ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/955	423/7206	2.05563517767e-35
ko04724	Glutamatergic synapse	74/955	152/7206	1.18658759761e-26
ko05033	Nicotine addiction	42/955	56/7206	5.58242151765e-26
ko05032	Morphine addiction	54/955	110/7206	6.22896434178e-20
ko04713	Circadian entrainment	61/955	136/7206	7.746337396e-20
ko04728	Dopaminergic synapse	73/955	185/7206	1.451680539e-19
ko04727	GABAergic synapse	53/955	110/7206	4.07949349959e-19
ko04725	Cholinergic synapse	65/955	160/7206	2.63334721242e-18
ko04721	Synaptic vesicle cycle	41/955	80/7206	2.83063019695e-16
ko04723	Retrograde endocannabinoid signaling	65/955	175/7206	5.6106852939e-16
ko04911	Insulin secretion	48/955	117/7206	5.0982587658e-14
ko04024	cAMP signaling pathway	83/955	279/7206	1.7563524081e-13
ko04726	Serotonergic synapse	51/955	137/7206	7.79348279833e-13
ko04020	Calcium signaling pathway	76/955	265/7206	1.46530209389e-11
ko04921	Oxytocin signaling pathway	63/955	209/7206	1.19458365157e-10
ko05031	Amphetamine addiction	36/955	91/7206	2.65968612975e-10
ko04742	Taste transduction	28/955	61/7206	4.46326730718e-10
ko04720	Long-term potentiation	35/955	99/7206	1.5551873577e-08
ko04744	Phototransduction	19/955	36/7206	1.649087748e-08
ko04261	Adrenergic signaling in cardiomyocytes	57/955	205/7206	2.37416022482e-08
ko04925	Aldosterone synthesis and secretion	36/955	105/7206	2.44521091403e-08
ko05322	Systemic lupus erythematosus	2/955	151/7206	1.7209465734e-07
ko04970	Salivary secretion	32/955	95/7206	2.34040632121e-07
ko03040	Spliceosome	2/955	145/7206	3.85774258516e-07
ko04971	Gastric acid secretion	31/955	98/7206	2.50547984318e-06
ko05030	Cocaine addiction	25/955	73/7206	3.46563927218e-06
ko04070	Phosphatidylinositol signaling system	33/955	112/7206	6.55763564612e-06
ko03013	RNA transport	5/955	166/7206	7.82533283046e-06
ko05168	Herpes simplex infection	7/955	182/7206	3.13983006543e-05
ko04010	MAPK signaling pathway	69/955	321/7206	3.14648920009e-05
ko04514	Cell adhesion molecules (CAMs)	35/955	130/7206	3.38475580145e-05
ko04750	Inflammatory mediator regulation of TRP channels	33/955	122/7206	3.80504489164e-05
ko04745	Phototransduction - fly	15/955	38/7206	4.83078396532e-05
ko04730	Long-term depression	24/955	78/7206	5.59853047729e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/955	74/7206	7.56972343388e-05
ko04360	Axon guidance	52/955	233/7206	0.000109899699399
ko05164	Influenza A	7/955	167/7206	0.000118569565637
ko04060	Cytokine-cytokine receptor interaction	9/955	191/7206	0.000129139309144
ko05203	Viral carcinogenesis	17/955	277/7206	0.000135576773641
ko04072	Phospholipase D signaling pathway	45/955	197/7206	0.000169883148375
ko04120	Ubiquitin mediated proteolysis	5/955	138/7206	0.000196076815301
ko04022	cGMP-PKG signaling pathway	48/955	216/7206	0.00021785900652
ko04141	Protein processing in endoplasmic reticulum	9/955	184/7206	0.000243446884484
ko04972	Pancreatic secretion	29/955	111/7206	0.000312688312409
ko03008	Ribosome biogenesis in eukaryotes	1/955	79/7206	0.000317809688828
ko04621	NOD-like receptor signaling pathway	7/955	157/7206	0.000321883823848
