ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	151/922	423/7206	4.73385766761e-36
ko04724	Glutamatergic synapse	79/922	152/7206	5.10870466585e-32
ko05033	Nicotine addiction	45/922	56/7206	9.23539762754e-31
ko05032	Morphine addiction	64/922	110/7206	6.85084892393e-30
ko04727	GABAergic synapse	59/922	110/7206	4.53302854852e-25
ko04728	Dopaminergic synapse	74/922	185/7206	3.72403451521e-21
ko04723	Retrograde endocannabinoid signaling	71/922	175/7206	9.36319060314e-21
ko04713	Circadian entrainment	61/922	136/7206	1.24470092799e-20
ko04725	Cholinergic synapse	66/922	160/7206	8.00068604894e-20
ko04024	cAMP signaling pathway	86/922	279/7206	5.61056172135e-16
ko04721	Synaptic vesicle cycle	39/922	80/7206	4.02838554818e-15
ko04744	Phototransduction	25/922	36/7206	5.23765267436e-15
ko04921	Oxytocin signaling pathway	66/922	209/7206	7.10986435321e-13
ko04911	Insulin secretion	45/922	117/7206	1.37001518914e-12
ko04020	Calcium signaling pathway	74/922	265/7206	2.64044314955e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/922	205/7206	3.35040626608e-11
ko04726	Serotonergic synapse	47/922	137/7206	4.96357465025e-11
ko04742	Taste transduction	28/922	61/7206	1.94048352363e-10
ko05031	Amphetamine addiction	35/922	91/7206	4.42574347546e-10
ko04720	Long-term potentiation	34/922	99/7206	2.35168795436e-08
ko05030	Cocaine addiction	27/922	73/7206	1.15473535714e-07
ko04010	MAPK signaling pathway	73/922	321/7206	5.04808617925e-07
ko03040	Spliceosome	2/922	145/7206	9.21159354168e-07
ko05203	Viral carcinogenesis	12/922	277/7206	2.15563072559e-06
ko05322	Systemic lupus erythematosus	3/922	151/7206	3.18244209016e-06
ko04925	Aldosterone synthesis and secretion	31/922	105/7206	4.58553433392e-06
ko03013	RNA transport	5/922	166/7206	1.69173339871e-05
ko04072	Phospholipase D signaling pathway	47/922	197/7206	1.79136925726e-05
ko04022	cGMP-PKG signaling pathway	50/922	216/7206	1.84182817663e-05
ko04070	Phosphatidylinositol signaling system	31/922	112/7206	2.08011080555e-05
ko04060	Cytokine-cytokine receptor interaction	7/922	191/7206	2.2752247019e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/922	74/7206	2.85131268058e-05
ko04514	Cell adhesion molecules (CAMs)	34/922	130/7206	2.89925050272e-05
ko04970	Salivary secretion	27/922	95/7206	3.80285500154e-05
ko04110	Cell cycle	4/922	145/7206	4.17161007776e-05
ko04972	Pancreatic secretion	30/922	111/7206	4.28475794118e-05
ko05168	Herpes simplex infection	7/922	182/7206	6.47044522436e-05
ko04360	Axon guidance	51/922	233/7206	8.55931689899e-05
ko04260	Cardiac muscle contraction	27/922	98/7206	8.64975834025e-05
ko04971	Gastric acid secretion	27/922	98/7206	8.64975834025e-05
ko05164	Influenza A	7/922	167/7206	0.000238524852655
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/922	79/7206	0.000276111181079
ko03008	Ribosome biogenesis in eukaryotes	1/922	79/7206	0.000497369290271
ko04740	Olfactory transduction	22/922	80/7206	0.000524400126173
ko05205	Proteoglycans in cancer	17/922	271/7206	0.000556528728845
ko05169	Epstein-Barr virus infection	11/922	206/7206	0.000623512010058
ko04730	Long-term depression	21/922	78/7206	0.000852811960996
ko04014	Ras signaling pathway	55/922	279/7206	0.000920907916158
ko04141	Protein processing in endoplasmic reticulum	10/922	184/7206	0.00157003503392
