ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	64/453	145/7206	1.90481289361e-39
ko04111	Cell cycle - yeast	38/453	90/7206	8.32946175109e-23
ko03013	RNA transport	51/453	166/7206	9.396616118e-23
ko04110	Cell cycle	47/453	145/7206	3.89304059678e-22
ko03030	DNA replication	25/453	38/7206	1.21776827371e-21
ko04113	Meiosis - yeast	25/453	70/7206	2.19200574618e-13
ko03430	Mismatch repair	13/453	22/7206	5.98142729208e-11
ko03008	Ribosome biogenesis in eukaryotes	23/453	79/7206	2.40763390584e-10
ko03015	mRNA surveillance pathway	25/453	93/7206	2.62112458941e-10
ko03420	Nucleotide excision repair	17/453	46/7206	8.91001318445e-10
ko04144	Endocytosis	1/453	342/7206	7.08826254169e-09
ko00240	Pyrimidine metabolism	23/453	110/7206	2.30780768569e-07
ko03410	Base excision repair	13/453	38/7206	2.56277583123e-07
ko04810	Regulation of actin cytoskeleton	2/453	264/7206	7.6598865554e-06
ko03460	Fanconi anemia pathway	13/453	51/7206	1.05951644837e-05
ko04015	Rap1 signaling pathway	3/453	278/7206	2.3686328488e-05
ko04014	Ras signaling pathway	3/453	279/7206	2.37277313697e-05
ko03440	Homologous recombination	11/453	41/7206	3.02509747126e-05
ko04921	Oxytocin signaling pathway	1/453	209/7206	3.17457982439e-05
ko05010	Alzheimer's disease	1/453	202/7206	4.65199847427e-05
ko04010	MAPK signaling pathway	5/453	321/7206	5.2482796998e-05
ko03018	RNA degradation	16/453	84/7206	5.46951541353e-05
ko04060	Cytokine-cytokine receptor interaction	1/453	191/7206	0.000104029705336
ko04024	cAMP signaling pathway	4/453	279/7206	0.000127217846016
ko04114	Oocyte meiosis	21/453	139/7206	0.000142725572459
ko04022	cGMP-PKG signaling pathway	2/453	216/7206	0.000159038660844
ko05166	HTLV-I infection	34/453	292/7206	0.000466954587879
ko04611	Platelet activation	1/453	163/7206	0.000472954586936
ko04120	Ubiquitin mediated proteolysis	20/453	138/7206	0.000478244677894
ko04621	NOD-like receptor signaling pathway	1/453	157/7206	0.00069555510645
ko04725	Cholinergic synapse	1/453	160/7206	0.000724487718394
ko04151	PI3K-Akt signaling pathway	10/453	390/7206	0.000814583471507
ko04670	Leukocyte transendothelial migration	1/453	151/7206	0.00102221919491
ko04270	Vascular smooth muscle contraction	1/453	154/7206	0.00106927954286
ko05012	Parkinson's disease	1/453	155/7206	0.00109611509812
ko03022	Basal transcription factors	9/453	44/7206	0.00139152540786
ko04910	Insulin signaling pathway	2/453	172/7206	0.00208799849
ko04071	Sphingolipid signaling pathway	2/453	162/7206	0.00292687116126
ko04915	Estrogen signaling pathway	1/453	131/7206	0.00318357234662
ko04380	Osteoclast differentiation	1/453	134/7206	0.0032763860595
ko04713	Circadian entrainment	1/453	136/7206	0.00341789975596
ko04510	Focal adhesion	5/453	240/7206	0.00402291729446
ko04722	Neurotrophin signaling pathway	2/453	160/7206	0.00432447210717
ko04660	T cell receptor signaling pathway	1/453	124/7206	0.00464069670951
ko04922	Glucagon signaling pathway	1/453	128/7206	0.00480561016805
ko04261	Adrenergic signaling in cardiomyocytes	4/453	205/7206	0.00521539378991
ko04142	Lysosome	2/453	151/7206	0.00599149182824
ko05160	Hepatitis C	2/453	153/7206	0.00611297167547
ko00230	Purine metabolism	22/453	194/7206	0.00634956440252
ko04911	Insulin secretion	1/453	117/7206	0.00676627884218
ko00670	One carbon pool by folate	5/453	20/7206	0.00676764630444
ko04668	TNF signaling pathway	1/453	120/7206	0.00683712949154
ko04912	GnRH signaling pathway	1/453	122/7206	0.00704076845119
ko04750	Inflammatory mediator regulation of TRP channels	1/453	122/7206	0.00704076845119
ko04666	Fc gamma R-mediated phagocytosis	1/453	122/7206	0.00704076845119
ko04066	HIF-1 signaling pathway	1/453	123/7206	0.00719067377408
ko05217	Basal cell carcinoma	10/453	68/7206	0.00945698789571
ko04972	Pancreatic secretion	1/453	111/7206	0.00982789832078
ko05414	Dilated cardiomyopathy	1/453	112/7206	0.00983509955269
ko05418	Fluid shear stress and atherosclerosis	3/453	173/7206	0.00993286257705
ko05016	Huntington's disease	5/453	215/7206	0.00996482858531
ko04931	Insulin resistance	2/453	137/7206	0.0120291848751
ko04728	Dopaminergic synapse	4/453	185/7206	0.0135765933343
ko05152	Tuberculosis	4/453	187/7206	0.0136625057926
ko04925	Aldosterone synthesis and secretion	1/453	105/7206	0.0142607951727
ko04659	Th17 cell differentiation	1/453	106/7206	0.014296530495
ko01521	EGFR tyrosine kinase inhibitor resistance	1/453	106/7206	0.014296530495
ko04330	Notch signaling pathway	9/453	62/7206	0.0146441844317
ko04012	ErbB signaling pathway	1/453	109/7206	0.014771974957
ko04630	Jak-STAT signaling pathway	2/453	132/7206	0.0171487504747
ko04217	Necroptosis	4/453	178/7206	0.0185455842067
ko05100	Bacterial invasion of epithelial cells	1/453	99/7206	0.0206709092221
ko04720	Long-term potentiation	1/453	99/7206	0.0206709092221
ko00564	Glycerophospholipid metabolism	1/453	99/7206	0.0206709092221
ko05410	Hypertrophic cardiomyopathy (HCM)	1/453	100/7206	0.0207582491826
ko05145	Toxoplasmosis	2/453	126/7206	0.0242877956266
ko05211	Renal cell carcinoma	1/453	96/7206	0.0308052631851
ko04658	Th1 and Th2 cell differentiation	1/453	96/7206	0.0308052631851
ko04140	Autophagy - animal	4/453	164/7206	0.0342155700299
ko04068	FoxO signaling pathway	4/453	167/7206	0.0344455413434
ko04530	Tight junction	7/453	228/7206	0.0375323782484
ko04360	Axon guidance	7/453	233/7206	0.0380553664876
ko04924	Renin secretion	1/453	86/7206	0.0431085445726
ko04917	Prolactin signaling pathway	1/453	87/7206	0.0432674427529
ko04146	Peroxisome	1/453	89/7206	0.0440663605375
ko04152	AMPK signaling pathway	4/453	161/7206	0.0466887490887
ko04070	Phosphatidylinositol signaling system	2/453	112/7206	0.0474918805617