko04064	NF-kappa B signaling pathway	2/522	96/7206	0.0463274346339
ko04666	Fc gamma R-mediated phagocytosis	15/522	122/7206	0.0493136369676