ko pathway ratio_in_study ratio_in_pop p_value ko04080 Neuroactive ligand-receptor interaction 18/65 423/7206 1.83743398241e-08 ko05032 Morphine addiction 8/65 110/7206 5.59464246321e-06 ko04726 Serotonergic synapse 8/65 137/7206 2.81849248012e-05 ko04725 Cholinergic synapse 8/65 160/7206 8.54279215449e-05 ko04727 GABAergic synapse 6/65 110/7206 0.000438584284726 ko04070 Phosphatidylinositol signaling system 6/65 112/7206 0.000483061526772 ko04723 Retrograde endocannabinoid signaling 7/65 175/7206 0.000938578670438 ko05033 Nicotine addiction 4/65 56/7206 0.00155803202083 ko04925 Aldosterone synthesis and secretion 5/65 105/7206 0.00246542847222 ko04020 Calcium signaling pathway 8/65 265/7206 0.00246611531822 ko04921 Oxytocin signaling pathway 7/65 209/7206 0.00260977369326 ko04911 Insulin secretion 5/65 117/7206 0.00393835602814 ko04728 Dopaminergic synapse 6/65 185/7206 0.00621318385337 ko04710 Circadian rhythm 3/65 43/7206 0.00668506668653 ko04971 Gastric acid secretion 4/65 98/7206 0.0115623775416 ko04024 cAMP signaling pathway 7/65 279/7206 0.0123493620383 ko04071 Sphingolipid signaling pathway 5/65 162/7206 0.0150770156253 ko04742 Taste transduction 3/65 61/7206 0.0173841018621 ko04540 Gap junction 4/65 128/7206 0.0279704746685 ko05134 Legionellosis 3/65 74/7206 0.0288377010392 ko05143 African trypanosomiasis 2/65 32/7206 0.0334021557126 ko04713 Circadian entrainment 4/65 136/7206 0.0339028194589 ko04916 Melanogenesis 4/65 142/7206 0.0388006249665 ko04918 Thyroid hormone synthesis 3/65 86/7206 0.0422120136193 ko04724 Glutamatergic synapse 4/65 152/7206 0.0478243930636