ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/960	423/7206	3.94295985312e-35
ko05033	Nicotine addiction	39/960	56/7206	3.68098265362e-22
ko04724	Glutamatergic synapse	66/960	152/7206	2.60968208774e-20
ko04727	GABAergic synapse	45/960	110/7206	4.37139613651e-13
ko05032	Morphine addiction	45/960	110/7206	4.37139613651e-13
ko04713	Circadian entrainment	51/960	136/7206	6.87424488425e-13
ko04728	Dopaminergic synapse	61/960	185/7206	2.72737555111e-12
ko04725	Cholinergic synapse	54/960	160/7206	1.83276175867e-11
ko04723	Retrograde endocannabinoid signaling	57/960	175/7206	3.51727295592e-11
ko04726	Serotonergic synapse	47/960	137/7206	2.0412148968e-10
ko04721	Synaptic vesicle cycle	33/960	80/7206	4.67099781236e-10
ko04742	Taste transduction	27/960	61/7206	2.80649671884e-09
ko04976	Bile secretion	31/960	80/7206	9.61339170076e-09
ko04744	Phototransduction	19/960	36/7206	1.79972439829e-08
ko04911	Insulin secretion	39/960	117/7206	1.81566218606e-08
ko03040	Spliceosome	1/960	145/7206	3.67909881077e-08
ko04972	Pancreatic secretion	37/960	111/7206	4.21976252357e-08
ko04024	cAMP signaling pathway	70/960	279/7206	6.95638687657e-08
ko04974	Protein digestion and absorption	32/960	96/7206	3.46848184137e-07
ko05166	HTLV-I infection	13/960	292/7206	4.06284804174e-07
ko04120	Ubiquitin mediated proteolysis	2/960	138/7206	8.57199869868e-07
ko05162	Measles	1/960	120/7206	1.00298006361e-06
ko05031	Amphetamine addiction	30/960	91/7206	1.05132500254e-06
ko05164	Influenza A	4/960	167/7206	1.36131919637e-06
ko05203	Viral carcinogenesis	13/960	277/7206	2.10139787943e-06
ko04740	Olfactory transduction	27/960	80/7206	2.1709094051e-06
ko04261	Adrenergic signaling in cardiomyocytes	52/960	205/7206	2.96202109182e-06
ko04020	Calcium signaling pathway	62/960	265/7206	5.05392349875e-06
ko04514	Cell adhesion molecules (CAMs)	37/960	130/7206	5.08807071811e-06
ko04964	Proximal tubule bicarbonate reclamation	14/960	29/7206	5.59782369154e-06
ko03013	RNA transport	5/960	166/7206	7.80100556506e-06
ko05030	Cocaine addiction	24/960	73/7206	1.3187497604e-05
ko05168	Herpes simplex infection	7/960	182/7206	2.14831867445e-05
ko04978	Mineral absorption	16/960	40/7206	2.37936347444e-05
ko04921	Oxytocin signaling pathway	50/960	209/7206	2.76048926968e-05
ko04971	Gastric acid secretion	29/960	98/7206	2.95149076348e-05
ko04970	Salivary secretion	28/960	95/7206	4.44429370171e-05
ko04260	Cardiac muscle contraction	28/960	98/7206	6.11427770592e-05
ko04141	Protein processing in endoplasmic reticulum	8/960	184/7206	6.42000023113e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/960	74/7206	7.8585551571e-05
ko05169	Epstein-Barr virus infection	10/960	206/7206	9.72339166164e-05
ko05205	Proteoglycans in cancer	17/960	271/7206	0.000238989292391
ko05161	Hepatitis B	8/960	173/7206	0.000242489994539
ko04110	Cell cycle	6/960	145/7206	0.000302662750617
ko04621	NOD-like receptor signaling pathway	7/960	157/7206	0.000319683277083
ko03008	Ribosome biogenesis in eukaryotes	1/960	79/7206	0.000321301539512
ko04630	Jak-STAT signaling pathway	5/960	132/7206	0.000395874461731
ko04150	mTOR signaling pathway	10/960	184/7206	0.000607572618663
ko05322	Systemic lupus erythematosus	7/960	151/7206	0.000615713560926
ko04140	Autophagy - animal	8/960	164/7206	0.000642667850079
ko00830	Retinol metabolism	14/960	42/7206	0.000711516681522
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/960	182/7206	0.00082542945208
ko05220	Chronic myeloid leukemia	2/960	85/7206	0.0010300079109
ko04060	Cytokine-cytokine receptor interaction	11/960	191/7206	0.00108163856322
ko05211	Renal cell carcinoma	3/960	96/7206	0.00125127402937
