ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	65/500	423/7206	5.85539699147e-10
ko04020	Calcium signaling pathway	46/500	265/7206	3.96215109047e-09
ko04724	Glutamatergic synapse	31/500	152/7206	3.46973564821e-08
ko04720	Long-term potentiation	24/500	99/7206	4.02158432253e-08
ko04070	Phosphatidylinositol signaling system	25/500	112/7206	1.20591706987e-07
ko04925	Aldosterone synthesis and secretion	24/500	105/7206	1.34433303032e-07
ko04713	Circadian entrainment	27/500	136/7206	4.78190756417e-07
ko05031	Amphetamine addiction	21/500	91/7206	6.94992018412e-07
ko04911	Insulin secretion	22/500	117/7206	1.38778215196e-05
ko04745	Phototransduction - fly	11/500	38/7206	3.46054782435e-05
ko04921	Oxytocin signaling pathway	31/500	209/7206	4.468954105e-05
ko04970	Salivary secretion	18/500	95/7206	7.53039499753e-05
ko04750	Inflammatory mediator regulation of TRP channels	21/500	122/7206	8.4830956698e-05
ko04742	Taste transduction	13/500	61/7206	0.000221513452595
ko04924	Renin secretion	16/500	86/7206	0.000233585440837
ko04730	Long-term depression	15/500	78/7206	0.000249427296673
ko04024	cAMP signaling pathway	36/500	279/7206	0.000257334282911
ko04922	Glucagon signaling pathway	21/500	128/7206	0.000264429076442
ko04022	cGMP-PKG signaling pathway	30/500	216/7206	0.000310621982216
ko04971	Gastric acid secretion	17/500	98/7206	0.000360016843267
ko05033	Nicotine addiction	12/500	56/7206	0.000364504980846
ko05322	Systemic lupus erythematosus	1/500	151/7206	0.000481903104275
ko04710	Circadian rhythm	10/500	43/7206	0.000562759769584
ko04728	Dopaminergic synapse	26/500	185/7206	0.000565284501654
ko04626	Plant-pathogen interaction	6/500	18/7206	0.000978352129421
ko05014	Amyotrophic lateral sclerosis (ALS)	13/500	74/7206	0.00154007409574
ko04727	GABAergic synapse	17/500	110/7206	0.00174460797628
ko04725	Cholinergic synapse	22/500	160/7206	0.00225239813443
ko03010	Ribosome	1/500	129/7206	0.00228371252809
ko04261	Adrenergic signaling in cardiomyocytes	26/500	205/7206	0.00293488945111
ko04726	Serotonergic synapse	19/500	137/7206	0.00330645959426
ko04723	Retrograde endocannabinoid signaling	23/500	175/7206	0.00358927099345
ko04114	Oocyte meiosis	19/500	139/7206	0.00373642158846
ko05032	Morphine addiction	16/500	110/7206	0.00394285492987
ko03040	Spliceosome	2/500	145/7206	0.00423283889391
ko04960	Aldosterone-regulated sodium reabsorption	8/500	41/7206	0.00632346971151
ko05203	Viral carcinogenesis	9/500	277/7206	0.0108606462791
ko05214	Glioma	12/500	79/7206	0.0111077760079
ko04930	Type II diabetes mellitus	9/500	54/7206	0.0111610581253
ko04740	Olfactory transduction	12/500	80/7206	0.0116945623719
ko05230	Central carbon metabolism in cancer	12/500	81/7206	0.012363066836
ko04137	Mitophagy - animal	12/500	82/7206	0.0131155113147
ko04270	Vascular smooth muscle contraction	19/500	154/7206	0.014619949399
ko04144	Endocytosis	13/500	342/7206	0.0161880067096
ko04540	Gap junction	16/500	128/7206	0.020554205491
ko04012	ErbB signaling pathway	14/500	109/7206	0.0214415991938
ko04915	Estrogen signaling pathway	16/500	131/7206	0.0231252882356
ko00350	Tyrosine metabolism	6/500	33/7206	0.024083551995
ko04721	Synaptic vesicle cycle	11/500	80/7206	0.0245761605219
ko05168	Herpes simplex infection	5/500	182/7206	0.0250041620334
ko04138	Autophagy - yeast	11/500	81/7206	0.0262460477121
ko00680	Methane metabolism	6/500	34/7206	0.0275897053542
ko04966	Collecting duct acid secretion	5/500	26/7206	0.0307699669915
ko04972	Pancreatic secretion	14/500	111/7206	0.035046689758
ko00010	Glycolysis / Gluconeogenesis	10/500	74/7206	0.0355418513685
ko05231	Choline metabolism in cancer	16/500	134/7206	0.0366001429025
ko00620	Pyruvate metabolism	7/500	46/7206	0.0376106485729
ko00561	Glycerolipid metabolism	9/500	63/7206	0.0392408718709
ko05202	Transcriptional misregulation in cancer	6/500	188/7206	0.0404744839805
ko04512	ECM-receptor interaction	1/500	79/7206	0.0427172308343
ko03013	RNA transport	5/500	166/7206	0.0433355199806
ko04916	Melanogenesis	16/500	142/7206	0.045577957032
ko04110	Cell cycle	4/500	145/7206	0.045906228422
ko04964	Proximal tubule bicarbonate reclamation	5/500	29/7206	0.0468887626719
ko04350	TGF-beta signaling pathway	2/500	103/7206	0.0475641910255
ko04918	Thyroid hormone synthesis	11/500	86/7206	0.0495297869238
ko05169	Epstein-Barr virus infection	7/500	206/7206	0.0495542760211