ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	61/947	152/7206	4.03914452849e-17
ko04713	Circadian entrainment	56/947	136/7206	2.08836187217e-16
ko04080	Neuroactive ligand-receptor interaction	117/947	423/7206	2.09111061679e-16
ko04020	Calcium signaling pathway	81/947	265/7206	3.39258616714e-14
ko04921	Oxytocin signaling pathway	64/947	209/7206	2.0357845156e-11
ko04720	Long-term potentiation	39/947	99/7206	4.25379737431e-11
ko05032	Morphine addiction	39/947	110/7206	1.657120661e-09
ko04728	Dopaminergic synapse	55/947	185/7206	1.69414404488e-09
ko05031	Amphetamine addiction	34/947	91/7206	3.91836931204e-09
ko05033	Nicotine addiction	25/947	56/7206	6.61744516657e-09
ko04726	Serotonergic synapse	43/947	137/7206	2.04977763757e-08
ko04727	GABAergic synapse	37/947	110/7206	2.22656214356e-08
ko04925	Aldosterone synthesis and secretion	35/947	105/7206	6.93603935511e-08
ko04024	cAMP signaling pathway	69/947	279/7206	9.6779534411e-08
ko04970	Salivary secretion	32/947	95/7206	1.92293026677e-07
ko04730	Long-term depression	28/947	78/7206	2.49124974984e-07
ko04022	cGMP-PKG signaling pathway	56/947	216/7206	3.13186315408e-07
ko04723	Retrograde endocannabinoid signaling	48/947	175/7206	3.31287037191e-07
ko04725	Cholinergic synapse	45/947	160/7206	3.43038891176e-07
ko03010	Ribosome	1/947	129/7206	4.66275933022e-07
ko03040	Spliceosome	2/947	145/7206	6.05632818627e-07
ko04070	Phosphatidylinositol signaling system	34/947	112/7206	1.40864330109e-06
ko04922	Glucagon signaling pathway	37/947	128/7206	1.92091234996e-06
ko04911	Insulin secretion	34/947	117/7206	4.98389887634e-06
ko04745	Phototransduction - fly	16/947	38/7206	9.15019858404e-06
ko04971	Gastric acid secretion	29/947	98/7206	1.42744034315e-05
ko04514	Cell adhesion molecules (CAMs)	35/947	130/7206	1.99122522962e-05
ko04261	Adrenergic signaling in cardiomyocytes	49/947	205/7206	2.08879454327e-05
ko04750	Inflammatory mediator regulation of TRP channels	33/947	122/7206	3.352061849e-05
ko03013	RNA transport	6/947	166/7206	3.90884035508e-05
ko04371	Apelin signaling pathway	43/947	177/7206	4.05982023827e-05
ko04710	Circadian rhythm	16/947	43/7206	5.73906055819e-05
ko04072	Phospholipase D signaling pathway	46/947	197/7206	6.46916333848e-05
ko04014	Ras signaling pathway	60/947	279/7206	8.7489629122e-05
ko04110	Cell cycle	5/947	145/7206	9.79414641341e-05
ko05203	Viral carcinogenesis	18/947	277/7206	0.00038429927846
ko04540	Gap junction	31/947	128/7206	0.000522346694882
ko05322	Systemic lupus erythematosus	7/947	151/7206	0.000875117908758
ko04626	Plant-pathogen interaction	8/947	18/7206	0.00111680236267
ko04721	Synaptic vesicle cycle	21/947	80/7206	0.00134147168204
ko05014	Amyotrophic lateral sclerosis (ALS)	20/947	74/7206	0.00138334604065
ko04924	Renin secretion	22/947	86/7206	0.00182741613665
ko04742	Taste transduction	17/947	61/7206	0.00185781265898
ko04010	MAPK signaling pathway	61/947	321/7206	0.00227923391074
ko04270	Vascular smooth muscle contraction	34/947	154/7206	0.00229980043247
ko04114	Oocyte meiosis	31/947	139/7206	0.00317229130677
ko04740	Olfactory transduction	20/947	80/7206	0.00392370174282
ko04360	Axon guidance	46/947	233/7206	0.00404912614905
ko05230	Central carbon metabolism in cancer	20/947	81/7206	0.00429148328884
ko05214	Glioma	19/947	79/7206	0.00689383440837
ko05110	Vibrio cholerae infection	16/947	63/7206	0.00763105063087
ko00010	Glycolysis / Gluconeogenesis	18/947	74/7206	0.00834020460205
ko04015	Rap1 signaling pathway	52/947	278/7206	0.00834446762844
ko05169	Epstein-Barr virus infection	15/947	206/7206	0.00881170779363
ko04213	Longevity regulating pathway - multiple species	20/947	86/7206	0.00929197691697
ko04141	Protein processing in endoplasmic reticulum	13/947	184/7206	0.0107932579042
ko00240	Pyrimidine metabolism	6/947	110/7206	0.0146435393316
ko04966	Collecting duct acid secretion	8/947	26/7206	0.0152503304158
ko00562	Inositol phosphate metabolism	20/947	89/7206	0.0163678730127
ko00051	Fructose and mannose metabolism	11/947	42/7206	0.0197361197759
ko05010	Alzheimer's disease	38/947	202/7206	0.0197720118321
ko04066	HIF-1 signaling pathway	25/947	123/7206	0.0218742177442
ko04260	Cardiac muscle contraction	21/947	98/7206	0.0225050850272
ko04972	Pancreatic secretion	23/947	111/7206	0.0228373842225
ko04930	Type II diabetes mellitus	13/947	54/7206	0.0246346960497
ko05168	Herpes simplex infection	14/947	182/7206	0.0258728583262
ko04915	Estrogen signaling pathway	26/947	131/7206	0.0263689185788
ko04923	Regulation of lipolysis in adipocytes	17/947	77/7206	0.0264908471319
ko04137	Mitophagy - animal	18/947	82/7206	0.0304363474327
ko00362	Benzoate degradation	3/947	6/7206	0.0332676712918
ko05030	Cocaine addiction	16/947	73/7206	0.0349566532226
ko00680	Methane metabolism	9/947	34/7206	0.0359895120439
ko04657	IL-17 signaling pathway	5/947	87/7206	0.0374544123092
ko05130	Pathogenic Escherichia coli infection	4/947	77/7206	0.039991343028
ko03050	Proteasome	2/947	54/7206	0.0406614614349
ko04912	GnRH signaling pathway	24/947	122/7206	0.0412982259316
ko00520	Amino sugar and nucleotide sugar metabolism	2/947	55/7206	0.0417192232272
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/947	79/7206	0.0419778454456
ko04916	Melanogenesis	27/947	142/7206	0.0439430913004
ko00620	Pyruvate metabolism	11/947	46/7206	0.0447214421083
ko05414	Dilated cardiomyopathy	22/947	112/7206	0.0476554751062