ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	199/1227	423/7206	6.42871645788e-50
ko04724	Glutamatergic synapse	95/1227	152/7206	6.98502472096e-37
ko05033	Nicotine addiction	49/1227	56/7206	6.39780316394e-31
ko04713	Circadian entrainment	79/1227	136/7206	1.08204668574e-27
ko04727	GABAergic synapse	69/1227	110/7206	3.7882820757e-27
ko05032	Morphine addiction	69/1227	110/7206	3.7882820757e-27
ko04728	Dopaminergic synapse	88/1227	185/7206	1.77871402029e-22
ko04725	Cholinergic synapse	78/1227	160/7206	7.34774404781e-21
ko04024	cAMP signaling pathway	108/1227	279/7206	1.3203377763e-18
ko04723	Retrograde endocannabinoid signaling	78/1227	175/7206	6.26979521702e-18
ko04020	Calcium signaling pathway	101/1227	265/7206	5.62605784208e-17
ko04726	Serotonergic synapse	65/1227	137/7206	8.27810016319e-17
ko04721	Synaptic vesicle cycle	45/1227	80/7206	1.55179853352e-15
ko04911	Insulin secretion	56/1227	117/7206	7.36946388841e-15
ko04744	Phototransduction	27/1227	36/7206	2.65610459867e-14
ko05031	Amphetamine addiction	46/1227	91/7206	1.5600344196e-13
ko04921	Oxytocin signaling pathway	79/1227	209/7206	3.5758051298e-13
ko04720	Long-term potentiation	45/1227	99/7206	3.1776223165e-11
ko04742	Taste transduction	33/1227	61/7206	4.0993453538e-11
ko04261	Adrenergic signaling in cardiomyocytes	73/1227	205/7206	7.91909726363e-11
ko04022	cGMP-PKG signaling pathway	75/1227	216/7206	1.52795767295e-10
ko05030	Cocaine addiction	35/1227	73/7206	8.3987403397e-10
ko03040	Spliceosome	2/1227	145/7206	9.71346702755e-10
ko03010	Ribosome	1/1227	129/7206	1.55310512003e-09
ko04970	Salivary secretion	41/1227	95/7206	1.68118663504e-09
ko04925	Aldosterone synthesis and secretion	43/1227	105/7206	7.40637546107e-09
ko05322	Systemic lupus erythematosus	4/1227	151/7206	3.60281887753e-08
ko04740	Olfactory transduction	34/1227	80/7206	6.60856550857e-08
ko04971	Gastric acid secretion	38/1227	98/7206	2.18799936672e-07
ko04070	Phosphatidylinositol signaling system	41/1227	112/7206	6.43326366615e-07
ko04060	Cytokine-cytokine receptor interaction	10/1227	191/7206	1.19735113529e-06
ko04730	Long-term depression	31/1227	78/7206	1.90704288663e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	30/1227	74/7206	2.24942172305e-06
ko03013	RNA transport	8/1227	166/7206	2.88689434762e-06
ko05203	Viral carcinogenesis	21/1227	277/7206	4.24632048763e-06
ko05168	Herpes simplex infection	10/1227	182/7206	4.96015740211e-06
ko04072	Phospholipase D signaling pathway	58/1227	197/7206	1.19805267212e-05
ko04745	Phototransduction - fly	18/1227	38/7206	1.38383609871e-05
ko04110	Cell cycle	7/1227	145/7206	1.57207633708e-05
ko04710	Circadian rhythm	19/1227	43/7206	2.75910525235e-05
ko04924	Renin secretion	30/1227	86/7206	6.15112982499e-05
ko04540	Gap junction	40/1227	128/7206	6.84747562803e-05
ko04141	Protein processing in endoplasmic reticulum	13/1227	184/7206	9.25442812028e-05
ko04371	Apelin signaling pathway	51/1227	177/7206	9.87368282736e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1227	79/7206	0.000111596311226
ko04010	MAPK signaling pathway	81/1227	321/7206	0.000135243317277
ko04915	Estrogen signaling pathway	40/1227	131/7206	0.000136658840002
ko04972	Pancreatic secretion	35/1227	111/7206	0.000171120482514
ko04360	Axon guidance	62/1227	233/7206	0.00017976677698
ko05169	Epstein-Barr virus infection	17/1227	206/7206	0.0003235161939
ko04621	NOD-like receptor signaling pathway	11/1227	157/7206	0.000343689711741
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1227	79/7206	0.000461615191966
ko04514	Cell adhesion molecules (CAMs)	38/1227	130/7206	0.000541028845282
ko04750	Inflammatory mediator regulation of TRP channels	36/1227	122/7206	0.000573060897185
ko04610	Complement and coagulation cascades	3/1227	79/7206	0.000717432385295
ko05164	Influenza A	13/1227	167/7206	0.000770912979631
ko04922	Glucagon signaling pathway	37/1227	128/7206	0.000775270907916
ko04014	Ras signaling pathway	69/1227	279/7206	0.000826552354665