ko04745	Phototransduction - fly	12/922	38/7206	0.00200566709713
ko04964	Proximal tubule bicarbonate reclamation	10/922	29/7206	0.00225876201071
ko04621	NOD-like receptor signaling pathway	8/922	157/7206	0.00226891886149
ko05414	Dilated cardiomyopathy	26/922	112/7206	0.00234732082256
ko04612	Antigen processing and presentation	2/922	77/7206	0.00317987146873
ko04915	Estrogen signaling pathway	29/922	131/7206	0.00326204100696
ko04610	Complement and coagulation cascades	2/922	79/7206	0.00329870169943
ko05140	Leishmaniasis	2/922	75/7206	0.00467563981961
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/922	14/7206	0.00520268664349
ko05215	Prostate cancer	5/922	111/7206	0.00592335476994
ko04930	Type II diabetes mellitus	14/922	54/7206	0.00722813671319
ko05161	Hepatitis B	11/922	173/7206	0.00778879053989
ko05162	Measles	6/922	120/7206	0.00811480621813
ko04924	Renin secretion	20/922	86/7206	0.00820463888547
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/922	59/7206	0.00904696100787
ko05410	Hypertrophic cardiomyopathy (HCM)	22/922	100/7206	0.00956106100879
ko04120	Ubiquitin mediated proteolysis	8/922	138/7206	0.0097371126287
ko03320	PPAR signaling pathway	2/922	69/7206	0.00987406454056
ko04510	Focal adhesion	18/922	240/7206	0.0104066917904
ko04350	TGF-beta signaling pathway	5/922	103/7206	0.0110653843465
ko00590	Arachidonic acid metabolism	1/922	52/7206	0.0114586920873
ko04966	Collecting duct acid secretion	8/922	26/7206	0.0130696515769
ko04750	Inflammatory mediator regulation of TRP channels	25/922	122/7206	0.0137510930284
ko05130	Pathogenic Escherichia coli infection	3/922	77/7206	0.0151377179023
ko04146	Peroxisome	4/922	89/7206	0.0154983077941
ko04976	Bile secretion	18/922	80/7206	0.0167019371389
ko04710	Circadian rhythm	11/922	43/7206	0.0196157049534
ko00330	Arginine and proline metabolism	2/922	61/7206	0.0198889319822
ko00240	Pyrimidine metabolism	6/922	110/7206	0.0201123622965
ko04064	NF-kappa B signaling pathway	5/922	96/7206	0.0206206769707
ko04657	IL-17 signaling pathway	4/922	87/7206	0.0220168235695
ko05133	Pertussis	4/922	87/7206	0.0220168235695
ko00562	Inositol phosphate metabolism	19/922	89/7206	0.0237054993733
ko00071	Fatty acid degradation	1/922	45/7206	0.0249670279045
ko03420	Nucleotide excision repair	1/922	46/7206	0.0250256837453
ko05231	Choline metabolism in cancer	26/922	134/7206	0.02602654959
ko05219	Bladder cancer	1/922	48/7206	0.0265324129442
ko05131	Shigellosis	4/922	82/7206	0.0293124217424
ko04630	Jak-STAT signaling pathway	9/922	132/7206	0.035219913039
ko00565	Ether lipid metabolism	1/922	42/7206	0.0366804721468
ko03022	Basal transcription factors	1/922	44/7206	0.0378037677193
ko04371	Apelin signaling pathway	32/922	177/7206	0.0396800648336
ko05166	HTLV-I infection	26/922	292/7206	0.0398612337001
ko00280	Valine, leucine and isoleucine degradation	2/922	54/7206	0.0405071735367
ko00480	Glutathione metabolism	2/922	55/7206	0.0407476868687
ko05321	Inflammatory bowel disease (IBD)	2/922	56/7206	0.0415266078221
ko05217	Basal cell carcinoma	3/922	68/7206	0.0421388071542
ko04540	Gap junction	24/922	128/7206	0.0456116150864
ko04670	Leukocyte transendothelial migration	11/922	151/7206	0.0475334390062
ko00230	Purine metabolism	34/922	194/7206	0.0498047387585