ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	78/443	145/7206	2.1975741332e-57
ko03008	Ribosome biogenesis in eukaryotes	38/443	79/7206	1.00534394841e-25
ko03013	RNA transport	51/443	166/7206	3.3226154531e-23
ko03030	DNA replication	22/443	38/7206	1.20658523907e-17
ko04111	Cell cycle - yeast	31/443	90/7206	4.53433521078e-16
ko00240	Pyrimidine metabolism	32/443	110/7206	3.5905959511e-14
ko05322	Systemic lupus erythematosus	37/443	151/7206	1.31686718944e-13
ko04110	Cell cycle	36/443	145/7206	1.86129134195e-13
ko04113	Meiosis - yeast	22/443	70/7206	7.34824347834e-11
ko03020	RNA polymerase	14/443	29/7206	2.97945150015e-10
ko03430	Mismatch repair	11/443	22/7206	1.59656021145e-08
ko04144	Endocytosis	2/443	342/7206	1.05841687799e-07
ko03018	RNA degradation	20/443	84/7206	1.05888428637e-07
ko05034	Alcoholism	37/443	238/7206	1.16961165715e-07
ko03015	mRNA surveillance pathway	21/443	93/7206	1.35113614482e-07
ko03420	Nucleotide excision repair	14/443	46/7206	3.4925327957e-07
ko04151	PI3K-Akt signaling pathway	5/443	390/7206	2.15866750079e-06
ko03440	Homologous recombination	12/443	41/7206	3.861932435e-06
ko04015	Rap1 signaling pathway	2/443	278/7206	5.24503207421e-06
ko03460	Fanconi anemia pathway	13/443	51/7206	8.31149257687e-06
ko00230	Purine metabolism	28/443	194/7206	2.18563682867e-05
ko04024	cAMP signaling pathway	3/443	279/7206	3.4496274348e-05
ko04010	MAPK signaling pathway	5/443	321/7206	0.000109653141948
ko04014	Ras signaling pathway	4/443	279/7206	0.000181666120758
ko04022	cGMP-PKG signaling pathway	2/443	216/7206	0.000237297111979
ko04723	Retrograde endocannabinoid signaling	1/443	175/7206	0.000329237151992
ko04261	Adrenergic signaling in cardiomyocytes	2/443	205/7206	0.000332009428041
ko04810	Regulation of actin cytoskeleton	4/443	264/7206	0.000360547498946
ko03410	Base excision repair	9/443	38/7206	0.000379817304219
ko04360	Axon guidance	3/443	233/7206	0.000431810702193
ko05010	Alzheimer's disease	2/443	202/7206	0.000489291843242
ko05202	Transcriptional misregulation in cancer	24/443	188/7206	0.000559811681801
ko04530	Tight junction	3/443	228/7206	0.00062388304135
ko04071	Sphingolipid signaling pathway	1/443	162/7206	0.000709291807402
ko04145	Phagosome	1/443	162/7206	0.000709291807402
ko04072	Phospholipase D signaling pathway	2/443	197/7206	0.000723587377522
ko04621	NOD-like receptor signaling pathway	1/443	157/7206	0.00106492872787
ko04510	Focal adhesion	4/443	240/7206	0.00142699661689
ko04141	Protein processing in endoplasmic reticulum	2/443	184/7206	0.00149952777731
ko04142	Lysosome	1/443	151/7206	0.00157360463939
ko04670	Leukocyte transendothelial migration	1/443	151/7206	0.00157360463939
ko04724	Glutamatergic synapse	1/443	152/7206	0.00161141581228
ko05203	Viral carcinogenesis	30/443	277/7206	0.00204460302707
ko04062	Chemokine signaling pathway	3/443	201/7206	0.00249569271504
ko05169	Epstein-Barr virus infection	24/443	206/7206	0.00272676123588
ko04380	Osteoclast differentiation	1/443	134/7206	0.00319953143668
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/443	135/7206	0.00321527732146
ko04713	Circadian entrainment	1/443	136/7206	0.00324588868086
