ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	167/965	423/7206	4.84219956868e-44
ko04724	Glutamatergic synapse	77/965	152/7206	7.21654054363e-29
ko05033	Nicotine addiction	42/965	56/7206	8.5414711815e-26
ko05032	Morphine addiction	56/965	110/7206	2.17683227746e-21
ko04713	Circadian entrainment	63/965	136/7206	3.99499993725e-21
ko04727	GABAergic synapse	55/965	110/7206	1.51610771211e-20
ko04728	Dopaminergic synapse	70/965	185/7206	2.21998266467e-17
ko04744	Phototransduction	27/965	36/7206	5.41738081595e-17
ko04723	Retrograde endocannabinoid signaling	67/965	175/7206	5.45877294144e-17
ko04725	Cholinergic synapse	61/965	160/7206	1.81999365602e-15
ko04020	Calcium signaling pathway	82/965	265/7206	4.33551690976e-14
ko04740	Olfactory transduction	38/965	80/7206	1.17957555183e-13
ko04024	cAMP signaling pathway	83/965	279/7206	2.71555396819e-13
ko04726	Serotonergic synapse	52/965	137/7206	2.85778847404e-13
ko04742	Taste transduction	32/965	61/7206	3.19259087922e-13
ko04721	Synaptic vesicle cycle	36/965	80/7206	3.98655431416e-12
ko04921	Oxytocin signaling pathway	66/965	209/7206	5.95665870088e-12
ko04911	Insulin secretion	44/965	117/7206	2.88813283246e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/965	205/7206	1.98491538936e-10
ko04970	Salivary secretion	36/965	95/7206	1.46045669713e-09
ko05031	Amphetamine addiction	33/965	91/7206	2.53509616732e-08
ko05203	Viral carcinogenesis	10/965	277/7206	3.97964596533e-08
ko05164	Influenza A	3/965	167/7206	1.99463755346e-07
ko04720	Long-term potentiation	33/965	99/7206	2.57585100523e-07
ko03040	Spliceosome	2/965	145/7206	3.86547343282e-07
ko04971	Gastric acid secretion	32/965	98/7206	6.62253901628e-07
ko04120	Ubiquitin mediated proteolysis	2/965	138/7206	8.48526694732e-07
ko05168	Herpes simplex infection	5/965	182/7206	1.26795559197e-06
ko05322	Systemic lupus erythematosus	3/965	151/7206	1.38324296502e-06
ko04925	Aldosterone synthesis and secretion	33/965	105/7206	1.4311477042e-06
ko04260	Cardiac muscle contraction	31/965	98/7206	2.81884471046e-06
ko05030	Cocaine addiction	25/965	73/7206	4.19536316876e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/965	74/7206	5.54399573498e-06
ko03013	RNA transport	5/965	166/7206	7.88771418059e-06
ko05162	Measles	2/965	120/7206	9.33496176423e-06
ko04514	Cell adhesion molecules (CAMs)	36/965	130/7206	1.19513849529e-05
ko04972	Pancreatic secretion	32/965	111/7206	1.50550133828e-05
ko04022	cGMP-PKG signaling pathway	52/965	216/7206	1.57819054459e-05
ko04010	MAPK signaling pathway	70/965	321/7206	2.34080054982e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/965	79/7206	3.11991973564e-05
ko05166	HTLV-I infection	17/965	292/7206	3.19002965101e-05
ko04745	Phototransduction - fly	15/965	38/7206	5.46691188941e-05
ko05169	Epstein-Barr virus infection	10/965	206/7206	6.81730411904e-05
ko04621	NOD-like receptor signaling pathway	6/965	157/7206	7.65921581606e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/965	182/7206	9.12429889421e-05
ko04060	Cytokine-cytokine receptor interaction	9/965	191/7206	9.22868358296e-05
ko04978	Mineral absorption	15/965	40/7206	0.000109499076736
ko04974	Protein digestion and absorption	27/965	96/7206	0.000112901227599
ko04730	Long-term depression	23/965	78/7206	0.000158492051089
ko05205	Proteoglycans in cancer	17/965	271/7206	0.000178031600718
ko04964	Proximal tubule bicarbonate reclamation	12/965	29/7206	0.000179780931068
ko05161	Hepatitis B	8/965	173/7206	0.000247190189535
ko04110	Cell cycle	6/965	145/7206	0.00030120242603
