ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	31/443	56/7206	1.3663611751e-23
ko04724	Glutamatergic synapse	42/443	152/7206	2.36501785496e-17
ko04728	Dopaminergic synapse	46/443	185/7206	6.1578428971e-17
ko04080	Neuroactive ligand-receptor interaction	72/443	423/7206	3.97684772857e-16
ko04721	Synaptic vesicle cycle	29/443	80/7206	8.60670063861e-16
ko04723	Retrograde endocannabinoid signaling	40/443	175/7206	1.53442919936e-13
ko04727	GABAergic synapse	31/443	110/7206	2.37859079515e-13
ko05032	Morphine addiction	29/443	110/7206	9.07646359141e-12
ko04713	Circadian entrainment	31/443	136/7206	1.01421637472e-10
ko04024	cAMP signaling pathway	45/443	279/7206	1.37784123184e-09
ko04261	Adrenergic signaling in cardiomyocytes	37/443	205/7206	1.88139950565e-09
ko05031	Amphetamine addiction	22/443	91/7206	1.79135912192e-08
ko04911	Insulin secretion	25/443	117/7206	2.78440370887e-08
ko04921	Oxytocin signaling pathway	35/443	209/7206	3.90109712905e-08
ko04720	Long-term potentiation	22/443	99/7206	9.18812053806e-08
ko04725	Cholinergic synapse	29/443	160/7206	1.02982762873e-07
ko04020	Calcium signaling pathway	39/443	265/7206	2.69955260671e-07
ko04010	MAPK signaling pathway	44/443	321/7206	3.27083818545e-07
ko05030	Cocaine addiction	17/443	73/7206	1.3518569967e-06
ko04514	Cell adhesion molecules (CAMs)	23/443	130/7206	3.40196288221e-06
ko04726	Serotonergic synapse	23/443	137/7206	8.4948572662e-06
ko04970	Salivary secretion	18/443	95/7206	1.50242917071e-05
ko04260	Cardiac muscle contraction	18/443	98/7206	2.34220867072e-05
ko05203	Viral carcinogenesis	3/443	277/7206	3.44290294026e-05
ko04730	Long-term depression	15/443	78/7206	6.44362739543e-05
ko04022	cGMP-PKG signaling pathway	29/443	216/7206	6.50088486915e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/443	79/7206	7.51449386492e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	14/443	74/7206	0.000135362090146
ko04742	Taste transduction	12/443	61/7206	0.000276455645937
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/443	14/7206	0.00108061013686
ko05010	Alzheimer's disease	24/443	202/7206	0.00159443962263
ko04070	Phosphatidylinositol signaling system	16/443	112/7206	0.00204136014567
ko04924	Renin secretion	13/443	86/7206	0.00211622666995
ko04060	Cytokine-cytokine receptor interaction	3/443	191/7206	0.00346093325765
ko04972	Pancreatic secretion	15/443	111/7206	0.00392637291994
ko04966	Collecting duct acid secretion	6/443	26/7206	0.00418293585699
ko05110	Vibrio cholerae infection	10/443	63/7206	0.0047006125463
ko04925	Aldosterone synthesis and secretion	14/443	105/7206	0.00597061374578
ko04072	Phospholipase D signaling pathway	22/443	197/7206	0.00607720451139
ko05162	Measles	1/443	120/7206	0.00678950199896
ko05168	Herpes simplex infection	3/443	182/7206	0.00698104942663
ko05169	Epstein-Barr virus infection	4/443	206/7206	0.00732968451425
ko04964	Proximal tubule bicarbonate reclamation	6/443	29/7206	0.00738165439721
ko04745	Phototransduction - fly	7/443	38/7206	0.00757288220483
ko05322	Systemic lupus erythematosus	2/443	151/7206	0.00887710149486
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/443	59/7206	0.00931728123115
ko04740	Olfactory transduction	11/443	80/7206	0.00934162072234
ko05410	Hypertrophic cardiomyopathy (HCM)	13/443	100/7206	0.0095960128686
ko05164	Influenza A	3/443	167/7206	0.0133438040476
ko00240	Pyrimidine metabolism	1/443	110/7206	0.0145319452901
ko04371	Apelin signaling pathway	19/443	177/7206	0.0162486497459
ko04630	Jak-STAT signaling pathway	2/443	132/7206	0.0170628763478
ko04120	Ubiquitin mediated proteolysis	2/443	138/7206	0.017848587248
ko04971	Gastric acid secretion	12/443	98/7206	0.0183985564353
ko04626	Plant-pathogen interaction	4/443	18/7206	0.0216447123282
ko00562	Inositol phosphate metabolism	11/443	89/7206	0.0232924241574
ko05414	Dilated cardiomyopathy	13/443	112/7206	0.0260062812261
ko05205	Proteoglycans in cancer	8/443	271/7206	0.0271306883727
ko05120	Epithelial cell signaling in Helicobacter pylori infection	11/443	92/7206	0.0276610368033
ko04722	Neurotrophin signaling pathway	17/443	160/7206	0.0281283633858
ko04071	Sphingolipid signaling pathway	17/443	162/7206	0.0294664910707
ko04978	Mineral absorption	6/443	40/7206	0.033821969591
ko04110	Cell cycle	3/443	145/7206	0.0348980642844
ko04973	Carbohydrate digestion and absorption	6/443	42/7206	0.0417358656509
ko04940	Type I diabetes mellitus	5/443	32/7206	0.0437555021079
ko04930	Type II diabetes mellitus	7/443	54/7206	0.0459649753275
ko05166	HTLV-I infection	10/443	292/7206	0.0462912161518
ko04611	Platelet activation	4/443	163/7206	0.0464126093733