ko04720	Long-term potentiation	25/960	99/7206	0.00142732425279
ko05016	Huntington's disease	14/960	215/7206	0.00206674767368
ko00350	Tyrosine metabolism	11/960	33/7206	0.00261544183978
ko04745	Phototransduction - fly	12/960	38/7206	0.00283875431342
ko04933	AGE-RAGE signaling pathway in diabetic complications	7/960	135/7206	0.00301256968709
ko04660	T cell receptor signaling pathway	6/960	124/7206	0.00304505150583
ko04218	Cellular senescence	11/960	177/7206	0.00335782695955
ko04550	Signaling pathways regulating pluripotency of stem cells	10/960	165/7206	0.00356541083682
ko02010	ABC transporters	12/960	39/7206	0.00361345681629
ko05200	Pathways in cancer	45/960	492/7206	0.00384017339789
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/960	79/7206	0.00391487175494
ko04966	Collecting duct acid secretion	9/960	26/7206	0.00476543936618
ko04611	Platelet activation	10/960	163/7206	0.00479141633238
ko03018	RNA degradation	3/960	84/7206	0.0052935125101
ko04924	Renin secretion	21/960	86/7206	0.00573681279036
ko04614	Renin-angiotensin system	7/960	18/7206	0.00609541761699
ko05206	MicroRNAs in cancer	12/960	177/7206	0.00700175658212
ko04217	Necroptosis	12/960	178/7206	0.00702598405092
ko04931	Insulin resistance	8/960	137/7206	0.00719918044962
ko04925	Aldosterone synthesis and secretion	24/960	105/7206	0.0083286889303
ko00643	Styrene degradation	3/960	4/7206	0.00849232685618
ko00910	Nitrogen metabolism	7/960	19/7206	0.00856034526917
ko05224	Breast cancer	12/960	174/7206	0.00912198086728
ko04612	Antigen processing and presentation	3/960	77/7206	0.0105047709082
ko05215	Prostate cancer	6/960	111/7206	0.0106255182782
ko04142	Lysosome	10/960	151/7206	0.0108927165997
ko00510	N-Glycan biosynthesis	1/960	50/7206	0.0112300885914
ko04810	Regulation of actin cytoskeleton	22/960	264/7206	0.0126551221372
ko04330	Notch signaling pathway	2/960	62/7206	0.0136222781565
ko04668	TNF signaling pathway	7/960	120/7206	0.0138461480057
ko04210	Apoptosis	13/960	180/7206	0.0139648016004
ko04010	MAPK signaling pathway	58/960	321/7206	0.0144863236828
ko04750	Inflammatory mediator regulation of TRP channels	26/960	122/7206	0.0146196547483
ko04064	NF-kappa B signaling pathway	5/960	96/7206	0.0148815144666
ko04730	Long-term depression	18/960	78/7206	0.0175347593157
ko04914	Progesterone-mediated oocyte maturation	6/960	104/7206	0.0193534783382
ko04113	Meiosis - yeast	3/960	70/7206	0.0207360595063
ko04137	Mitophagy - animal	4/960	82/7206	0.0209607581451
ko04214	Apoptosis - fly	3/960	72/7206	0.0214808556977
ko04626	Plant-pathogen interaction	6/960	18/7206	0.0246676398016
ko04540	Gap junction	26/960	128/7206	0.0249263270707
ko03420	Nucleotide excision repair	1/960	46/7206	0.0259694408646
ko04620	Toll-like receptor signaling pathway	6/960	100/7206	0.0259695170707
ko05321	Inflammatory bowel disease (IBD)	2/960	56/7206	0.0281470337646
ko05217	Basal cell carcinoma	3/960	68/7206	0.0294733854842
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/960	14/7206	0.0294935873695
ko04022	cGMP-PKG signaling pathway	40/960	216/7206	0.0320200166343
ko04510	Focal adhesion	21/960	240/7206	0.0332826561309
ko05410	Hypertrophic cardiomyopathy (HCM)	21/960	100/7206	0.036196429128
ko04068	FoxO signaling pathway	13/960	167/7206	0.0370835184677
ko04664	Fc epsilon RI signaling pathway	4/960	77/7206	0.0406501816108
ko04910	Insulin signaling pathway	14/960	172/7206	0.0409384023914
ko04975	Fat digestion and absorption	9/960	35/7206	0.0424846789217
ko01521	EGFR tyrosine kinase inhibitor resistance	7/960	106/7206	0.0425539076173
ko04211	Longevity regulating pathway	9/960	123/7206	0.0450328243215