ko pathway ratio_in_study ratio_in_pop p_value ko00380 Tryptophan metabolism 11/175 50/7206 2.07811516711e-08 ko00350 Tyrosine metabolism 9/175 33/7206 5.587933959e-08 ko00643 Styrene degradation 4/175 4/7206 3.36315191592e-07 ko00140 Steroid hormone biosynthesis 9/175 41/7206 4.29385078571e-07 ko00360 Phenylalanine metabolism 6/175 17/7206 1.86631742876e-06 ko00120 Primary bile acid biosynthesis 6/175 20/7206 5.50060828056e-06 ko04974 Protein digestion and absorption 11/175 96/7206 1.86170410274e-05 ko05204 Chemical carcinogenesis 7/175 48/7206 0.000140370054066 ko03320 PPAR signaling pathway 8/175 69/7206 0.000243691851729 ko00362 Benzoate degradation 3/175 6/7206 0.000266834927035 ko00983 Drug metabolism - other enzymes 6/175 42/7206 0.000477794548952 ko04080 Neuroactive ligand-receptor interaction 1/175 423/7206 0.000482460216689 ko04610 Complement and coagulation cascades 8/175 79/7206 0.00061881416517 ko04976 Bile secretion 8/175 80/7206 0.000673571075157 ko00071 Fatty acid degradation 6/175 45/7206 0.0006985272027 ko00260 Glycine, serine and threonine metabolism 6/175 48/7206 0.000991006010995 ko05133 Pertussis 8/175 87/7206 0.00117585094704 ko00100 Steroid biosynthesis 4/175 21/7206 0.00145558040915 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/175 11/7206 0.00201222282346 ko05134 Legionellosis 7/175 74/7206 0.00202094662645 ko00830 Retinol metabolism 5/175 42/7206 0.00327789547157 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/175 4/7206 0.00340726291515 ko00561 Glycerolipid metabolism 6/175 63/7206 0.00406691407833 ko04972 Pancreatic secretion 8/175 111/7206 0.00543557300255 ko00232 Caffeine metabolism 2/175 5/7206 0.00558820822743 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/175 5/7206 0.00558820822743 ko00281 Geraniol degradation 2/175 5/7206 0.00558820822743 ko00640 Propanoate metabolism 4/175 34/7206 0.00882757114507 ko00410 beta-Alanine metabolism 4/175 35/7206 0.00978154738045 ko04975 Fat digestion and absorption 4/175 35/7206 0.00978154738045 ko05150 Staphylococcus aureus infection 4/175 36/7206 0.0108000776487 ko05160 Hepatitis C 9/175 153/7206 0.0119778759723 ko04630 Jak-STAT signaling pathway 8/175 132/7206 0.0147866720984 ko00053 Ascorbate and aldarate metabolism 3/175 22/7206 0.015440900487 ko00980 Metabolism of xenobiotics by cytochrome P450 4/175 40/7206 0.0155492453828 ko01230 Biosynthesis of amino acids 6/175 85/7206 0.0169324654485 ko04144 Endocytosis 2/175 342/7206 0.0177360514245 ko00220 Arginine biosynthesis 3/175 24/7206 0.0195894796408 ko04146 Peroxisome 6/175 89/7206 0.0207948069038 ko04920 Adipocytokine signaling pathway 6/175 89/7206 0.0207948069038 ko00950 Isoquinoline alkaloid biosynthesis 2/175 10/7206 0.0232157772444 ko00401 Novobiocin biosynthesis 1/175 1/7206 0.0242853177908 ko00040 Pentose and glucuronate interconversions 3/175 26/7206 0.0242932015503 ko04064 NF-kappa B signaling pathway 6/175 96/7206 0.0289160461461 ko05132 Salmonella infection 6/175 98/7206 0.0315719432759 ko00280 Valine, leucine and isoleucine degradation 4/175 54/7206 0.0415061274974 ko00300 Lysine biosynthesis 1/175 2/7206 0.0479841476847 ko00254 Aflatoxin biosynthesis 1/175 2/7206 0.0479841476847 ko05131 Shigellosis 5/175 82/7206 0.048658863763 ko04931 Insulin resistance 7/175 137/7206 0.0488588156299