ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/598	56/7206	4.72294655271e-22
ko04724	Glutamatergic synapse	54/598	152/7206	1.25817854862e-21
ko04721	Synaptic vesicle cycle	35/598	80/7206	9.3120380044e-18
ko04727	GABAergic synapse	40/598	110/7206	1.07114330732e-16
ko05032	Morphine addiction	39/598	110/7206	7.10764682413e-16
ko04728	Dopaminergic synapse	52/598	185/7206	7.66979856975e-16
ko04080	Neuroactive ligand-receptor interaction	86/598	423/7206	7.89592113039e-16
ko04723	Retrograde endocannabinoid signaling	49/598	175/7206	6.48318142326e-15
ko04713	Circadian entrainment	39/598	136/7206	1.82747708374e-12
ko04911	Insulin secretion	32/598	117/7206	7.18122410599e-10
ko04725	Cholinergic synapse	37/598	160/7206	5.60415980214e-09
ko04024	cAMP signaling pathway	53/598	279/7206	5.91933112021e-09
ko04744	Phototransduction	16/598	36/7206	6.31103702643e-09
ko04726	Serotonergic synapse	33/598	137/7206	1.30458678594e-08
ko04514	Cell adhesion molecules (CAMs)	31/598	130/7206	4.66123093089e-08
ko05030	Cocaine addiction	21/598	73/7206	2.48169654137e-07
ko05031	Amphetamine addiction	22/598	91/7206	3.3310189662e-06
ko04261	Adrenergic signaling in cardiomyocytes	36/598	205/7206	1.39239605685e-05
ko05203	Viral carcinogenesis	6/598	277/7206	1.97274514944e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/598	74/7206	2.36603165059e-05
ko04010	MAPK signaling pathway	49/598	321/7206	2.6491558411e-05
ko05322	Systemic lupus erythematosus	1/598	151/7206	6.50941913972e-05
ko04060	Cytokine-cytokine receptor interaction	3/598	191/7206	9.24010951257e-05
ko03040	Spliceosome	1/598	145/7206	9.26304358744e-05
ko05164	Influenza A	2/598	167/7206	9.72605516522e-05
ko04120	Ubiquitin mediated proteolysis	1/598	138/7206	0.000132500972264
ko04720	Long-term potentiation	20/598	99/7206	0.000144917689843
ko04970	Salivary secretion	19/598	95/7206	0.00024224997694
ko04742	Taste transduction	14/598	61/7206	0.000363172871442
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/598	14/7206	0.000535853653308
ko04730	Long-term depression	16/598	78/7206	0.000549299189509
ko05162	Measles	1/598	120/7206	0.000637316862096
ko04972	Pancreatic secretion	20/598	111/7206	0.000765751004389
ko04966	Collecting duct acid secretion	8/598	26/7206	0.00087207751265
ko05205	Proteoglycans in cancer	9/598	271/7206	0.00149357612252
ko04964	Proximal tubule bicarbonate reclamation	8/598	29/7206	0.00191787491428
ko04140	Autophagy - animal	4/598	164/7206	0.00365531203099
ko05168	Herpes simplex infection	5/598	182/7206	0.00379183274924
ko04621	NOD-like receptor signaling pathway	4/598	157/7206	0.00493757192093
ko04921	Oxytocin signaling pathway	29/598	209/7206	0.00498545714797
ko04976	Bile secretion	14/598	80/7206	0.00655475586285
ko04360	Axon guidance	31/598	233/7206	0.00760022800662
ko04022	cGMP-PKG signaling pathway	29/598	216/7206	0.00832282275609
ko04260	Cardiac muscle contraction	16/598	98/7206	0.00834373559873
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/598	182/7206	0.00929017520519
ko04141	Protein processing in endoplasmic reticulum	6/598	184/7206	0.00940365328657
ko03013	RNA transport	5/598	166/7206	0.00959610384734
ko05166	HTLV-I infection	13/598	292/7206	0.0124099865956
ko04211	Longevity regulating pathway	3/598	123/7206	0.0125000505902
ko03008	Ribosome biogenesis in eukaryotes	1/598	79/7206	0.0134436939613
ko04540	Gap junction	19/598	128/7206	0.0137327959224
ko04020	Calcium signaling pathway	33/598	265/7206	0.0167673292917
ko05161	Hepatitis B	6/598	173/7206	0.0168391485353
ko05110	Vibrio cholerae infection	11/598	63/7206	0.0177219978553
ko04612	Antigen processing and presentation	1/598	77/7206	0.0199408460876
ko05169	Epstein-Barr virus infection	8/598	206/7206	0.0199981808479
ko05215	Prostate cancer	3/598	111/7206	0.0240753479749
ko04217	Necroptosis	7/598	178/7206	0.0276247269663
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/598	59/7206	0.0279586666867
ko04214	Apoptosis - fly	1/598	72/7206	0.0289152319997
ko00512	Mucin type O-glycan biosynthesis	6/598	29/7206	0.029126662231
ko04611	Platelet activation	6/598	163/7206	0.0299351898679
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/598	15/7206	0.0306244745038
ko05034	Alcoholism	29/598	238/7206	0.0314191803418
ko04146	Peroxisome	2/598	89/7206	0.0322043732735
ko04072	Phospholipase D signaling pathway	25/598	197/7206	0.0346689994622
ko04014	Ras signaling pathway	33/598	279/7206	0.0349745475515
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/598	79/7206	0.0370907642185
ko04810	Regulation of actin cytoskeleton	13/598	264/7206	0.0406276831619
ko04978	Mineral absorption	7/598	40/7206	0.0440800601623
ko05220	Chronic myeloid leukemia	2/598	85/7206	0.0456106434005
ko04910	Insulin signaling pathway	7/598	172/7206	0.0483174431902