ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	110/548	423/7206	2.17765175766e-33
ko04724	Glutamatergic synapse	61/548	152/7206	7.46188745048e-30
ko05033	Nicotine addiction	34/548	56/7206	1.50582952511e-24
ko04713	Circadian entrainment	46/548	136/7206	4.05494781465e-19
ko04728	Dopaminergic synapse	54/548	185/7206	6.18055300359e-19
ko04727	GABAergic synapse	41/548	110/7206	6.29482551591e-19
ko05032	Morphine addiction	41/548	110/7206	6.29482551591e-19
ko04723	Retrograde endocannabinoid signaling	52/548	175/7206	1.20788043181e-18
ko04024	cAMP signaling pathway	61/548	279/7206	1.22512911778e-14
ko04911	Insulin secretion	37/548	117/7206	1.58013774757e-14
ko04921	Oxytocin signaling pathway	48/548	209/7206	1.47908305092e-12
ko04721	Synaptic vesicle cycle	28/548	80/7206	1.63423363386e-12
ko04020	Calcium signaling pathway	55/548	265/7206	2.60456942359e-12
ko04725	Cholinergic synapse	40/548	160/7206	6.8997959715e-12
ko05031	Amphetamine addiction	29/548	91/7206	9.5766174914e-12
ko04726	Serotonergic synapse	36/548	137/7206	1.70373759099e-11
ko04742	Taste transduction	23/548	61/7206	2.83916535486e-11
ko04261	Adrenergic signaling in cardiomyocytes	42/548	205/7206	1.75648279648e-09
ko05030	Cocaine addiction	23/548	73/7206	1.80007024857e-09
ko04720	Long-term potentiation	27/548	99/7206	2.53011405057e-09
ko04970	Salivary secretion	23/548	95/7206	4.19245259254e-07
ko04972	Pancreatic secretion	25/548	111/7206	5.7993277148e-07
ko04925	Aldosterone synthesis and secretion	24/548	105/7206	7.3347055253e-07
ko04971	Gastric acid secretion	23/548	98/7206	7.59882026457e-07
ko04730	Long-term depression	19/548	78/7206	3.8735791584e-06
ko04010	MAPK signaling pathway	47/548	321/7206	1.16154712173e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	17/548	74/7206	2.85535383577e-05
ko04260	Cardiac muscle contraction	20/548	98/7206	3.67092812918e-05
ko05164	Influenza A	1/548	167/7206	4.29791160093e-05
ko04060	Cytokine-cytokine receptor interaction	2/548	191/7206	7.26650553189e-05
ko04072	Phospholipase D signaling pathway	31/548	197/7206	9.45284462855e-05
ko05203	Viral carcinogenesis	6/548	277/7206	0.000111739375213
ko04514	Cell adhesion molecules (CAMs)	23/548	130/7206	0.000135320507788
ko03040	Spliceosome	1/548	145/7206	0.000203912348483
ko04750	Inflammatory mediator regulation of TRP channels	21/548	122/7206	0.00036525147335
ko04745	Phototransduction - fly	10/548	38/7206	0.000400761126243
ko04120	Ubiquitin mediated proteolysis	1/548	138/7206	0.000467895719249
ko04540	Gap junction	21/548	128/7206	0.000633399022358
ko05169	Epstein-Barr virus infection	4/548	206/7206	0.000701270671045
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/548	79/7206	0.000764105936695
ko04070	Phosphatidylinositol signaling system	19/548	112/7206	0.000837228020519
ko04740	Olfactory transduction	15/548	80/7206	0.000876176665184
ko05322	Systemic lupus erythematosus	2/548	151/7206	0.000939545214387
ko04022	cGMP-PKG signaling pathway	30/548	216/7206	0.00103352230091
ko04964	Proximal tubule bicarbonate reclamation	8/548	29/7206	0.00108849794499
ko04915	Estrogen signaling pathway	21/548	131/7206	0.00116035669133
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/548	59/7206	0.00135590334327
ko05110	Vibrio cholerae infection	12/548	63/7206	0.00244554187222
ko05168	Herpes simplex infection	4/548	182/7206	0.00261608911799
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/548	14/7206	0.00280434668262
ko05215	Prostate cancer	1/548	111/7206	0.00312388860801
ko04630	Jak-STAT signaling pathway	2/548	132/7206	0.00410679210481
ko05414	Dilated cardiomyopathy	17/548	112/7206	0.00583534944707
ko04110	Cell cycle	3/548	145/7206	0.00653360735876
ko04550	Signaling pathways regulating pluripotency of stem cells	4/548	165/7206	0.00695616810138
ko03013	RNA transport	4/548	166/7206	0.00700264846258
ko04141	Protein processing in endoplasmic reticulum	5/548	184/7206	0.00708219161858
ko04510	Focal adhesion	8/548	240/7206	0.00874338096525
ko04626	Plant-pathogen interaction	5/548	18/7206	0.00930814124317
ko05205	Proteoglycans in cancer	10/548	271/7206	0.00989734394103
ko04966	Collecting duct acid secretion	6/548	26/7206	0.0116542381841
ko05034	Alcoholism	29/548	238/7206	0.0120691865576
ko04218	Cellular senescence	5/548	177/7206	0.0135189601792
ko04924	Renin secretion	13/548	86/7206	0.0135754615834
ko04621	NOD-like receptor signaling pathway	4/548	157/7206	0.013583853963
ko04976	Bile secretion	12/548	80/7206	0.0187452331288
ko04930	Type II diabetes mellitus	9/548	54/7206	0.0194184842178
ko05410	Hypertrophic cardiomyopathy (HCM)	14/548	100/7206	0.0217452485338
ko04150	mTOR signaling pathway	6/548	184/7206	0.0229747558729
ko04350	TGF-beta signaling pathway	2/548	103/7206	0.0232836872099
ko04140	Autophagy - animal	5/548	164/7206	0.0240915512864
ko01524	Platinum drug resistance	1/548	76/7206	0.0289254039425
ko04610	Complement and coagulation cascades	1/548	79/7206	0.0296431071664
ko05231	Choline metabolism in cancer	17/548	134/7206	0.0317740505628
ko04918	Thyroid hormone synthesis	12/548	86/7206	0.0373279326397
ko04151	PI3K-Akt signaling pathway	19/548	390/7206	0.0384669629856
ko05161	Hepatitis B	6/548	173/7206	0.0403894416755
ko00680	Methane metabolism	6/548	34/7206	0.0407386372779
ko05166	HTLV-I infection	13/548	292/7206	0.0414585745282
ko04214	Apoptosis - fly	1/548	72/7206	0.0420583763744
ko00562	Inositol phosphate metabolism	12/548	89/7206	0.0432549850128
ko00240	Pyrimidine metabolism	3/548	110/7206	0.046481252073