ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 33/324 79/7206 2.04789739805e-24 ko04950 Maturity onset diabetes of the young 13/324 29/7206 8.56926927127e-11 ko04974 Protein digestion and absorption 22/324 96/7206 1.46130654252e-10 ko04975 Fat digestion and absorption 13/324 35/7206 1.45850839945e-09 ko00260 Glycine, serine and threonine metabolism 14/324 48/7206 1.25720360116e-08 ko04977 Vitamin digestion and absorption 9/324 22/7206 1.99244832533e-07 ko04976 Bile secretion 16/324 80/7206 3.77873050918e-07 ko05150 Staphylococcus aureus infection 10/324 36/7206 2.62893860754e-06 ko01200 Carbon metabolism 19/324 128/7206 3.74397163842e-06 ko04978 Mineral absorption 10/324 40/7206 7.46489303353e-06 ko01230 Biosynthesis of amino acids 14/324 85/7206 2.18274283111e-05 ko00983 Drug metabolism - other enzymes 9/324 42/7206 8.04274166806e-05 ko04614 Renin-angiotensin system 6/324 18/7206 9.25011026058e-05 ko03320 PPAR signaling pathway 11/324 69/7206 0.000224902493425 ko04964 Proximal tubule bicarbonate reclamation 7/324 29/7206 0.000230679425956 ko00980 Metabolism of xenobiotics by cytochrome P450 8/324 40/7206 0.000333517013225 ko04260 Cardiac muscle contraction 13/324 98/7206 0.000408701677282 ko04973 Carbohydrate digestion and absorption 8/324 42/7206 0.000473252795064 ko00480 Glutathione metabolism 9/324 55/7206 0.000685105945187 ko00040 Pentose and glucuronate interconversions 6/324 26/7206 0.000845549838631 ko00270 Cysteine and methionine metabolism 8/324 47/7206 0.0010367168332 ko05204 Chemical carcinogenesis 8/324 48/7206 0.00119638026511 ko05166 HTLV-I infection 3/324 292/7206 0.00128598176115 ko00630 Glyoxylate and dicarboxylate metabolism 7/324 38/7206 0.00131676335889 ko00010 Glycolysis / Gluconeogenesis 10/324 74/7206 0.00162672293769 ko05169 Epstein-Barr virus infection 1/324 206/7206 0.00164741345247 ko04146 Peroxisome 11/324 89/7206 0.00202166371783 ko00140 Steroid hormone biosynthesis 7/324 41/7206 0.00208963746756 ko05034 Alcoholism 2/324 238/7206 0.00215160217447 ko00830 Retinol metabolism 7/324 42/7206 0.00241291440207 ko00591 Linoleic acid metabolism 5/324 22/7206 0.0024917923253 ko04360 Axon guidance 2/324 233/7206 0.00318151288179 ko04141 Protein processing in endoplasmic reticulum 1/324 184/7206 0.00336540375858 ko04390 Hippo signaling pathway 1/324 188/7206 0.00348703230744 ko04217 Necroptosis 1/324 178/7206 0.00500319715842 ko04310 Wnt signaling pathway 1/324 181/7206 0.00521735865621 ko00330 Arginine and proline metabolism 8/324 61/7206 0.00562927882828 ko00982 Drug metabolism - cytochrome P450 6/324 37/7206 0.0056320866514 ko00710 Carbon fixation in photosynthetic organisms 5/324 27/7206 0.00635372457204 ko04920 Adipocytokine signaling pathway 10/324 89/7206 0.00635983080018 ko00250 Alanine, aspartate and glutamate metabolism 6/324 38/7206 0.00644120976867 ko03013 RNA transport 1/324 166/7206 0.00710937594754 ko00590 Arachidonic acid metabolism 7/324 52/7206 0.00815667830374 ko04512 ECM-receptor interaction 9/324 79/7206 0.00863647249613 ko04062 Chemokine signaling pathway 2/324 201/7206 0.00884210694233 ko04931 Insulin resistance 13/324 137/7206 0.0101749994211 ko05410 Hypertrophic cardiomyopathy (HCM) 10/324 100/7206 0.0140455509936 ko04922 Glucagon signaling pathway 12/324 128/7206 0.0148724175466 ko00053 Ascorbate and aldarate metabolism 4/324 22/7206 0.0154392832318 ko00620 Pyruvate metabolism 6/324 46/7206 0.0161970853657 ko00680 Methane metabolism 5/324 34/7206 0.0169536621942 ko00472 D-Arginine and D-ornithine metabolism 2/324 5/7206 0.0184143026544 ko00232 Caffeine metabolism 2/324 5/7206 0.0184143026544 ko00311 Penicillin and cephalosporin biosynthesis 2/324 5/7206 0.0184143026544 ko00020 Citrate cycle (TCA cycle) 5/324 35/7206 0.0190726061515 ko00220 Arginine biosynthesis 4/324 24/7206 0.0209052548764 ko04144 Endocytosis 7/324 342/7206 0.0222129863265 ko00770 Pantothenate and CoA biosynthesis 3/324 14/7206 0.0226600121741 ko05200 Pathways in cancer 12/324 492/7206 0.0233149367982 ko05161 Hepatitis B 2/324 173/7206 0.024818923184 ko05206 MicroRNAs in cancer 2/324 177/7206 0.0252811341219 ko04218 Cellular senescence 2/324 177/7206 0.0252811341219 ko02010 ABC transporters 5/324 39/7206 0.0292595923116 ko04630 Jak-STAT signaling pathway 1/324 132/7206 0.0313345151325 ko04380 Osteoclast differentiation 1/324 134/7206 0.0318688456189 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/324 135/7206 0.0322268838392 ko05020 Prion diseases 5/324 40/7206 0.0322527343146 ko04972 Pancreatic secretion 10/324 111/7206 0.0330150351415 ko04930 Type II diabetes mellitus 6/324 54/7206 0.0331812106916 ko04152 AMPK signaling pathway 13/324 161/7206 0.0338419542464 ko00051 Fructose and mannose metabolism 5/324 42/7206 0.0387948284221 ko05162 Measles 1/324 120/7206 0.0445581623302 ko04666 Fc gamma R-mediated phagocytosis 1/324 122/7206 0.0447995134553 ko04660 T cell receptor signaling pathway 1/324 124/7206 0.0453709035595 ko04060 Cytokine-cytokine receptor interaction 3/324 191/7206 0.0493223457688