ko03008	Ribosome biogenesis in eukaryotes	1/965	79/7206	0.000326239856064
ko04540	Gap junction	32/965	128/7206	0.000335853928274
ko04976	Bile secretion	23/965	80/7206	0.00034928994483
ko05414	Dilated cardiomyopathy	28/965	112/7206	0.00106128928573
ko04630	Jak-STAT signaling pathway	6/965	132/7206	0.00114078093177
ko05410	Hypertrophic cardiomyopathy (HCM)	25/965	100/7206	0.00159974718545
ko04150	mTOR signaling pathway	11/965	184/7206	0.00194179770858
ko04141	Protein processing in endoplasmic reticulum	11/965	184/7206	0.00194179770858
ko04924	Renin secretion	22/965	86/7206	0.0021035494676
ko04610	Complement and coagulation cascades	2/965	79/7206	0.00223862363459
ko04330	Notch signaling pathway	1/965	62/7206	0.00229775568917
ko05215	Prostate cancer	5/965	111/7206	0.00296222114538
ko05140	Leishmaniasis	2/965	75/7206	0.00314834478483
ko05220	Chronic myeloid leukemia	3/965	85/7206	0.00362994160864
ko04064	NF-kappa B signaling pathway	4/965	96/7206	0.00396574493585
ko04668	TNF signaling pathway	6/965	120/7206	0.00416269150727
ko00310	Lysine degradation	2/965	73/7206	0.00476332901982
ko04371	Apelin signaling pathway	37/965	177/7206	0.00493340801865
ko04142	Lysosome	9/965	151/7206	0.00508966858373
ko03018	RNA degradation	3/965	84/7206	0.00534302654178
ko04750	Inflammatory mediator regulation of TRP channels	27/965	122/7206	0.00693328663612
ko04014	Ras signaling pathway	53/965	279/7206	0.00699138710285
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/965	135/7206	0.00712013906677
ko04550	Signaling pathways regulating pluripotency of stem cells	11/965	165/7206	0.00761148697632
ko00280	Valine, leucine and isoleucine degradation	1/965	54/7206	0.0077185473292
ko05016	Huntington's disease	16/965	215/7206	0.00789825362647
ko00520	Amino sugar and nucleotide sugar metabolism	1/965	55/7206	0.00805264553293
ko04140	Autophagy - animal	11/965	164/7206	0.0101515721194
ko04657	IL-17 signaling pathway	4/965	87/7206	0.0108196678109
ko04218	Cellular senescence	13/965	177/7206	0.0137832068262
ko04214	Apoptosis - fly	3/965	72/7206	0.0147214364828
ko05211	Renal cell carcinoma	5/965	96/7206	0.0149080094493
ko03420	Nucleotide excision repair	1/965	46/7206	0.0166055025439
ko03022	Basal transcription factors	1/965	44/7206	0.0245704135666
ko00071	Fatty acid degradation	1/965	45/7206	0.0251387027651
ko04210	Apoptosis	14/965	180/7206	0.0259085171552
ko04620	Toll-like receptor signaling pathway	6/965	100/7206	0.0259313502338
ko04930	Type II diabetes mellitus	13/965	54/7206	0.0271570078853
ko04146	Peroxisome	5/965	89/7206	0.0275310992176
ko05321	Inflammatory bowel disease (IBD)	2/965	56/7206	0.0282181210298
ko04664	Fc epsilon RI signaling pathway	4/965	77/7206	0.0286519995805
ko05217	Basal cell carcinoma	3/965	68/7206	0.0296375288077
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/965	14/7206	0.0301005981449
ko04658	Th1 and Th2 cell differentiation	6/965	96/7206	0.0346910050277
ko00190	Oxidative phosphorylation	9/965	127/7206	0.0347358093834
ko00564	Glycerophospholipid metabolism	6/965	99/7206	0.035718300695
ko05020	Prion diseases	1/965	40/7206	0.0360924148891
ko04915	Estrogen signaling pathway	26/965	131/7206	0.037210806119
ko05133	Pertussis	5/965	87/7206	0.0377472745363
ko01524	Platinum drug resistance	4/965	76/7206	0.0400292780822
ko05012	Parkinson's disease	12/965	155/7206	0.0415639915295
ko04512	ECM-receptor interaction	17/965	79/7206	0.0442301448013
ko04660	T cell receptor signaling pathway	9/965	124/7206	0.0450826156348