ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 36/231 145/7206 7.92312244055e-23 ko05322 Systemic lupus erythematosus 28/231 151/7206 2.12408386587e-14 ko04111 Cell cycle - yeast 18/231 90/7206 3.21584843733e-10 ko04110 Cell cycle 22/231 145/7206 8.94875429819e-10 ko05034 Alcoholism 28/231 238/7206 1.73389461844e-09 ko03008 Ribosome biogenesis in eukaryotes 13/231 79/7206 1.08741591489e-06 ko03410 Base excision repair 8/231 38/7206 2.10204334861e-05 ko05202 Transcriptional misregulation in cancer 18/231 188/7206 2.98801830218e-05 ko03015 mRNA surveillance pathway 12/231 93/7206 3.7018933689e-05 ko04113 Meiosis - yeast 10/231 70/7206 6.91328980985e-05 ko03013 RNA transport 15/231 166/7206 0.000264970183846 ko04151 PI3K-Akt signaling pathway 2/231 390/7206 0.000513043056901 ko03030 DNA replication 6/231 38/7206 0.00118727944518 ko04014 Ras signaling pathway 1/231 279/7206 0.00159326774058 ko04217 Necroptosis 14/231 178/7206 0.00166745961096 ko03440 Homologous recombination 6/231 41/7206 0.00178495105771 ko03430 Mismatch repair 4/231 22/7206 0.00477509373646 ko04114 Oocyte meiosis 11/231 139/7206 0.00490465709408 ko03460 Fanconi anemia pathway 6/231 51/7206 0.00548026351963 ko04144 Endocytosis 3/231 342/7206 0.00700358707539 ko00240 Pyrimidine metabolism 9/231 110/7206 0.00855557446805 ko05203 Viral carcinogenesis 17/231 277/7206 0.00858472288113 ko04024 cAMP signaling pathway 2/231 279/7206 0.00889162264191 ko04261 Adrenergic signaling in cardiomyocytes 1/231 205/7206 0.0151316196716 ko04921 Oxytocin signaling pathway 1/231 209/7206 0.0152192277482 ko03420 Nucleotide excision repair 5/231 46/7206 0.0152450691601 ko04022 cGMP-PKG signaling pathway 1/231 216/7206 0.0160014525647 ko05166 HTLV-I infection 17/231 292/7206 0.0160876253766 ko04072 Phospholipase D signaling pathway 1/231 197/7206 0.0220263071708 ko04218 Cellular senescence 11/231 177/7206 0.0295503954337 ko04141 Protein processing in endoplasmic reticulum 1/231 184/7206 0.0316821316754 ko04728 Dopaminergic synapse 1/231 185/7206 0.0318084224731 ko05152 Tuberculosis 1/231 187/7206 0.0321536628878 ko04010 MAPK signaling pathway 4/231 321/7206 0.0351000644354 ko04530 Tight junction 2/231 228/7206 0.0351421648724 ko04015 Rap1 signaling pathway 3/231 278/7206 0.0359718966139 ko04120 Ubiquitin mediated proteolysis 9/231 138/7206 0.0435452336895 ko05164 Influenza A 1/231 167/7206 0.0452542248867 ko04810 Regulation of actin cytoskeleton 3/231 264/7206 0.049216817367