ko00520	Amino sugar and nucleotide sugar metabolism	1/1227	55/7206	0.000849500650145
ko04064	NF-kappa B signaling pathway	5/1227	96/7206	0.000874964530959
ko04923	Regulation of lipolysis in adipocytes	25/1227	77/7206	0.0010773439338
ko04930	Type II diabetes mellitus	19/1227	54/7206	0.00145206526599
ko05414	Dilated cardiomyopathy	32/1227	112/7206	0.00212981576884
ko04630	Jak-STAT signaling pathway	10/1227	132/7206	0.00221054893676
ko04711	Circadian rhythm - fly	7/1227	13/7206	0.00269946698779
ko03420	Nucleotide excision repair	1/1227	46/7206	0.00283980329749
ko04973	Carbohydrate digestion and absorption	15/1227	42/7206	0.00310805928968
ko05162	Measles	9/1227	120/7206	0.00314991894733
ko04612	Antigen processing and presentation	4/1227	77/7206	0.00332804954079
ko04260	Cardiac muscle contraction	28/1227	98/7206	0.00409621671008
ko03022	Basal transcription factors	1/1227	44/7206	0.00426373320169
ko05140	Leishmaniasis	4/1227	75/7206	0.00478994703159
ko04964	Proximal tubule bicarbonate reclamation	11/1227	29/7206	0.00583336924371
ko04626	Plant-pathogen interaction	8/1227	18/7206	0.00604384013387
ko04330	Notch signaling pathway	3/1227	62/7206	0.00625170645127
ko04622	RIG-I-like receptor signaling pathway	3/1227	62/7206	0.00625170645127
ko04960	Aldosterone-regulated sodium reabsorption	14/1227	41/7206	0.00638977925338
ko05205	Proteoglycans in cancer	30/1227	271/7206	0.00646957178579
ko04966	Collecting duct acid secretion	10/1227	26/7206	0.00755928698133
ko04120	Ubiquitin mediated proteolysis	12/1227	138/7206	0.00805295458632
ko00562	Inositol phosphate metabolism	25/1227	89/7206	0.00976758512755
ko05161	Hepatitis B	17/1227	173/7206	0.0100889716824
ko00240	Pyrimidine metabolism	9/1227	110/7206	0.0102431087862
ko05166	HTLV-I infection	34/1227	292/7206	0.0109090678637
ko04350	TGF-beta signaling pathway	8/1227	103/7206	0.0113374456428
ko03410	Base excision repair	1/1227	38/7206	0.0149536956439
ko04142	Lysosome	15/1227	151/7206	0.0160738907915
ko04976	Bile secretion	22/1227	80/7206	0.0163699749147
ko04270	Vascular smooth muscle contraction	38/1227	154/7206	0.0164951129959
ko04214	Apoptosis - fly	5/1227	72/7206	0.0178634248825
ko05200	Pathways in cancer	65/1227	492/7206	0.0182439299157
ko05321	Inflammatory bowel disease (IBD)	3/1227	56/7206	0.0186388705666
ko04658	Th1 and Th2 cell differentiation	8/1227	96/7206	0.0197448984923
ko04217	Necroptosis	19/1227	178/7206	0.020131901782
ko04918	Thyroid hormone synthesis	23/1227	86/7206	0.0205463558232
ko05016	Huntington's disease	24/1227	215/7206	0.020852510069
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1227	14/7206	0.0209827829523
ko04657	IL-17 signaling pathway	7/1227	87/7206	0.0214523029966
ko00860	Porphyrin and chlorophyll metabolism	1/1227	34/7206	0.0216920760281
ko05222	Small cell lung cancer	7/1227	89/7206	0.0219641643357
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1227	100/7206	0.0219930563591
ko05034	Alcoholism	54/1227	238/7206	0.0222950069768
ko05145	Toxoplasmosis	12/1227	126/7206	0.0225979051598
ko04113	Meiosis - yeast	5/1227	70/7206	0.0245432559102
ko05144	Malaria	2/1227	45/7206	0.0259465024558
ko05231	Choline metabolism in cancer	33/1227	134/7206	0.0266218774953
ko04912	GnRH signaling pathway	30/1227	122/7206	0.0288094820227
ko05202	Transcriptional misregulation in cancer	21/1227	188/7206	0.0302107248407
ko05130	Pathogenic Escherichia coli infection	6/1227	77/7206	0.0315109373835
ko05214	Glioma	21/1227	79/7206	0.0335077112355
ko04510	Focal adhesion	29/1227	240/7206	0.0362278250601
ko05230	Central carbon metabolism in cancer	21/1227	81/7206	0.0373736896221
ko03018	RNA degradation	7/1227	84/7206	0.0392884111363
ko04115	p53 signaling pathway	6/1227	74/7206	0.0421306410753
ko05206	MicroRNAs in cancer	20/1227	177/7206	0.0423566334922
ko05110	Vibrio cholerae infection	17/1227	63/7206	0.0425169503729
ko04932	Non-alcoholic fatty liver disease (NAFLD)	21/1227	182/7206	0.0457088992244
ko04146	Peroxisome	8/1227	89/7206	0.0458381600987