ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 33/376 191/7206 7.2056984287e-10 ko04380 Osteoclast differentiation 27/376 134/7206 8.19116384573e-10 ko04621 NOD-like receptor signaling pathway 28/376 157/7206 7.17558833569e-09 ko04064 NF-kappa B signaling pathway 20/376 96/7206 7.53735712195e-08 ko05145 Toxoplasmosis 23/376 126/7206 1.05806619856e-07 ko05164 Influenza A 27/376 167/7206 1.14211308721e-07 ko04620 Toll-like receptor signaling pathway 19/376 100/7206 7.30747297842e-07 ko05140 Leishmaniasis 16/376 75/7206 1.10640279592e-06 ko05340 Primary immunodeficiency 10/376 30/7206 1.55950215404e-06 ko04610 Complement and coagulation cascades 16/376 79/7206 2.30276496616e-06 ko04659 Th17 cell differentiation 18/376 106/7206 7.66264404872e-06 ko05133 Pertussis 16/376 87/7206 8.61335261969e-06 ko05161 Hepatitis B 24/376 173/7206 9.49826646201e-06 ko05152 Tuberculosis 25/376 187/7206 1.19818405588e-05 ko04668 TNF signaling pathway 19/376 120/7206 1.22781863987e-05 ko05162 Measles 19/376 120/7206 1.22781863987e-05 ko04660 T cell receptor signaling pathway 19/376 124/7206 1.98717428758e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 20/376 135/7206 2.00533230176e-05 ko05321 Inflammatory bowel disease (IBD) 12/376 56/7206 2.3641487298e-05 ko04658 Th1 and Th2 cell differentiation 16/376 96/7206 3.12735201147e-05 ko05323 Rheumatoid arthritis 15/376 89/7206 4.82662671534e-05 ko05150 Staphylococcus aureus infection 9/376 36/7206 6.97419418498e-05 ko04672 Intestinal immune network for IgA production 9/376 37/7206 8.79765761865e-05 ko05142 Chagas disease (American trypanosomiasis) 18/376 130/7206 0.000128038318777 ko04650 Natural killer cell mediated cytotoxicity 15/376 97/7206 0.000133551575435 ko04662 B cell receptor signaling pathway 14/376 88/7206 0.000163408583078 ko04512 ECM-receptor interaction 13/376 79/7206 0.000196872806107 ko05131 Shigellosis 13/376 82/7206 0.000288671965982 ko04670 Leukocyte transendothelial migration 19/376 151/7206 0.000300228539002 ko04622 RIG-I-like receptor signaling pathway 11/376 62/7206 0.000308983058362 ko05144 Malaria 9/376 45/7206 0.000432560585943 ko05034 Alcoholism 2/376 238/7206 0.000504661096583 ko04657 IL-17 signaling pathway 13/376 87/7206 0.000522604740932 ko05168 Herpes simplex infection 21/376 182/7206 0.000537835978867 ko04611 Platelet activation 19/376 163/7206 0.000935070666472 ko04623 Cytosolic DNA-sensing pathway 8/376 41/7206 0.00106772980342 ko05160 Hepatitis C 18/376 153/7206 0.00121872383215 ko04723 Retrograde endocannabinoid signaling 1/376 175/7206 0.00156375465675 ko04062 Chemokine signaling pathway 21/376 201/7206 0.00198897174716 ko04664 Fc epsilon RI signaling pathway 11/376 77/7206 0.00201335049897 ko03013 RNA transport 1/376 166/7206 0.00226373401726 ko05167 Kaposi's sarcoma-associated herpesvirus infection 20/376 191/7206 0.00256412634876 ko04217 Necroptosis 19/376 178/7206 0.00295987184055 ko00120 Primary bile acid biosynthesis 5/376 20/7206 0.00304464864908 ko04630 Jak-STAT signaling pathway 15/376 132/7206 0.00431168110813 ko05132 Salmonella infection 12/376 98/7206 0.00476213081207 ko00140 Steroid hormone biosynthesis 7/376 41/7206 0.00480344583455 ko04666 Fc gamma R-mediated phagocytosis 14/376 122/7206 0.00570631810157 ko04728 Dopaminergic synapse 2/376 185/7206 0.0063430171456 ko04916 Melanogenesis 1/376 142/7206 0.00697177282256 ko03040 Spliceosome 1/376 145/7206 0.00708476706405 ko04068 FoxO signaling pathway 17/376 167/7206 0.00732204969404 ko04514 Cell adhesion molecules (CAMs) 14/376 130/7206 0.00849496873437 ko04072 Phospholipase D signaling pathway 19/376 197/7206 0.00855661162884 ko04210 Apoptosis 18/376 180/7206 0.00940543753401 ko05134 Legionellosis 9/376 74/7206 0.0142733859172 ko05166 HTLV-I infection 25/376 292/7206 0.0145930060174 ko01200 Carbon metabolism 1/376 128/7206 0.014713819636 ko03010 Ribosome 1/376 129/7206 0.0148057826108 ko05320 Autoimmune thyroid disease 5/376 29/7206 0.0158666608756 ko04974 Protein digestion and absorption 11/376 96/7206 0.0166256623912 ko04640 Hematopoietic cell lineage 8/376 64/7206 0.0174616108956 ko05146 Amoebiasis 11/376 99/7206 0.0184662018683 ko05016 Huntington's disease 4/376 215/7206 0.0189077267337 ko00051 Fructose and mannose metabolism 6/376 42/7206 0.020695738866 ko04145 Phagosome 15/376 162/7206 0.0295261705541 ko04972 Pancreatic secretion 1/376 111/7206 0.030570036965 ko05330 Allograft rejection 4/376 24/7206 0.0338506565921 ko04510 Focal adhesion 20/376 240/7206 0.0370623115474 ko05212 Pancreatic cancer 9/376 83/7206 0.039644015892 ko05220 Chronic myeloid leukemia 9/376 85/7206 0.0425573065678 ko04727 GABAergic synapse 1/376 110/7206 0.0467094288167 ko05215 Prostate cancer 11/376 111/7206 0.0475356961954 ko05222 Small cell lung cancer 9/376 89/7206 0.0499254324565