ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	94/983	145/7206	4.90511595521e-47
ko04080	Neuroactive ligand-receptor interaction	1/983	423/7206	1.76188571619e-26
ko04110	Cell cycle	71/983	145/7206	5.11213607928e-25
ko04111	Cell cycle - yeast	52/983	90/7206	6.09878881212e-23
ko03030	DNA replication	30/983	38/7206	1.22838100759e-19
ko03013	RNA transport	68/983	166/7206	1.21550483869e-18
ko03008	Ribosome biogenesis in eukaryotes	40/983	79/7206	3.11429884386e-15
ko04113	Meiosis - yeast	36/983	70/7206	4.14226088323e-14
ko04020	Calcium signaling pathway	3/983	265/7206	1.77068246884e-13
ko03460	Fanconi anemia pathway	29/983	51/7206	4.30707949358e-13
ko03410	Base excision repair	24/983	38/7206	1.91577312093e-12
ko03015	mRNA surveillance pathway	39/983	93/7206	1.36976999157e-11
ko03050	Proteasome	27/983	54/7206	1.53207835569e-10
ko04144	Endocytosis	12/983	342/7206	2.37981358882e-10
ko03430	Mismatch repair	16/983	22/7206	4.28745921187e-10
ko03440	Homologous recombination	22/983	41/7206	1.37610750495e-09
ko05217	Basal cell carcinoma	29/983	68/7206	3.67804431616e-09
ko00240	Pyrimidine metabolism	39/983	110/7206	4.92048676612e-09
ko05010	Alzheimer's disease	4/983	202/7206	8.35154141616e-09
ko04724	Glutamatergic synapse	2/983	152/7206	1.14478095426e-07
ko03420	Nucleotide excision repair	21/983	46/7206	1.29442407635e-07
ko04723	Retrograde endocannabinoid signaling	4/983	175/7206	2.81232925327e-07
ko04921	Oxytocin signaling pathway	7/983	209/7206	6.0282090994e-07
ko05012	Parkinson's disease	3/983	155/7206	6.29042741791e-07
ko04024	cAMP signaling pathway	13/983	279/7206	7.61777280299e-07
ko04060	Cytokine-cytokine receptor interaction	6/983	191/7206	1.03110424296e-06
ko05169	Epstein-Barr virus infection	54/983	206/7206	1.36793705806e-06
ko04550	Signaling pathways regulating pluripotency of stem cells	46/983	165/7206	1.42857988339e-06
ko04022	cGMP-PKG signaling pathway	8/983	216/7206	1.48036485176e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/983	182/7206	3.0737236899e-06
ko04072	Phospholipase D signaling pathway	8/983	197/7206	1.17519114662e-05
ko04621	NOD-like receptor signaling pathway	5/983	157/7206	1.60086046512e-05
ko04070	Phosphatidylinositol signaling system	2/983	112/7206	2.01394072772e-05
ko05166	HTLV-I infection	66/983	292/7206	2.4392924898e-05
ko04970	Salivary secretion	1/983	95/7206	2.73244046793e-05
ko04725	Cholinergic synapse	6/983	160/7206	3.74649897015e-05
ko04330	Notch signaling pathway	21/983	62/7206	3.92175277849e-05
ko03020	RNA polymerase	13/983	29/7206	4.26837534212e-05
ko04911	Insulin secretion	3/983	117/7206	6.24031582995e-05
ko04270	Vascular smooth muscle contraction	6/983	154/7206	7.51533850576e-05
ko04062	Chemokine signaling pathway	10/983	201/7206	9.43831761212e-05
ko04390	Hippo signaling pathway	45/983	188/7206	0.000133886174501
ko04726	Serotonergic synapse	5/983	137/7206	0.000134031274174
ko04971	Gastric acid secretion	2/983	98/7206	0.000146874909425
ko03018	RNA degradation	25/983	84/7206	0.000147062193207
ko04912	GnRH signaling pathway	4/983	122/7206	0.000164862642791