ko04725	Cholinergic synapse	2/443	160/7206	0.00420246341875
ko05168	Herpes simplex infection	21/443	182/7206	0.00449961016626
ko04540	Gap junction	1/443	128/7206	0.00467427507209
ko05142	Chagas disease (American trypanosomiasis)	1/443	130/7206	0.00476198258613
ko04514	Cell adhesion molecules (CAMs)	1/443	130/7206	0.00476198258613
ko04915	Estrogen signaling pathway	1/443	131/7206	0.00483798336083
ko04728	Dopaminergic synapse	3/443	185/7206	0.00485911998083
ko05152	Tuberculosis	3/443	187/7206	0.0049031282487
ko04630	Jak-STAT signaling pathway	1/443	132/7206	0.0049358555697
ko04921	Oxytocin signaling pathway	4/443	209/7206	0.00523470874238
ko04270	Vascular smooth muscle contraction	2/443	154/7206	0.00600274125292
ko04912	GnRH signaling pathway	1/443	122/7206	0.00682599097956
ko04666	Fc gamma R-mediated phagocytosis	1/443	122/7206	0.00682599097956
ko04066	HIF-1 signaling pathway	1/443	123/7206	0.00688886869611
ko05145	Toxoplasmosis	1/443	126/7206	0.00726003505045
ko05200	Pathways in cancer	17/443	492/7206	0.00836006261216
ko05418	Fluid shear stress and atherosclerosis	3/443	173/7206	0.00954362823069
ko05167	Kaposi's sarcoma-associated herpesvirus infection	4/443	191/7206	0.0136877196876
ko04727	GABAergic synapse	1/443	110/7206	0.0145319452901
ko04972	Pancreatic secretion	1/443	111/7206	0.0147214019251
ko04070	Phosphatidylinositol signaling system	1/443	112/7206	0.0149703638695
ko05231	Choline metabolism in cancer	2/443	134/7206	0.0171064622187
ko04726	Serotonergic synapse	2/443	137/7206	0.0175806400699
ko04114	Oocyte meiosis	16/443	139/7206	0.018172016884
ko04722	Neurotrophin signaling pathway	3/443	160/7206	0.0184711196375
ko04611	Platelet activation	3/443	163/7206	0.0190649254896
ko04620	Toll-like receptor signaling pathway	1/443	100/7206	0.0207505701358
ko04659	Th17 cell differentiation	1/443	106/7206	0.0218824777451
ko04139	Mitophagy - yeast	6/443	37/7206	0.0238905725479
ko01200	Carbon metabolism	2/443	128/7206	0.0242064462788
ko04371	Apelin signaling pathway	4/443	177/7206	0.0254039615449
ko05160	Hepatitis C	3/443	153/7206	0.0254868200599
ko05205	Proteoglycans in cancer	8/443	271/7206	0.0271306883727
ko04650	Natural killer cell mediated cytotoxicity	1/443	97/7206	0.0304432501203
ko05100	Bacterial invasion of epithelial cells	1/443	99/7206	0.0313249536501
ko04750	Inflammatory mediator regulation of TRP channels	2/443	122/7206	0.0341878751115
ko04910	Insulin signaling pathway	4/443	172/7206	0.0348090492909
ko04660	T cell receptor signaling pathway	2/443	124/7206	0.0349446345997
ko04917	Prolactin signaling pathway	1/443	87/7206	0.0432284822844
ko05133	Pertussis	1/443	87/7206	0.0432284822844
ko04662	B cell receptor signaling pathway	1/443	88/7206	0.0432372274611
ko04146	Peroxisome	1/443	89/7206	0.0434003587229
ko05323	Rheumatoid arthritis	1/443	89/7206	0.0434003587229
ko00562	Inositol phosphate metabolism	1/443	89/7206	0.0434003587229
ko04390	Hippo signaling pathway	5/443	188/7206	0.0440100259012
ko04931	Insulin resistance	3/443	137/7206	0.0477537296641
ko05164	Influenza A	4/443	167/7206	0.0477660980892
ko04916	Melanogenesis	3/443	142/7206	0.0491672438834