ko04710	Circadian rhythm	14/955	43/7206	0.000880274319828
ko04014	Ras signaling pathway	56/955	279/7206	0.00112484665267
ko04966	Collecting duct acid secretion	10/955	26/7206	0.00113487080494
ko04110	Cell cycle	7/955	145/7206	0.00117366093583
ko04626	Plant-pathogen interaction	8/955	18/7206	0.0011817922563
ko04612	Antigen processing and presentation	2/955	77/7206	0.00214093780386
ko04915	Estrogen signaling pathway	30/955	131/7206	0.00244726495691
ko04146	Peroxisome	3/955	89/7206	0.00255920736147
ko04964	Proximal tubule bicarbonate reclamation	10/955	29/7206	0.00294675937283
ko04540	Gap junction	29/955	128/7206	0.00339970216392
ko00330	Arginine and proline metabolism	1/955	61/7206	0.00355735508
ko05110	Vibrio cholerae infection	17/955	63/7206	0.00401466007928
ko04630	Jak-STAT signaling pathway	7/955	132/7206	0.00410333599955
ko05016	Huntington's disease	15/955	215/7206	0.0041062518813
ko04740	Olfactory transduction	20/955	80/7206	0.00414008733791
ko05162	Measles	6/955	120/7206	0.0041715328843
ko04260	Cardiac muscle contraction	23/955	98/7206	0.00611655372666
ko00562	Inositol phosphate metabolism	21/955	89/7206	0.0068553120452
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/955	79/7206	0.00734642973505
ko00280	Valine, leucine and isoleucine degradation	1/955	54/7206	0.00765623062226
ko04960	Aldosterone-regulated sodium reabsorption	12/955	41/7206	0.00832427842688
ko04924	Renin secretion	20/955	86/7206	0.00977366310993
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/955	59/7206	0.0106841440007
ko04064	NF-kappa B signaling pathway	5/955	96/7206	0.0148949246604
ko05140	Leishmaniasis	3/955	75/7206	0.0150857927954
ko05169	Epstein-Barr virus infection	16/955	206/7206	0.0162340798702
ko04962	Vasopressin-regulated water reabsorption	14/955	58/7206	0.0195538277881
ko04711	Circadian rhythm - fly	5/955	13/7206	0.020793051554
ko05161	Hepatitis B	13/955	173/7206	0.0227330189367
ko03022	Basal transcription factors	1/955	44/7206	0.0245867823409
ko05144	Malaria	1/955	45/7206	0.0249218965658
ko04930	Type II diabetes mellitus	13/955	54/7206	0.0257049713597
ko03420	Nucleotide excision repair	1/955	46/7206	0.0257525018787
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/955	182/7206	0.0260367354205
ko05166	HTLV-I infection	26/955	292/7206	0.0271202728713
ko05231	Choline metabolism in cancer	27/955	134/7206	0.0275917954317
ko05205	Proteoglycans in cancer	24/955	271/7206	0.0282196145601
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/955	14/7206	0.0288948161864
ko04916	Melanogenesis	28/955	142/7206	0.0323801439214
ko04217	Necroptosis	14/955	178/7206	0.0327336785698
ko05414	Dilated cardiomyopathy	23/955	112/7206	0.0335590408068
ko04015	Rap1 signaling pathway	49/955	278/7206	0.0373916265078
ko00590	Arachidonic acid metabolism	2/955	52/7206	0.040023262693
ko05130	Pathogenic Escherichia coli infection	4/955	77/7206	0.040345236521
ko04114	Oocyte meiosis	27/955	139/7206	0.0419405080551
ko05214	Glioma	17/955	79/7206	0.0428701755819
ko04976	Bile secretion	17/955	80/7206	0.044736256105
ko05145	Toxoplasmosis	9/955	126/7206	0.0455089838018