ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	175/970	423/7206	2.22387919606e-49
ko05033	Nicotine addiction	46/970	56/7206	3.12029783489e-31
ko04724	Glutamatergic synapse	78/970	152/7206	1.42796343807e-29
ko04713	Circadian entrainment	66/970	136/7206	2.23874509744e-23
ko05032	Morphine addiction	55/970	110/7206	1.9452797574e-20
ko04728	Dopaminergic synapse	73/970	185/7206	3.62941234302e-19
ko04727	GABAergic synapse	53/970	110/7206	8.33933928685e-19
ko04024	cAMP signaling pathway	90/970	279/7206	1.77123167912e-16
ko04723	Retrograde endocannabinoid signaling	66/970	175/7206	3.01228524812e-16
ko04725	Cholinergic synapse	62/970	160/7206	5.4669520321e-16
ko04744	Phototransduction	26/970	36/7206	1.11243357867e-15
ko04020	Calcium signaling pathway	84/970	265/7206	4.64996668823e-15
ko04726	Serotonergic synapse	53/970	137/7206	8.35219073864e-14
ko04721	Synaptic vesicle cycle	37/970	80/7206	8.2646464539e-13
ko04742	Taste transduction	31/970	61/7206	2.63100528143e-12
ko04921	Oxytocin signaling pathway	66/970	209/7206	6.76629735616e-12
ko04911	Insulin secretion	44/970	117/7206	3.4428637916e-11
ko05031	Amphetamine addiction	37/970	91/7206	9.1949984613e-11
ko04740	Olfactory transduction	34/970	80/7206	1.27079995198e-10
ko04720	Long-term potentiation	36/970	99/7206	6.19808384282e-09
ko04970	Salivary secretion	35/970	95/7206	6.78119283215e-09
ko05203	Viral carcinogenesis	9/970	277/7206	8.06344528442e-09
ko03040	Spliceosome	1/970	145/7206	2.30619098556e-08
ko04261	Adrenergic signaling in cardiomyocytes	57/970	205/7206	3.40204474785e-08
ko04925	Aldosterone synthesis and secretion	36/970	105/7206	3.69100960999e-08
ko05030	Cocaine addiction	28/970	73/7206	8.14285172263e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	28/970	74/7206	1.14458056774e-07
ko04971	Gastric acid secretion	33/970	98/7206	2.22255276474e-07
ko05164	Influenza A	4/970	167/7206	9.04519675701e-07
ko05168	Herpes simplex infection	6/970	182/7206	4.50563737859e-06
ko04514	Cell adhesion molecules (CAMs)	37/970	130/7206	5.78950581056e-06
ko04060	Cytokine-cytokine receptor interaction	7/970	191/7206	7.54265340715e-06
ko05322	Systemic lupus erythematosus	4/970	151/7206	9.17293197331e-06
ko04745	Phototransduction - fly	16/970	38/7206	1.2504841392e-05
ko05169	Epstein-Barr virus infection	9/970	206/7206	1.77191673048e-05
ko05166	HTLV-I infection	17/970	292/7206	2.35754577716e-05
ko04120	Ubiquitin mediated proteolysis	4/970	138/7206	3.94753819688e-05
ko05162	Measles	3/970	120/7206	6.44709383349e-05
ko04730	Long-term depression	24/970	78/7206	6.57125188244e-05
ko04621	NOD-like receptor signaling pathway	6/970	157/7206	7.62870438887e-05
ko04976	Bile secretion	24/970	80/7206	9.3424671074e-05
ko04978	Mineral absorption	15/970	40/7206	0.000116245258902
ko04972	Pancreatic secretion	30/970	111/7206	0.000117470842584
ko03013	RNA transport	7/970	166/7206	0.000118171878716
ko05161	Hepatitis B	8/970	173/7206	0.000170628230314
ko05205	Proteoglycans in cancer	17/970	271/7206	0.00017811232467
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/970	79/7206	0.000205134756135
ko04010	MAPK signaling pathway	66/970	321/7206	0.000299040218844
ko04110	Cell cycle	6/970	145/7206	0.000302235666651
ko04612	Antigen processing and presentation	1/970	77/7206	0.000307388901038
ko04022	cGMP-PKG signaling pathway	48/970	216/7206	0.000349227704093
ko04260	Cardiac muscle contraction	26/970	98/7206	0.000482002240489
ko04750	Inflammatory mediator regulation of TRP channels	30/970	122/7206	0.000732891540842
