ko pathway ratio_in_study ratio_in_pop p_value ko04080 Neuroactive ligand-receptor interaction 51/343 423/7206 3.73940012017e-10 ko05033 Nicotine addiction 17/343 56/7206 4.00337309079e-10 ko05032 Morphine addiction 23/343 110/7206 1.21653462335e-09 ko04723 Retrograde endocannabinoid signaling 24/343 175/7206 2.37547962332e-06 ko04727 GABAergic synapse 18/343 110/7206 3.63502382808e-06 ko04024 cAMP signaling pathway 32/343 279/7206 3.7258191119e-06 ko04721 Synaptic vesicle cycle 15/343 80/7206 4.22988970906e-06 ko04725 Cholinergic synapse 22/343 160/7206 6.04710207216e-06 ko04724 Glutamatergic synapse 21/343 152/7206 9.15044560507e-06 ko04010 MAPK signaling pathway 32/343 321/7206 6.80542827816e-05 ko04921 Oxytocin signaling pathway 23/343 209/7206 0.000170821454694 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/343 14/7206 0.000332714631303 ko04911 Insulin secretion 15/343 117/7206 0.000404524229757 ko04020 Calcium signaling pathway 25/343 265/7206 0.000987897192918 ko04072 Phospholipase D signaling pathway 20/343 197/7206 0.00171296740179 ko04070 Phosphatidylinositol signaling system 13/343 112/7206 0.0024372751185 ko04713 Circadian entrainment 15/343 136/7206 0.00318496923379 ko04930 Type II diabetes mellitus 8/343 54/7206 0.00370899756559 ko04925 Aldosterone synthesis and secretion 12/343 105/7206 0.00401844745825 ko04071 Sphingolipid signaling pathway 16/343 162/7206 0.00464867130017 ko03013 RNA transport 1/343 166/7206 0.00488304476174 ko04726 Serotonergic synapse 14/343 137/7206 0.00663841270277 ko04728 Dopaminergic synapse 17/343 185/7206 0.00797012276787 ko04514 Cell adhesion molecules (CAMs) 13/343 130/7206 0.0103757641725 ko04360 Axon guidance 20/343 233/7206 0.0110055720257 ko04970 Salivary secretion 10/343 95/7206 0.0144831531759 ko04120 Ubiquitin mediated proteolysis 1/343 138/7206 0.0148085986647 ko04710 Circadian rhythm 6/343 43/7206 0.015299595958 ko04145 Phagosome 2/343 162/7206 0.0247088214124 ko04742 Taste transduction 7/343 61/7206 0.0249423757326 ko04744 Phototransduction 5/343 36/7206 0.0265740270493 ko00190 Oxidative phosphorylation 1/343 127/7206 0.0318759791934 ko01200 Carbon metabolism 1/343 128/7206 0.0322850871361 ko04144 Endocytosis 25/343 342/7206 0.0358116584169 ko04931 Insulin resistance 12/343 137/7206 0.0390388955612 ko05203 Viral carcinogenesis 6/343 277/7206 0.0420912753562 ko04014 Ras signaling pathway 21/343 279/7206 0.0426397036851 ko04261 Adrenergic signaling in cardiomyocytes 16/343 205/7206 0.0449602513155 ko05016 Huntington's disease 4/343 215/7206 0.0483629502739