ko04014	Ras signaling pathway	18/983	279/7206	0.000165546479824
ko04713	Circadian entrainment	5/983	136/7206	0.000198015366409
ko04727	GABAergic synapse	3/983	110/7206	0.000200413758543
ko05032	Morphine addiction	3/983	110/7206	0.000200413758543
ko04610	Complement and coagulation cascades	1/983	79/7206	0.00020233269309
ko05202	Transcriptional misregulation in cancer	44/983	188/7206	0.000221766084104
ko04310	Wnt signaling pathway	43/983	181/7206	0.000246755807386
ko04630	Jak-STAT signaling pathway	5/983	132/7206	0.000273584465979
ko04925	Aldosterone synthesis and secretion	3/983	105/7206	0.000279629945911
ko04371	Apelin signaling pathway	9/983	177/7206	0.000330901599931
ko00010	Glycolysis / Gluconeogenesis	1/983	74/7206	0.000466198312587
ko04920	Adipocytokine signaling pathway	2/983	89/7206	0.000468761944768
ko00562	Inositol phosphate metabolism	2/983	89/7206	0.000468761944768
ko00564	Glycerophospholipid metabolism	3/983	99/7206	0.000585832754592
ko04114	Oocyte meiosis	34/983	139/7206	0.000625430258533
ko04650	Natural killer cell mediated cytotoxicity	3/983	97/7206	0.000855818455653
ko00230	Purine metabolism	43/983	194/7206	0.000939961651318
ko03320	PPAR signaling pathway	1/983	69/7206	0.0010945323127
ko04010	MAPK signaling pathway	25/983	321/7206	0.00112763303816
ko04659	Th17 cell differentiation	4/983	106/7206	0.00143207179109
ko04976	Bile secretion	2/983	80/7206	0.00147637051154
ko04740	Olfactory transduction	2/983	80/7206	0.00147637051154
ko03022	Basal transcription factors	14/983	44/7206	0.00151251751589
ko04931	Insulin resistance	7/983	137/7206	0.00157968569089
ko04923	Regulation of lipolysis in adipocytes	2/983	77/7206	0.00215678293423
ko04380	Osteoclast differentiation	7/983	134/7206	0.00216405205172
ko00561	Glycerolipid metabolism	1/983	63/7206	0.00242910655097
ko05224	Breast cancer	38/983	174/7206	0.00244019085432
ko04662	B cell receptor signaling pathway	3/983	88/7206	0.00254761741331
ko04260	Cardiac muscle contraction	4/983	98/7206	0.00277786012867
ko04720	Long-term potentiation	4/983	99/7206	0.00280444996269
ko04915	Estrogen signaling pathway	7/983	131/7206	0.00295678352484
ko04972	Pancreatic secretion	5/983	111/7206	0.00300713620939
ko04750	Inflammatory mediator regulation of TRP channels	6/983	122/7206	0.00304783153269
ko05203	Viral carcinogenesis	55/983	277/7206	0.00314566618636
ko04961	Endocrine and other factor-regulated calcium reabsorption	1/983	59/7206	0.00345268367925
ko04611	Platelet activation	10/983	163/7206	0.00359174805362
ko01212	Fatty acid metabolism	1/983	60/7206	0.00361326977951
ko04950	Maturity onset diabetes of the young	10/983	29/7206	0.00365680382186
ko04924	Renin secretion	3/983	86/7206	0.00377039277514
ko04120	Ubiquitin mediated proteolysis	31/983	138/7206	0.0038261872153
ko01200	Carbon metabolism	7/983	128/7206	0.00402876089082
ko04922	Glucagon signaling pathway	7/983	128/7206	0.00402876089082
ko03010	Ribosome	7/983	129/7206	0.00405465891413
ko04810	Regulation of actin cytoskeleton	21/983	264/7206	0.00452324860926
ko04138	Autophagy - yeast	3/983	81/7206	0.00512386067642