ko04924	Renin secretion	23/970	86/7206	0.00113304825445
ko04150	mTOR signaling pathway	11/970	184/7206	0.00140912724904
ko04141	Protein processing in endoplasmic reticulum	11/970	184/7206	0.00140912724904
ko03008	Ribosome biogenesis in eukaryotes	2/970	79/7206	0.00144976332969
ko04070	Phosphatidylinositol signaling system	27/970	112/7206	0.00192921270201
ko04330	Notch signaling pathway	1/970	62/7206	0.0022959569249
ko04540	Gap junction	30/970	128/7206	0.00231777142311
ko04360	Axon guidance	48/970	233/7206	0.00231990807158
ko05215	Prostate cancer	5/970	111/7206	0.0029577352644
ko05200	Pathways in cancer	45/970	492/7206	0.00317241216972
ko05140	Leishmaniasis	2/970	75/7206	0.00317581151004
ko04964	Proximal tubule bicarbonate reclamation	10/970	29/7206	0.00331159996867
ko04140	Autophagy - animal	10/970	164/7206	0.00355887378148
ko04064	NF-kappa B signaling pathway	4/970	96/7206	0.00394467492316
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/970	182/7206	0.00406239025104
ko04630	Jak-STAT signaling pathway	7/970	132/7206	0.00418809566568
ko00480	Glutathione metabolism	1/970	55/7206	0.00507888098784
ko04014	Ras signaling pathway	54/970	279/7206	0.00532166406013
ko04626	Plant-pathogen interaction	7/970	18/7206	0.00645953235944
ko05206	MicroRNAs in cancer	12/970	177/7206	0.00704709417654
ko04610	Complement and coagulation cascades	3/970	79/7206	0.00734521402262
ko04550	Signaling pathways regulating pluripotency of stem cells	11/970	165/7206	0.00761130073737
ko04510	Focal adhesion	19/970	240/7206	0.00912134774725
ko04657	IL-17 signaling pathway	4/970	87/7206	0.0108066102011
ko04072	Phospholipase D signaling pathway	39/970	197/7206	0.010908219349
ko05414	Dilated cardiomyopathy	25/970	112/7206	0.0110732424058
ko00330	Arginine and proline metabolism	2/970	61/7206	0.013520536702
ko00310	Lysine degradation	3/970	73/7206	0.0147397534277
ko03018	RNA degradation	4/970	84/7206	0.0150292325498
ko05220	Chronic myeloid leukemia	4/970	85/7206	0.0152479341377
ko00620	Pyruvate metabolism	1/970	46/7206	0.0165361310016
ko03420	Nucleotide excision repair	1/970	46/7206	0.0165361310016
ko05410	Hypertrophic cardiomyopathy (HCM)	22/970	100/7206	0.0173308308709
ko04915	Estrogen signaling pathway	27/970	131/7206	0.0197790353402
ko04210	Apoptosis	14/970	180/7206	0.020211065566
ko04142	Lysosome	11/970	151/7206	0.0217724324952
ko03022	Basal transcription factors	1/970	44/7206	0.0246005304913
ko05144	Malaria	1/970	45/7206	0.0252872807738
ko00071	Fatty acid degradation	1/970	45/7206	0.0252872807738
ko04218	Cellular senescence	14/970	177/7206	0.0256350833921
ko04146	Peroxisome	5/970	89/7206	0.0275675224215
ko05416	Viral myocarditis	2/970	55/7206	0.0279033762939
ko00280	Valine, leucine and isoleucine degradation	2/970	54/7206	0.0279237065246
ko05321	Inflammatory bowel disease (IBD)	2/970	56/7206	0.0283254622849
ko05130	Pathogenic Escherichia coli infection	4/970	77/7206	0.0285774311957
ko05217	Basal cell carcinoma	3/970	68/7206	0.0298475245888
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/970	14/7206	0.0307158916408
ko05211	Renal cell carcinoma	6/970	96/7206	0.0346136182125
ko04658	Th1 and Th2 cell differentiation	6/970	96/7206	0.0346136182125
ko05145	Toxoplasmosis	9/970	126/7206	0.0346264310341
ko05020	Prion diseases	1/970	40/7206	0.0359982357986
ko04115	p53 signaling pathway	4/970	74/7206	0.0392209434193
ko00590	Arachidonic acid metabolism	2/970	52/7206	0.0398969267425
ko04350	TGF-beta signaling pathway	7/970	103/7206	0.0421796664369
ko05016	Huntington's disease	19/970	215/7206	0.0424390213907