ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 23/225 38/7206 7.84251183077e-26 ko04110 Cell cycle 27/225 145/7206 2.98728855296e-14 ko03410 Base excision repair 12/225 38/7206 8.4733505182e-10 ko03430 Mismatch repair 9/225 22/7206 8.40350746476e-09 ko03420 Nucleotide excision repair 12/225 46/7206 9.75934694827e-09 ko04111 Cell cycle - yeast 15/225 90/7206 9.39213153623e-08 ko00240 Pyrimidine metabolism 16/225 110/7206 2.46711693051e-07 ko03460 Fanconi anemia pathway 10/225 51/7206 2.99779016105e-06 ko05222 Small cell lung cancer 13/225 89/7206 3.25637434578e-06 ko04080 Neuroactive ligand-receptor interaction 1/225 423/7206 3.31094482754e-05 ko04330 Notch signaling pathway 9/225 62/7206 0.000115364727585 ko04218 Cellular senescence 16/225 177/7206 0.000121262286654 ko05200 Pathways in cancer 31/225 492/7206 0.000139377608555 ko04113 Meiosis - yeast 9/225 70/7206 0.000297800592457 ko00670 One carbon pool by folate 5/225 20/7206 0.000299795749123 ko05224 Breast cancer 15/225 174/7206 0.000332786409895 ko01522 Endocrine resistance 12/225 124/7206 0.000464991505573 ko00230 Purine metabolism 15/225 194/7206 0.00104525755578 ko05217 Basal cell carcinoma 8/225 68/7206 0.00117299168924 ko03440 Homologous recombination 6/225 41/7206 0.00156034189917 ko04340 Hedgehog signaling pathway 7/225 58/7206 0.00204319766207 ko05206 MicroRNAs in cancer 13/225 177/7206 0.00350601006263 ko05220 Chronic myeloid leukemia 8/225 85/7206 0.00485608719095 ko05166 HTLV-I infection 18/225 292/7206 0.00522498218299 ko03040 Spliceosome 11/225 145/7206 0.00553640737727 ko05215 Prostate cancer 9/225 111/7206 0.00768151755673 ko05130 Pathogenic Escherichia coli infection 7/225 77/7206 0.0099284239958 ko05214 Glioma 7/225 79/7206 0.0113592458352 ko01523 Antifolate resistance 4/225 30/7206 0.0134073635182 ko04022 cGMP-PKG signaling pathway 1/225 216/7206 0.0153134709561 ko05219 Bladder cancer 5/225 48/7206 0.016317567033 ko05218 Melanoma 7/225 85/7206 0.0165446943183 ko04020 Calcium signaling pathway 2/225 265/7206 0.0178940075696 ko04261 Adrenergic signaling in cardiomyocytes 1/225 205/7206 0.0223512534557 ko03013 RNA transport 10/225 166/7206 0.0395406884739 ko05212 Pancreatic cancer 6/225 83/7206 0.0446500961458 ko04723 Retrograde endocannabinoid signaling 1/225 175/7206 0.0454216466601