ko05120	Epithelial cell signaling in Helicobacter pylori infection	4/983	92/7206	0.00549508375888
ko04340	Hedgehog signaling pathway	16/983	58/7206	0.00573594301238
ko05231	Choline metabolism in cancer	8/983	134/7206	0.00712523781525
ko04015	Rap1 signaling pathway	23/983	278/7206	0.00724235090389
ko04066	HIF-1 signaling pathway	7/983	123/7206	0.00748682526999
ko05414	Dilated cardiomyopathy	6/983	112/7206	0.00775637480377
ko04620	Toll-like receptor signaling pathway	5/983	100/7206	0.00779353654152
ko00280	Valine, leucine and isoleucine degradation	1/983	54/7206	0.00796671135122
ko04530	Tight junction	18/983	228/7206	0.00799011113475
ko05031	Amphetamine addiction	4/983	91/7206	0.00801758794018
ko04712	Circadian rhythm - plant	4/983	7/7206	0.00855089960126
ko04914	Progesterone-mediated oocyte maturation	24/983	104/7206	0.00876003974193
ko04913	Ovarian steroidogenesis	2/983	63/7206	0.00930466180066
ko05140	Leishmaniasis	3/983	75/7206	0.0103470047334
ko05322	Systemic lupus erythematosus	32/983	151/7206	0.011183496734
ko05168	Herpes simplex infection	37/983	182/7206	0.0114211938715
ko05222	Small cell lung cancer	21/983	89/7206	0.0116737571858
ko04728	Dopaminergic synapse	14/983	185/7206	0.0123144886357
ko05152	Tuberculosis	14/983	187/7206	0.0124975139106
ko04510	Focal adhesion	20/983	240/7206	0.0127151895981
ko04261	Adrenergic signaling in cardiomyocytes	16/983	205/7206	0.0127652291837
ko00670	One carbon pool by folate	7/983	20/7206	0.0132593448371
ko04218	Cellular senescence	36/983	177/7206	0.0140772283677
ko05030	Cocaine addiction	3/983	73/7206	0.0149255613228
ko00620	Pyruvate metabolism	1/983	46/7206	0.0164475836093
ko04910	Insulin signaling pathway	13/983	172/7206	0.0176457801776
ko04612	Antigen processing and presentation	18/983	77/7206	0.018353789553
ko05142	Chagas disease (American trypanosomiasis)	9/983	130/7206	0.0202361652919
ko04142	Lysosome	11/983	151/7206	0.0219551838937
ko04670	Leukocyte transendothelial migration	11/983	151/7206	0.0219551838937
ko04668	TNF signaling pathway	8/983	120/7206	0.0220865630041
ko00071	Fatty acid degradation	1/983	45/7206	0.0257991337414
ko05146	Amoebiasis	6/983	99/7206	0.0258947144243
ko05410	Hypertrophic cardiomyopathy (HCM)	6/983	100/7206	0.0263049438548
ko04139	Mitophagy - yeast	10/983	37/7206	0.0273672585752
ko04146	Peroxisome	5/983	89/7206	0.0279293639748
ko04730	Long-term depression	4/983	78/7206	0.0291412626479
ko05160	Hepatitis C	12/983	153/7206	0.0320211403992
ko04974	Protein digestion and absorption	6/983	96/7206	0.0347479281032
ko05211	Renal cell carcinoma	6/983	96/7206	0.0347479281032
ko04978	Mineral absorption	1/983	40/7206	0.035892552814
ko05110	Vibrio cholerae infection	3/983	63/7206	0.0405568585331
ko00600	Sphingolipid metabolism	3/983	63/7206	0.0405568585331
ko04640	Hematopoietic cell lineage	3/983	64/7206	0.0414403967166
ko00970	Aminoacyl-tRNA biosynthesis	11/983	44/7206	0.0430843640693
ko04722	Neurotrophin signaling pathway	13/983	160/7206	0.0465495101018
ko05230	Central carbon metabolism in cancer	5/983	81/7206	0.0498512460545